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Lantheus Holdings Inc (LNTH)

Upturn stock ratingUpturn stock rating
$50.84
Last Close (24-hour delay)
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PASS
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Upturn Advisory Summary

09/17/2025: LNTH (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

13 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $86.64

1 Year Target Price $86.64

Analysts Price Target For last 52 week
$86.64 Target price
52w Low $47.25
Current$50.84
52w High $118.21

Analysis of Past Performance

Type Stock
Historic Profit -30.12%
Avg. Invested days 36
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/17/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 3.53B USD
Price to earnings Ratio 13.82
1Y Target Price 86.64
Price to earnings Ratio 13.82
1Y Target Price 86.64
Volume (30-day avg) 13
Beta 0.15
52 Weeks Range 47.25 - 118.21
Updated Date 09/17/2025
52 Weeks Range 47.25 - 118.21
Updated Date 09/17/2025
Dividends yield (FY) -
Basic EPS (TTM) 3.76

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin 17.82%
Operating Margin (TTM) 23.27%

Management Effectiveness

Return on Assets (TTM) 13.34%
Return on Equity (TTM) 24.71%

Valuation

Trailing PE 13.82
Forward PE 8.56
Enterprise Value 3454257865
Price to Sales(TTM) 2.32
Enterprise Value 3454257865
Price to Sales(TTM) 2.32
Enterprise Value to Revenue 2.27
Enterprise Value to EBITDA 7.55
Shares Outstanding 67994200
Shares Floating 63181523
Shares Outstanding 67994200
Shares Floating 63181523
Percent Insiders 2.24
Percent Institutions 117.21

ai summary icon Upturn AI SWOT

Lantheus Holdings Inc

stock logo

Company Overview

overview logo History and Background

Lantheus Holdings, Inc. was founded in 1956. It initially focused on contrast agents and diagnostic imaging. Over time, it expanded its portfolio and shifted towards precision diagnostics and therapies.

business area logo Core Business Areas

  • Precision Diagnostics: Develops, manufactures, and distributes diagnostic imaging agents that help physicians visualize and assess diseases in the body. Includes products for cardiac, cancer and other diseases.
  • Therapeutic Applications: Focuses on developing and commercializing therapeutics, particularly in the field of prostate cancer.

leadership logo Leadership and Structure

The CEO of Lantheus Holdings is Mary Anne Heino. The company has a typical corporate structure with departments such as R&D, Sales & Marketing, Operations, and Finance.

Top Products and Market Share

overview logo Key Offerings

  • Pylarify: A PSMA-targeted PET imaging agent used for prostate cancer staging. Pylarify is a leading product for Lantheus, with strong growth and high profit margins. It has a significant market share. Competitors include Blue Earth Diagnostics and Progenics Pharmaceuticals (now part of Lantheus).
  • DEFINITY: An ultrasound contrast agent used to enhance cardiac imaging. It is a well-established product with a solid market share, competing with GE Healthcare and Bracco Diagnostics.

Market Dynamics

industry overview logo Industry Overview

The diagnostic imaging market is growing, driven by an aging population, increasing prevalence of chronic diseases, and technological advancements. The market is competitive, with many players offering various imaging modalities and contrast agents.

Positioning

Lantheus is positioned as a leader in precision diagnostics and therapeutics, particularly in prostate cancer imaging. Its competitive advantage lies in its innovative products, strong distribution network, and focus on specialized areas.

Total Addressable Market (TAM)

The overall nuclear medicine and precision diagnostics market is estimated to be worth billions of dollars annually. Lantheus is focused on capturing a significant share of the market, particularly in the prostate cancer imaging segment.

Upturn SWOT Analysis

Strengths

  • Strong product portfolio with leading positions in key markets
  • Innovative products and technologies
  • Experienced management team
  • Established distribution network

Weaknesses

  • Reliance on a few key products
  • Exposure to regulatory risks
  • Competition from larger players
  • Potential for product obsolescence due to technological advancements

Opportunities

  • Expanding into new therapeutic areas
  • Acquiring complementary technologies and products
  • Partnering with other companies to expand market reach
  • Developing new diagnostic imaging agents

Threats

  • Increased competition
  • Pricing pressures
  • Changes in reimbursement policies
  • Product liability claims

Competitors and Market Share

competitor logo Key Competitors

  • GE (GE)
  • BRACCO DIAGNOSTICS
  • IBA Molecular

Competitive Landscape

Lantheus competes with larger, more diversified companies. Lantheus's competitive advantage lies in its specialization, innovative products, and strong customer relationships. It needs to continue to innovate and expand its portfolio to maintain its market position.

Major Acquisitions

Progenics Pharmaceuticals

  • Year: 2020
  • Acquisition Price (USD millions): 250
  • Strategic Rationale: To expand its pipeline of radiopharmaceutical oncology products, particularly targeting prostate cancer.

Growth Trajectory and Initiatives

Historical Growth: Lantheus has experienced solid growth in recent years, driven by strong sales of its key products, particularly Pylarify.

Future Projections: Future growth is projected to be driven by continued adoption of Pylarify, expansion into new therapeutic areas, and strategic acquisitions.

Recent Initiatives: Recent initiatives include the acquisition of Progenics Pharmaceuticals, the launch of new products, and expansion of its manufacturing capacity.

Summary

Lantheus is a strong company in the precision diagnostics market. The company's prostate cancer imaging portfolio, particularly Pylarify, is driving growth. Lantheus needs to be careful to maintain its market share against larger competitors, while also expanding its pipeline to decrease reliance on a single key product.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Lantheus Holdings Investor Relations
  • Industry Reports
  • Analyst Estimates

Disclaimers:

The information provided is for informational purposes only and should not be considered as financial advice. Investment decisions should be made based on individual research and consultation with a qualified financial advisor. Market share is an estimate based on available information and may not be precise.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Lantheus Holdings Inc

Exchange NASDAQ
Headquaters Bedford, MA, United States
IPO Launch date 2015-06-25
CEO & Director Mr. Brian A. Markison
Sector Healthcare
Industry Drug Manufacturers - Specialty & Generic
Full time employees 808
Full time employees 808

Lantheus Holdings, Inc. develops, manufactures, and commercializes diagnostic and therapeutic products that assist clinicians in diagnosis and treatment of heart, cancer, and other diseases worldwide. The company offers DEFINITY, an injectable ultrasound enhancing agent used in echocardiography exams; TechneLite, a technetium generator for nuclear medicine procedures; Xenon-133, a radiopharmaceutical gas to assess pulmonary function; Neurolite, an injectable imaging agent to identify the area within the brain where blood flow has been blocked or reduced due to stroke; Cardiolite, an injectable Tc-99m-labeled imaging agent to assess blood flow to the muscle of the heart; and PYLARIFY, an F 18-labelled PSMA-targeted PET imaging agent used for imaging of PSMA positive-lesions in men with prostate cancer. It also provides Automated Bone Scan Index that calculates the disease burden of prostate cancer by detecting and classifying bone scan tracer uptakes as metastatic or benign lesions using an artificial neural network; RELISTOR for opioid-induced constipation; and aPROMISE, an artificial intelligence medical device software; PYLARIFY AI, an medical device software to perform quantitative assessment of PSMA PET/CT images in prostate cancer; and flurpiridaz used to assess blood flow to the heart. In addition, it develops 1095, a PSMA-targeted iodine-131-labeled small molecule; PNT2002, a radiopharmaceutical therapy to treat mCRPC; PNT2003, an SSTR therapy to patients with SSTR-positive neuroendocrine tumors; MK-6240, a F 18-labeled PET imaging agent for Tau tangles in Alzheimer's disease; LNTH-2401, a novel radiodiagnostic targeting the gastrin-releasing peptide receptor; LNTH-2402; LNTH-2403; LNTH-2404; and LNTH-1363S, an fibroblast activation protein, alpha, copper-64 labeled PET imaging agent. It has collaboration agreements with GE Healthcare; POINT; Regeneron; and Ratio Therapeutics LLC. The company was founded in 1956 and is based in Bedford, Massachusetts.