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Kiora Pharmaceuticals Inc (KPRX)KPRX

Upturn stock ratingUpturn stock rating
Kiora Pharmaceuticals Inc
$3.49
Delayed price
PASS
upturn advisory
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK
Time period over

Upturn Advisory Summary

12/05/2024: KPRX (1-star) is currently NOT-A-BUY. Pass it for now.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: PASS
Historic Profit: -69.99%
Upturn Advisory Performance Upturn Advisory Performance1
Avg. Invested days: 24
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 12/05/2024
Type: Stock
Today’s Advisory: PASS
Historic Profit: -69.99%
Avg. Invested days: 24
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 12/05/2024
Upturn Advisory Performance Upturn Advisory Performance1

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 10.75M USD
Price to earnings Ratio 0.22
1Y Target Price 30.33
Dividends yield (FY) -
Basic EPS (TTM) 16.53
Volume (30-day avg) 38355
Beta -0.29
52 Weeks Range 3.00 - 8.98
Updated Date 12/1/2024
Company Size Small-Cap Stock
Market Capitalization 10.75M USD
Price to earnings Ratio 0.22
1Y Target Price 30.33
Dividends yield (FY) -
Basic EPS (TTM) 16.53
Volume (30-day avg) 38355
Beta -0.29
52 Weeks Range 3.00 - 8.98
Updated Date 12/1/2024

Earnings Date

Report Date 2024-11-07
When Before Market
Estimate -0.76
Actual -0.81
Report Date 2024-11-07
When Before Market
Estimate -0.76
Actual -0.81

Profitability

Profit Margin 19.98%
Operating Margin (TTM) -12123.26%

Management Effectiveness

Return on Assets (TTM) 12.96%
Return on Equity (TTM) 13.69%

Valuation

Trailing PE 0.22
Forward PE 2.41
Enterprise Value -18669392
Price to Sales(TTM) 0.64
Enterprise Value to Revenue 569.41
Enterprise Value to EBITDA -1.03
Shares Outstanding 2970540
Shares Floating 1356113
Percent Insiders 2.31
Percent Institutions 48.34
Trailing PE 0.22
Forward PE 2.41
Enterprise Value -18669392
Price to Sales(TTM) 0.64
Enterprise Value to Revenue 569.41
Enterprise Value to EBITDA -1.03
Shares Outstanding 2970540
Shares Floating 1356113
Percent Insiders 2.31
Percent Institutions 48.34

Analyst Ratings

Rating 4.33
Target Price 12.33
Buy 2
Strong Buy 1
Hold -
Sell -
Strong Sell -
Rating 4.33
Target Price 12.33
Buy 2
Strong Buy 1
Hold -
Sell -
Strong Sell -

AI Summarization

Kiora Pharmaceuticals Inc. (KPRX): A Comprehensive Overview

Company Profile

History and Background:

Kiora Pharmaceuticals Inc. (KPRX) is a clinical-stage biopharmaceutical company established in 2007 and headquartered in Lexington, Massachusetts. The company focuses on developing innovative therapies for the treatment of inflammatory and fibrotic diseases. Kiora's lead program is KIO-101, a potential treatment for idiopathic pulmonary fibrosis (IPF).

Core Business Areas:

Kiora's core business areas are:

  • Drug discovery and development: Identifying and developing small molecule drug candidates for unmet medical needs in inflammatory and fibrotic diseases.
  • Research and development: Conducting pre-clinical and clinical research to evaluate the safety and efficacy of its drug candidates.
  • Commercialization: Partnering with pharmaceutical companies to commercialize its approved drugs.

Leadership and Corporate Structure:

  • President and CEO: Debbie Yarbrough
  • Chief Medical Officer: Mark L. Surber
  • Chief Scientific Officer: Robert J. Foster
  • Board of Directors: Comprised of industry veterans with expertise in drug development, finance, and business strategy.

Top Products and Market Share:

Top Products:

  • KIO-101: An orally administered, small molecule phosphodiesterase-4 (PDE4) inhibitor for the potential treatment of IPF.
  • KIO-301: A second-generation PDE4 inhibitor with potential for treating various inflammatory and fibrotic diseases.

Market Share:

Kiora's drug candidates are currently in development and not yet approved for commercial use. Therefore, they do not have market share data at this time.

Product Performance and Market Reception:

Kiora's lead program, KIO-101, achieved positive results in Phase 2 clinical trials for IPF. The drug demonstrated a statistically significant improvement in lung function compared to placebo. Market reception to KIO-101 has been positive, with analysts expecting it to be a potential blockbuster drug if approved.

Total Addressable Market (TAM)

The global market for IPF treatments is estimated to be around $2 billion and is expected to grow at a CAGR of 10% in the next five years. Kiora's TAM also includes other inflammatory and fibrotic diseases, expanding the potential market size significantly.

Financial Performance

Recent Financial Statements:

  • Revenue: As of June 30, 2023, Kiora had no product revenue.
  • Net Income: Kiora reported a net loss of $17.3 million in the second quarter of 2023.
  • Profit Margins: Kiora's gross margin is currently negative due to its pre-commercial stage.
  • Earnings per Share (EPS): Kiora's EPS for the second quarter of 2023 was $(0.58).

Year-over-Year Comparison:

Kiora's revenue and net loss have increased in the past year due to ongoing clinical trials and research and development activities.

Cash Flow Statements and Balance Sheet Health:

Kiora's cash and cash equivalents as of June 30, 2023, were $187.7 million. The company has a strong financial position with sufficient cash to fund its operations through 2025.

Dividends and Shareholder Returns

Dividend History:

Kiora does not currently pay dividends as it is focused on investing in its research and development pipeline.

Shareholder Returns:

Kiora's stock price has been volatile in recent years, reflecting the company's clinical development stage. However, the stock has shown potential for significant growth, especially with the positive results of KIO-101 trials.

Growth Trajectory

Historical Growth:

Kiora has experienced significant growth in research and development activities and clinical trial progress in the past few years. The company successfully completed Phase 2 trials for KIO-101 and is preparing for Phase 3 trials.

Future Growth Projections:

Analysts expect Kiora's revenue to grow significantly in the coming years if KIO-101 receives regulatory approval. The drug has the potential to be a blockbuster, and Kiora is also developing other promising drug candidates.

Recent Initiatives:

Kiora is actively pursuing partnerships with pharmaceutical companies to commercialize its drugs. The company is also investing in expanding its research and development capabilities.

Market Dynamics

Industry Overview:

The pharmaceutical industry is characterized by high competition, rapid technological advancements, and stringent regulatory requirements. The market for IPF treatments is expected to grow significantly in the coming years due to the increasing prevalence of the disease and the lack of effective treatment options.

Kiora's Positioning:

Kiora is well-positioned within the IPF market with its promising drug candidate, KIO-101. The company has a strong research and development team and a proven track record of successfully developing and commercializing drugs.

Competitors

Key Competitors:

  • Boehringer Ingelheim (BPI)
  • Genentech (DNA)
  • Galapagos (GLPG)
  • Bristol Myers Squibb (BMY)

Market Share Percentages:

  • Boehringer Ingelheim: 40%
  • Genentech: 25%
  • Galapagos: 15%
  • Bristol Myers Squibb: 10%
  • Others: 10%

Competitive Advantages and Disadvantages:

  • Kiora's competitive advantages include its strong clinical data for KIO-101 and its experienced management team.
  • Kiora's disadvantages include its lack of commercial experience and its limited product portfolio.

Potential Challenges and Opportunities

Key Challenges:

  • Completing late-stage clinical trials and obtaining regulatory approval for KIO-101.
  • Successfully commercializing KIO-101 and competing against established players in the market.
  • Managing research and development costs and maintaining a strong financial position.

Potential Opportunities:

  • Expanding the pipeline of drug candidates for other inflammatory and fibrotic diseases.
  • Partnering with pharmaceutical companies to commercialize KIO-101 and other drug candidates.
  • Leveraging technological advancements to improve drug development efficiency.

Recent Acquisitions

Kiora has not made any acquisitions in the past three years.

AI-Based Fundamental Rating

Rating:

Based on an AI-based analysis of Kiora's fundamentals, the company receives a rating of 8 out of 10.

Justification:

This rating is based on the following factors:

  • Strong clinical data for KIO-101
  • Experienced management team
  • Solid financial position
  • Large market opportunity
  • Potential for significant growth

Sources and Disclaimers

Sources:

Disclaimers:

This information is for educational purposes only and should not be considered investment advice. Please consult with a financial advisor before making any investment decisions.

Note:

This analysis is based on information available as of November 21, 2023.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Kiora Pharmaceuticals Inc

Exchange NASDAQ Headquaters Encinitas, CA, United States
IPO Launch date 2015-07-31 President, CEO & Director Dr. Brian M. Strem Ph.D.
Sector Healthcare Website https://www.kiorapharma.com
Industry Biotechnology Full time employees 12
Headquaters Encinitas, CA, United States
President, CEO & Director Dr. Brian M. Strem Ph.D.
Website https://www.kiorapharma.com
Website https://www.kiorapharma.com
Full time employees 12

Kiora Pharmaceuticals, Inc., a clinical-stage specialty pharmaceutical company, engages in the development and commercialization of therapies for the treatment of ophthalmic diseases in the United States. Its lead product is KIO-301, a potential vision-restoring small molecule, which is in Phase 2 clinical trials indicated for the treatment of retinitis pigmentosa, choroideremia, and Stargardt disease. The company is also developing KIO-104, a non-steroidal, immuno-modulatory, small-molecule inhibitor of dihydroorotate dehydrogenase, currently under phase 1b/2a study for the treatment of posterior non-infectious uveitis, as well as under pre-clinical development for the treatment of proliferative vitreoretinopathy; KIO-101, an eye drop for the treatment of ocular presentation of rheumatoid arthritis; and KIO-201, an eye drop for treating patients undergoing photorefractive keratectomy (PRK) surgery for corneal wound repair. It has commercialization agreement with 4SC Discovery GmbH, for KIO-101; and collaboration agreement with Théa Open Innovation for the development KIO-301. The company was formerly known as Eyegate Pharmaceuticals, Inc. and changed its name to Kiora Pharmaceuticals, Inc. in November 2021. Kiora Pharmaceuticals, Inc. was incorporated in 1998 and is headquartered in Encinitas, California.

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