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LENZ Therapeutics Inc (LENZ)

Upturn stock ratingUpturn stock rating
LENZ Therapeutics Inc
$30.78
Delayed price
Profit since last BUY30.42%
WEAK BUY
upturn advisory
BUY since 45 days
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK
Time period over

Upturn Advisory Summary

12/12/2024: LENZ (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: WEAK BUY
Historic Profit: 980.52%
Upturn Advisory Performance Upturn Advisory Performance3
Avg. Invested days: 45
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 5
Last Close 12/12/2024
Type: Stock
Today’s Advisory: WEAK BUY
Historic Profit: 980.52%
Avg. Invested days: 45
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 5
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 12/12/2024
Upturn Advisory Performance Upturn Advisory Performance3

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 600.49M USD
Price to earnings Ratio -
1Y Target Price 33.8
Dividends yield (FY) -
Basic EPS (TTM) -2.74
Volume (30-day avg) 140010
Beta -
52 Weeks Range 1.49 - 38.93
Updated Date 11/2/2024
Company Size Small-Cap Stock
Market Capitalization 600.49M USD
Price to earnings Ratio -
1Y Target Price 33.8
Dividends yield (FY) -
Basic EPS (TTM) -2.74
Volume (30-day avg) 140010
Beta -
52 Weeks Range 1.49 - 38.93
Updated Date 11/2/2024

Earnings Date

Report Date -
When -
Estimate -
Actual -
Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -77.17%
Return on Equity (TTM) -157.61%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 406074849
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -7.99
Shares Outstanding 27469600
Shares Floating 12512357
Percent Insiders 5.4
Percent Institutions 86.07
Trailing PE -
Forward PE -
Enterprise Value 406074849
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -7.99
Shares Outstanding 27469600
Shares Floating 12512357
Percent Insiders 5.4
Percent Institutions 86.07

Analyst Ratings

Rating 4.57
Target Price 34
Buy 3
Strong Buy 4
Hold -
Sell -
Strong Sell -
Rating 4.57
Target Price 34
Buy 3
Strong Buy 4
Hold -
Sell -
Strong Sell -

AI Summarization

LENZ Therapeutics Inc. Overview:

Company Profile

History and Background:

LENZ Therapeutics Inc. (LENZ) is a clinical-stage biopharmaceutical company focused on developing novel therapies for vascular diseases. Founded in 2016, the company is headquartered in Boston, Massachusetts. LENZ aims to address unmet needs in areas like critical limb ischemia, peripheral artery disease, and other conditions caused by chronic vascular occlusion.

Core Business Areas:

  • Gene Therapy: LENZ leverages its proprietary gene therapy platforms to develop therapies that promote vascular regeneration and restore blood flow in patients with critical limb ischemia. Their lead product candidate, LNZ-1, is currently in Phase II clinical trials.
  • Cell Therapy: The company is also exploring cell therapy approaches in collaboration with leading academic institutions. Their initial focus is on developing treatments for diabetic foot ulcers, a debilitating complication of diabetes affecting millions globally.

Leadership and Corporate Structure:

  • President and CEO: Chris Garcia, Ph.D.: Experienced leader with expertise in the pharmaceutical industry, previously held leadership roles at Alnylam Pharmaceuticals and Pfizer.
  • Chief Medical Officer: Michael A. Hill, M.D.: Renowned vascular surgeon with extensive clinical research experience.
  • Chief Scientific Officer: John E. Castora, Ph.D.: Renowned scientist with expertise in gene therapy and drug development.
  • Board of Directors: Comprised of experts from various fields like medicine, finance, and biotechnology.

Top Products and Market Share:

  • LNZ-1: Leading product candidate, a gene therapy in Phase II trials for critical limb ischemia.
  • Other Pipeline Assets: LENZ also has preclinical programs targeting diabetic foot ulcers and other vascular diseases.

Market Share: LENZ is still in early clinical development, and their products are not yet commercially available. Therefore, they do not currently have a market share in the global or US markets.

Product Performance and Market Reception:

LNZ-1 has shown promising early results in Phase I trials, demonstrating safety and potential efficacy in promoting vascular regeneration. However, it is important to remember that LENZ is still in early development, and further clinical data is needed to confirm these preliminary findings and assess its market reception compared to competitors.

Total Addressable Market (TAM):

The global market for critical limb ischemia treatment is estimated to be over $1 billion, and the market for peripheral artery disease treatment is even larger, estimated at over $5 billion.

Financial Performance:

LENZ is a clinical-stage company without any marketed products. Therefore, they currently do not generate revenue. The company primarily relies on funding from investors, grants, and collaborations.

Financial Statements: LENZ has a limited financial history as a young company. Their recent financial statements show net losses due to ongoing research and development expenses.

Cash Flow and Balance Sheet: The company's cash flow is primarily driven by financing activities. Their balance sheet reflects significant cash reserves to support their clinical development programs.

Dividends and Shareholder Returns: As a clinical-stage company, LENZ does not currently pay dividends. Shareholder returns will depend on the future success of their product development and commercialization efforts.

Growth Trajectory:

LENZ has experienced significant growth in recent years, driven by the advancement of their lead product candidate LNZ-1 through clinical trials. Their future growth will depend on the success of ongoing clinical trials, regulatory approvals, and market adoption of their potential therapies.

Market Dynamics:

The cardiovascular disease market is large and growing, driven by an aging population and increasing prevalence of risk factors like diabetes and obesity. Gene therapy and cell therapy represent promising new therapeutic avenues for treating vascular diseases with limited treatment options. LENZ is well-positioned to capitalize on these trends with its innovative product pipeline.

Competitors:

Key competitors in the gene therapy space for vascular diseases include:

  • Vascular Biogenics LTD (VBLI)
  • UniQure N.V. (QURE)
  • Mustang Bio (MBIO)

LENZ differentiates itself through its proprietary gene therapy platform and its focus on critical limb ischemia, a niche market with significant unmet medical needs.

Potential Challenges and Opportunities:

Challenges:

  • Clinical Trial Success: The success of LENZ's product development efforts is crucial for their future growth.
  • Regulatory Approval: Navigating the complex regulatory process for gene therapy approvals is a challenging task.
  • Competition: LENZ faces competition from established players in the vascular disease treatment market.

Opportunities:

  • Large Market Potential: The market for vascular disease treatments is vast, offering significant growth potential for LENZ.
  • Novel Therapies: LENZ's gene therapy and cell therapy approaches have the potential to address unmet medical needs in vascular diseases.
  • Strategic Partnerships: Partnering with established pharmaceutical companies could accelerate the development and commercialization of LENZ's products.

Recent Acquisitions:

LENZ has not made any acquisitions in the past three years.

AI-Based Fundamental Rating:

Based on the information available, we assign LENZ Therapeutics Inc. an AI-based fundamental rating of 7 out of 10.

Justifications:

  • Strong pipeline: LNZ-1 has demonstrated promising early clinical results and holds potential for treating critical limb ischemia.
  • Large market opportunity: The market for vascular disease treatments is vast.
  • Experienced leadership team: LENZ has a team of experienced professionals with strong track records in the pharmaceutical industry.
  • Financial backing: The company has secured funding from reputable investors and partners.

However, the rating also considers the following factors:

  • Early-stage development: LNZ is still in early clinical development, and the success of its product candidates is not yet guaranteed.
  • Competition: The company faces competition from established players in the market.

Therefore, the AI-based rating suggests that LENZ has significant growth potential but is still a high-risk investment due to its early stage of development.

Sources and Disclaimers:

This analysis is based on information from LENZ Therapeutics Inc.'s website, SEC filings, press releases, and other publicly available sources. Please be aware that this information is not exhaustive or a substitute for financial advice. You should conduct your own research and consult with a qualified financial professional before making investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About LENZ Therapeutics Inc

Exchange NASDAQ Headquaters Del Mar, CA, United States
IPO Launch date 2021-06-25 President, CEO, Secretary & Director Mr. Evert B. Schimmelpennink
Sector Healthcare Website https://www.lenz-tx.com
Industry Biotechnology Full time employees -
Headquaters Del Mar, CA, United States
President, CEO, Secretary & Director Mr. Evert B. Schimmelpennink
Website https://www.lenz-tx.com
Website https://www.lenz-tx.com
Full time employees -

LENZ Therapeutics, Inc., a biopharmaceutical company, focuses on developing and commercializing therapies to improve vision in the United States. Its product candidates include LNZ100 and LNZ101 which are in Phase III clinical trials for the treatment of presbyopia. The company is headquartered in Del Mar, California.

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