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Lisata Therapeutics Inc. (LSTA)

Upturn stock ratingUpturn stock rating
$2.28
Last Close (24-hour delay)
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
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Upturn Advisory Summary

09/17/2025: LSTA (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

3 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $20.67

1 Year Target Price $20.67

Analysts Price Target For last 52 week
$20.67 Target price
52w Low $1.87
Current$2.28
52w High $4.2

Analysis of Past Performance

Type Stock
Historic Profit -43.15%
Avg. Invested days 31
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/17/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 20.14M USD
Price to earnings Ratio -
1Y Target Price 20.67
Price to earnings Ratio -
1Y Target Price 20.67
Volume (30-day avg) 3
Beta 1.01
52 Weeks Range 1.87 - 4.20
Updated Date 09/17/2025
52 Weeks Range 1.87 - 4.20
Updated Date 09/17/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.23

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -6954.29%

Management Effectiveness

Return on Assets (TTM) -38.76%
Return on Equity (TTM) -64.4%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -1784320
Price to Sales(TTM) 18.82
Enterprise Value -1784320
Price to Sales(TTM) 18.82
Enterprise Value to Revenue 0.32
Enterprise Value to EBITDA 0.82
Shares Outstanding 8755950
Shares Floating 7259644
Shares Outstanding 8755950
Shares Floating 7259644
Percent Insiders 19.82
Percent Institutions 8.94

ai summary icon Upturn AI SWOT

Lisata Therapeutics Inc.

stock logo

Company Overview

overview logo History and Background

Lisata Therapeutics, Inc. (formerly D u09b8u09c1u09afu09cbu0997, Inc.) focuses on the development of therapies that target the tumor microenvironment. Founded with the goal of enhancing cancer treatments, it has evolved through various stages of clinical development and strategic partnerships.

business area logo Core Business Areas

  • Drug Development: Developing and commercializing innovative therapies that are designed to modulate the tumor microenvironment and promote efficient and selective delivery of cancer therapeutics to solid tumors.
  • Clinical Trials: Conducting clinical trials to evaluate the safety and efficacy of its lead product candidates in various cancer types.

leadership logo Leadership and Structure

The leadership team consists of experienced executives in the pharmaceutical and biotechnology industries. The organizational structure is designed to support research, clinical development, and potential commercialization efforts.

Top Products and Market Share

overview logo Key Offerings

  • LSTA (formerly TLX101): Lisata's lead product candidate, designed to target the tumor microenvironment. It's currently in clinical trials for various cancers. Market share is currently 0% as it is still in development phase. Competitors include companies developing similar tumor-targeted therapies.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry, specifically oncology, is characterized by high growth potential, intense competition, and significant regulatory hurdles. Tumor microenvironment-targeted therapies represent a growing area of research and development.

Positioning

Lisata is positioned as a company focused on developing innovative therapies that address the challenges of drug delivery in solid tumors. Its competitive advantage lies in its targeted approach to modulating the tumor microenvironment.

Total Addressable Market (TAM)

The global oncology market is vast, expected to reach hundreds of billions of dollars. Lisata's TAM depends on the success of LSTA and its applicability to various cancer types. TAM estimates will be in the hundreds of billions by 2030. Their current position is minimal (less than .0001%)

Upturn SWOT Analysis

Strengths

  • Novel targeted therapy approach
  • Experienced management team
  • Clinical-stage product candidate
  • Proprietary technology platform

Weaknesses

  • Limited financial resources
  • Reliance on a single lead product candidate
  • High regulatory risk
  • No current revenue generation

Opportunities

  • Potential for strategic partnerships
  • Expansion into new cancer indications
  • Positive clinical trial results
  • Advancements in drug delivery technologies

Threats

  • Competition from established pharmaceutical companies
  • Clinical trial failures
  • Regulatory delays
  • Difficulty in securing funding

Competitors and Market Share

competitor logo Key Competitors

  • BMRN
  • MRTX
  • LLY

Competitive Landscape

Lisata's advantage lies in its targeted approach. Disadvantages include limited resources and a reliance on a single product candidate compared to larger pharmaceutical companies.

Growth Trajectory and Initiatives

Historical Growth: Historical Growth: Limited historical growth due to being in a developmental phase.

Future Projections: Future Projections: Dependent on the success of clinical trials and regulatory approvals. Analyst estimates vary widely.

Recent Initiatives: Recent Initiatives: Focus on advancing clinical trials and securing partnerships.

Summary

Lisata Therapeutics is a development-stage biopharmaceutical company focused on tumor microenvironment modulation. It has a promising lead product candidate but faces significant risks related to clinical trials and regulatory approvals. The company's success hinges on the positive outcome of its clinical programs and its ability to secure funding and partnerships. Its lack of revenue and dependence on a single asset make it a speculative investment. Any failure in clinical trials will have a severe negative consequence for the company.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Analyst reports

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. Investment decisions should be based on individual research and consultation with a financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Lisata Therapeutics Inc.

Exchange NASDAQ
Headquaters Basking Ridge, NJ, United States
IPO Launch date 1999-03-01
President, CEO & Director Dr. David J. Mazzo B.A. (Hons), B.Sc. (Hons.), M.Sc., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 26
Full time employees 26

Lisata Therapeutics, Inc., a clinical-stage pharmaceutical company, engages in the discovery, development, and commercialization of therapies for the treatment of solid tumors and other diseases. Its investigational product is certepetide, which is in Phase 2 clinical studies for the treatment of solid tumors, such as metastatic pancreatic ductal adenocarcinoma, cholangiocarcinoma, appendiceal cancer, and colon cancer and glioblastoma multiforme in combination with a range of anti-cancer regimens. The company was incorporated in 1980 and is headquartered in Basking Ridge, New Jersey.