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JAZZ logo JAZZ
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Jazz Pharmaceuticals PLC (JAZZ)

Upturn stock ratingUpturn stock rating
$106.12
Last Close (24-hour delay)
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PASS
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Upturn Stock infoUpturn Stock info Stock price based on last close
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Upturn Advisory Summary

06/30/2025: JAZZ (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

18 Analysts rated it

These Stocks/ETFs, based on Upturn Advisory, frequently surpass the market, reflecting reliable and trustworthy advice.

Year Target Price $188.01

Year Target Price $188.01

Analyst’s Price TargetsFor last 52 week
$188.01Target price
Low$95.49
Current$106.12
high$148.06

Analysis of Past Performance

Type Stock
Historic Profit -14.69%
Avg. Invested days 36
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 6.47B USD
Price to earnings Ratio 14.52
1Y Target Price 188.01
Price to earnings Ratio 14.52
1Y Target Price 188.01
Volume (30-day avg) 18
Beta 0.33
52 Weeks Range 95.49 - 148.06
Updated Date 06/29/2025
52 Weeks Range 95.49 - 148.06
Updated Date 06/29/2025
Dividends yield (FY) -
Basic EPS (TTM) 7.36

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin 11.86%
Operating Margin (TTM) -2.9%

Management Effectiveness

Return on Assets (TTM) 3.99%
Return on Equity (TTM) 12.25%

Valuation

Trailing PE 14.52
Forward PE 12.17
Enterprise Value 9318807585
Price to Sales(TTM) 1.59
Enterprise Value 9318807585
Price to Sales(TTM) 1.59
Enterprise Value to Revenue 2.29
Enterprise Value to EBITDA 7.46
Shares Outstanding 60511000
Shares Floating 59666753
Shares Outstanding 60511000
Shares Floating 59666753
Percent Insiders 3.07
Percent Institutions 101.94

Analyst Ratings

Rating 4
Target Price 188.01
Buy 6
Strong Buy 10
Buy 6
Strong Buy 10
Hold 2
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Jazz Pharmaceuticals PLC

stock logo

Company Overview

overview logo History and Background

Jazz Pharmaceuticals was founded in 2003 in Ireland, focusing on developing pharmaceutical products to treat unmet medical needs. Initially focused on sleep disorders, it expanded through acquisitions and internal development.

business area logo Core Business Areas

  • Sleep: Focuses on treatments for narcolepsy and idiopathic hypersomnia, including products like Xyrem and Xywav.
  • Oncology: Develops and markets treatments for hematologic malignancies and solid tumors, including products like Defitelio and Zepzelca.
  • Movement Disorders: Focuses on treatments for movement disorders like Parkinson's disease.

leadership logo Leadership and Structure

Bruce Cozadd is the Chairman and CEO. The company has a structured management team across various functional areas like research and development, commercial operations, and finance.

Top Products and Market Share

overview logo Key Offerings

  • Market Share (%): 60
  • Xywav/Xyrem: Treatment for narcolepsy. Xywav revenue was approximately $1.26B in 2023, and Xyrem revenue was approximately $209.4M. This is for US sales. Competitors include Avadel Pharmaceuticals with Lumryz.
  • Epidiolex/Epidyolex: Treatment for seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC) in patients one year of age and older. US revenue in 2023 was approximately $518M. Competitors include GW Pharmaceuticals (acquired by Jazz) and other anti-epileptic drugs.
  • Market Share (%): 20
  • Market Share (%): 10
  • Zepzelca: Treatment for small cell lung cancer. Generated revenues of approximately $248M in 2023. Competitors include standard chemotherapy regimens and other targeted therapies.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry is characterized by intense competition, high R&D costs, and stringent regulatory requirements. Growth is driven by innovation, aging populations, and increasing healthcare spending.

Positioning

Jazz Pharmaceuticals is a specialty pharmaceutical company with a strong focus on sleep disorders and oncology. Its competitive advantages include established brands, a robust pipeline, and a strong market presence in its niche areas.

Total Addressable Market (TAM)

The TAM for sleep disorders and oncology is estimated to be billions of dollars. Jazz is well-positioned to capture a significant portion through its established products and ongoing research.

Upturn SWOT Analysis

Strengths

  • Strong market position in sleep disorders
  • Diversified product portfolio
  • Established distribution network
  • Experienced management team
  • Strong R&D capabilities

Weaknesses

  • Reliance on key products (Xyrem/Xywav)
  • Exposure to generic competition
  • High debt level
  • Dependence on successful clinical trials

Opportunities

  • Expansion into new therapeutic areas
  • Acquisitions of complementary businesses
  • Development of new formulations and indications
  • Increased global presence
  • Leveraging data analytics for improved patient outcomes

Threats

  • Patent expirations
  • Regulatory changes
  • Competition from larger pharmaceutical companies
  • Pricing pressures
  • Clinical trial failures

Competitors and Market Share

competitor logo Key Competitors

  • Avadel Pharmaceuticals (AVDL)
  • Supernus Pharmaceuticals (SUPN)
  • Lundbeck (LUN.CO)

Competitive Landscape

Jazz faces competition from larger pharmaceutical companies and smaller biotech firms. Its competitive advantage lies in its specialized focus and established market presence.

Major Acquisitions

GW Pharmaceuticals

  • Year: 2021
  • Acquisition Price (USD millions): 7200
  • Strategic Rationale: Expanded Jazz's neuroscience portfolio with the addition of Epidiolex, a cannabidiol (CBD) oral solution approved for the treatment of seizures associated with several rare epilepsies.

Growth Trajectory and Initiatives

Historical Growth: Jazz has experienced significant growth through acquisitions and product development. Revenue has increased steadily over the past decade.

Future Projections: Analysts project continued revenue growth driven by Xywav and its oncology portfolio. Future growth depends on the success of clinical trials and new product launches.

Recent Initiatives: Recent initiatives include acquisitions, pipeline development, and strategic partnerships to expand its therapeutic focus.

Summary

Jazz Pharmaceuticals is a specialized pharmaceutical company with strong positions in sleep disorders and oncology. Its strength lies in its established brands and diversified product portfolio. However, it faces challenges from generic competition and the need to develop new products. The GW Pharmaceuticals acquisition has bolstered its portfolio and pipeline.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company SEC Filings (10-K, 10-Q)
  • Analyst Reports
  • Company Investor Relations
  • Third-party financial data providers
  • Company Press Releases

Disclaimers:

The information provided is for informational purposes only and should not be considered investment advice. Market share data are estimates and may vary depending on the source.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Jazz Pharmaceuticals PLC

Exchange NASDAQ
Headquaters -
IPO Launch date 2007-06-01
Co-Founder, Chairman & CEO Mr. Bruce C. Cozadd
Sector Healthcare
Industry Biotechnology
Full time employees 2800
Full time employees 2800

Jazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products in the United States, Europe, and internationally. The company offers Xywav to treat cataplexy or excessive daytime sleepiness (EDS) with narcolepsy and idiopathic hypersomnia (IH); Xyrem for the treatment of cataplexy or EDS with narcolepsy; Epidiolex for seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC); Rylaze for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma; Enrylaze to treat acute lymphoblastic leukemia and lymphoblastic lymphoma; Zepzelca for the treatment of metastatic small cell lung cancer with disease progression on or after platinum-based chemotherapy; Ziihera to treat HER2-positive biliary tract cancers; Defitelio to treat severe veno-occlusive disease; and Vyxeos for the treatment of newly-diagnosed therapy-related acute myeloid leukemia. It also develops Zanidatamab in Phase 3 trial to treat HER2-expressing gastroesophageal adenocarcinoma (GEA), and patients with HER2-expressing metastatic GEA; Epidiolex in Phase 3 trial to treat LGS, DS, and TSC; Suvecaltamide in Phase 2 trial to treat Parkinson's disease tremor; JZP815, a pan-RAF kinase inhibitor in Phase 1 trial that targets components of the mitogen-activated protein kinase; JZP898, a conditionally activated interferon alpha molecule in Phase 1 trial; JZP441 in Phase 1 trial to treat narcolepsy, IH, and other sleep disorders; JZP324, an extended-release low sodium oxybate formulation in Phase 1 trial for patients with sleep disorders; and JZP150 to treat post-traumatic stress disorder. The company has licensing and collaboration agreements with Redx Pharma plc, Autifony Therapeutics Limited, Zymeworks Inc., Sumitomo Pharma Co., Ltd., and Werewolf Therapeutics, Inc. Jazz Pharmaceuticals plc was founded in 2003 and is headquartered in Dublin, Ireland.