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Upturn AI Summary - About
Lisata Therapeutics Inc.(LSTA)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for LSTA
11/05/2026: LSTA (1-star) is currently NOT-A-BUY. Pass it for now.
Lisata Therapeutics is a clinical-stage biotechnology company focused on advancing its proprietary CEND platform to enhance the efficacy of oncology treatments for solid tumors. The company's main strength lies in its innovative drug delivery technology, which seeks to improve outcomes in high-unmet-need areas. Its primary growth story centers on the successful validation and clinical progression of its lead asset, LSTA-1. Key risks include the high execution risk of clinical-stage development, potential dilution from necessary capital raises, and intense competition from major pharmaceutical firms. The stock is best suited for speculative growth investors who can tolerate high volatility and should monitor upcoming clinical trial readouts for signs of progress.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | This is a speculative play on biotechnology R&D success rather than established earnings growth. |
| Momentum investor | Strong fit while signal remains positive | Momentum traders may focus on clinical data readouts or potential partnerships. |
| Value investor | Weak fit | The company lacks current profitability and established cash flows for traditional value analysis. |
| Dividend investor | Weak fit | The company does not pay dividends and prioritizes cash for clinical development. |
| Low-risk investor | Weak fit | The high inherent risk of clinical-stage drug development makes this unsuitable for low-risk portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical-stage biotech stocks are susceptible to massive price swings based on data announcements. |
| Valuation risk | High | Valuations are highly speculative as there are no current commercial products to support traditional models. |
| Competition risk (Oncology drug development) | High | Large pharmaceutical competitors dominate the oncology space with deep pockets and established clinical infrastructure. |
| Business quality | Medium | The company is in an early, high-risk stage of the drug development lifecycle. |
| Dividend income | Low / none | No income generation is expected for the foreseeable future. |
| Execution risk | High | Success depends entirely on the ability to execute complex clinical trials and achieve regulatory milestones. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit -32.76% | Avg. Invested days 31 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/05/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 10.71M USD | Price to earnings Ratio - | 1Y Target Price 4 |
Price to earnings Ratio - | 1Y Target Price 4 | ||
Volume (30-day avg) 90.2K shares | Beta 1.02 | 52 Weeks Range 0.96 - 5.07 | Updated Date 11/05/2026 |
52 Weeks Range 0.96 - 5.07 | Updated Date 11/05/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.64 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Oncology Research | Clinical trial development and licensing of the CEND platform. | The company earns money primarily through potential future licensing or drug sales, not current operations. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE - | Forward PE 2.71 | Enterprise Value -10.47M | Price to Sales(TTM) 107.12 |
Enterprise Value -10.47M | Price to Sales(TTM) 107.12 | ||
Enterprise Value to Revenue 59.6 | Enterprise Value to EBITDA 0.82 | Shares Outstanding 10.80M | Shares Floating 6.91M |
Shares Outstanding 10.80M | Shares Floating 6.91M | ||
Percent Insiders 20.57 | Percent Institutions 11.06 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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