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Frequency Therapeutics Inc (KRRO)



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Upturn Advisory Summary
08/14/2025: KRRO (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $100.83
1 Year Target Price $100.83
6 | Strong Buy |
4 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -56.28% | Avg. Invested days 20 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 145.46M USD | Price to earnings Ratio - | 1Y Target Price 100.83 |
Price to earnings Ratio - | 1Y Target Price 100.83 | ||
Volume (30-day avg) 10 | Beta - | 52 Weeks Range 10.29 - 98.00 | Updated Date 08/5/2025 |
52 Weeks Range 10.29 - 98.00 | Updated Date 08/5/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -10.6 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -981.18% |
Management Effectiveness
Return on Assets (TTM) -29.82% | Return on Equity (TTM) -60.22% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 75690721 | Price to Sales(TTM) 30.17 |
Enterprise Value 75690721 | Price to Sales(TTM) 30.17 | ||
Enterprise Value to Revenue 15.7 | Enterprise Value to EBITDA -5.6 | Shares Outstanding 9390490 | Shares Floating 4888127 |
Shares Outstanding 9390490 | Shares Floating 4888127 | ||
Percent Insiders 6.17 | Percent Institutions 104.25 |
Upturn AI SWOT
Frequency Therapeutics Inc
Company Overview
History and Background
Frequency Therapeutics Inc. was founded in 2014 and is focused on developing therapies to activate progenitor cells within the body to restore healthy tissue. They are focused on hearing loss treatment.
Core Business Areas
- Hearing Loss Therapeutics: Development of small molecule therapeutics to regenerate hair cells in the inner ear to treat sensorineural hearing loss.
Leadership and Structure
David L. Lucchino is the President and CEO. The company operates with a typical biotech organizational structure with research, development, and business operations departments.
Top Products and Market Share
Key Offerings
- FX-322: FX-322 is Frequency Therapeutics' lead drug candidate for sensorineural hearing loss. It is currently in clinical development. There is no market share data, but it is an experimental drug. Competitors include other companies developing hearing loss treatments, such as Decibel Therapeutics (DBTX).
Market Dynamics
Industry Overview
The hearing loss therapeutics industry is characterized by a large unmet need and growing aging population. Advancements in regenerative medicine are driving innovation.
Positioning
Frequency Therapeutics is positioned as a leader in regenerative medicine for hearing loss, focusing on activating inner ear progenitor cells. Their competitive advantage lies in their proprietary platform.
Total Addressable Market (TAM)
The hearing loss market is estimated to be in the billions of dollars. Frequency Therapeutics is positioned to capture a portion of this market with their regenerative approach, assuming successful clinical trials and regulatory approvals.
Upturn SWOT Analysis
Strengths
- Proprietary platform technology for activating progenitor cells
- Experienced management team
- Strong intellectual property portfolio
Weaknesses
- Dependence on success of lead candidate FX-322
- High cash burn rate
- Clinical trial risk and regulatory hurdles
Opportunities
- Positive clinical trial results for FX-322
- Partnerships with pharmaceutical companies
- Expansion of pipeline into other regenerative medicine applications
Threats
- Failure of clinical trials
- Competition from established pharmaceutical companies
- Regulatory challenges
Competitors and Market Share
Key Competitors
- DBTX
Competitive Landscape
Frequency Therapeutics faces competition from companies with alternative approaches to treating hearing loss. Their regenerative medicine approach is a differentiator but also carries risk.
Growth Trajectory and Initiatives
Historical Growth: Historical growth is characterized by research and development advancements, not revenue growth.
Future Projections: Future growth depends on clinical trial success and regulatory approvals for FX-322. Analyst estimates depend heavily on these milestones.
Recent Initiatives: Recent initiatives focus on advancing FX-322 through clinical trials and exploring partnerships.
Summary
Frequency Therapeutics is a high-risk, high-reward biotech company focused on regenerative medicine for hearing loss. The company is focused on FX-322, and its future depends on its success. Clinical trials and regulatory hurdles pose significant risks to their business model, but successful commercialization would be a game changer. They must secure further funding or partnerships to survive.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company SEC Filings
- Company Website
- Analyst Reports
- ClinicalTrials.gov
Disclaimers:
This analysis is for informational purposes only and does not constitute investment advice. Investment decisions should be made based on individual research and consultation with a qualified financial advisor. The data presented is based on publicly available information and may be subject to change. Market share numbers are estimates and may not be precise.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Frequency Therapeutics Inc
Exchange NASDAQ | Headquaters Cambridge, MA, United States | ||
IPO Launch date 2023-11-06 | CEO, President & Director Dr. Ram Aiyar MBA, Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 112 | Website https://www.korrobio.com |
Full time employees 112 | Website https://www.korrobio.com |
Korro Bio, Inc., a biopharmaceutical company, engages in the discovering, developing, and commercializing of genetic medicines based on editing RNA for the treatment of rare and highly prevalent diseases in the United States. Its lead product candidate is KRRO-110 which is in Phase 1/2 clinical trial for the treatment of Alpha-1 Antitrypsin Deficiency (AATD). It uses its RNA editing platform, Oligonucleotide Promoted Editing of RNA to generate differentiated RNA editing product candidates. The company is also developing programs for Parkinson's disease, Amyotrophic lateral sclerosis, severe drug-associated anesthetics, and other pain indications. Korro Bio, Inc. has a collaboration agreement with Novo Nordisk A/S to treat cardiometabolic diseases. Korro Bio, Inc. was founded in 2018 and is based in Cambridge, Massachusetts.

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