MGX
MGX 1-star rating from Upturn Advisory

Metagenomi, Inc. Common Stock (MGX)

Metagenomi, Inc. Common Stock (MGX) 1-star rating from Upturn Advisory
$1.6
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PASS
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Upturn Advisory Summary

12/01/2025: MGX (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

2 star rating from financial analysts

7 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $9.33

1 Year Target Price $9.33

Analysts Price Target For last 52 week
$9.33 Target price
52w Low $1.23
Current$1.6
52w High $4.92

Analysis of Past Performance

Type Stock
Historic Profit -11.53%
Avg. Invested days 29
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 12/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 65.71M USD
Price to earnings Ratio -
1Y Target Price 9.33
Price to earnings Ratio -
1Y Target Price 9.33
Volume (30-day avg) 7
Beta -
52 Weeks Range 1.23 - 4.92
Updated Date 12/1/2025
52 Weeks Range 1.23 - 4.92
Updated Date 12/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.39

Earnings Date

Report Date 2025-11-12
When -
Estimate -0.8
Actual -0.55

Profitability

Profit Margin -287.06%
Operating Margin (TTM) -263.76%

Management Effectiveness

Return on Assets (TTM) -19.02%
Return on Equity (TTM) -40.87%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -76744186
Price to Sales(TTM) 2.13
Enterprise Value -76744186
Price to Sales(TTM) 2.13
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding 37546751
Shares Floating 27049055
Shares Outstanding 37546751
Shares Floating 27049055
Percent Insiders 28.09
Percent Institutions 17.9

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI SWOT

Metagenomi, Inc. Common Stock

Metagenomi, Inc. Common Stock(MGX) company logo displayed in Upturn AI summary

Company Overview

Company history and background logo History and Background

Metagenomi, Inc. is a biopharmaceutical company focused on discovering and developing novel, potentially curative gene editing therapies. The company was founded in 2018. It leverages metagenomics to identify and engineer novel CRISPR-associated (Cas) systems.

Company business area logo Core Business Areas

  • Gene Editing Therapies: Focuses on developing gene editing therapies for various diseases using novel CRISPR systems identified through metagenomics.
  • Metagenomics Platform: Utilizes a proprietary metagenomics platform to discover and engineer new gene editing tools and technologies.

leadership logo Leadership and Structure

Brian C. Thomas is the CEO of Metagenomi. The company has a board of directors and a management team overseeing research, development, and business operations.

Top Products and Market Share

Product Key Offerings logo Key Offerings

  • mgEDIT: A versatile gene editing platform derived from environmental microbes, offering improved specificity and efficiency. It is still in preclinical development. Competitors include CRISPR Therapeutics (CRSP), Intellia Therapeutics (NTLA), and Editas Medicine (EDIT).
  • Novel Cas Enzymes: Discovering and engineering new Cas enzymes with unique properties for gene editing. Currently being researched and developed for various therapeutic applications.Competitors include CRISPR Therapeutics (CRSP), Intellia Therapeutics (NTLA), and Editas Medicine (EDIT).

Market Dynamics

industry overview logo Industry Overview

The gene editing industry is rapidly growing, driven by advancements in CRISPR technology and the potential to treat a wide range of genetic diseases. The space is competitive and quickly changing.

Positioning

Metagenomi is positioned as an innovator in gene editing, leveraging its metagenomics platform to discover novel CRISPR systems with potentially improved safety and efficacy profiles compared to existing technologies.

Total Addressable Market (TAM)

The total addressable market for gene editing therapies is estimated to be tens of billions of dollars. Metagenomi is positioned to capture a portion of this market with its novel gene editing platforms. It is estimated to reach $11.7 billion by 2027.

Upturn SWOT Analysis

Strengths

  • Proprietary metagenomics platform
  • Novel CRISPR systems with unique properties
  • Experienced management team
  • Strong intellectual property position

Weaknesses

  • Early-stage company with no approved products
  • Dependence on research and development success
  • High cash burn rate
  • Competition from established gene editing companies

Opportunities

  • Partnerships with pharmaceutical companies
  • Expansion into new therapeutic areas
  • Advancement of lead programs into clinical trials
  • Potential for breakthrough therapies

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from other gene editing technologies
  • Intellectual property disputes

Competitors and Market Share

Key competitor logo Key Competitors

  • CRSP
  • NTLA
  • EDIT

Competitive Landscape

Metagenomi's competitive advantage lies in its novel CRISPR systems discovered through its metagenomics platform. However, it faces significant competition from larger, more established gene editing companies with greater resources.

Growth Trajectory and Initiatives

Historical Growth: Metagenomi went public in Feb 2024. It's difficult to determine the historical growth without available and older public financial information.

Future Projections: Future growth is dependent on advancing its gene editing programs through clinical trials and securing partnerships. Analyst estimates for revenue growth vary widely.

Recent Initiatives: Focus on advancing its lead gene editing programs into clinical trials, expanding its metagenomics platform, and forging strategic partnerships.

Summary

Metagenomi is a promising early-stage gene editing company with a unique metagenomics platform. Its novel CRISPR systems offer potential advantages over existing technologies. However, the company faces significant risks related to clinical trial success, regulatory approvals, and competition. Its early stage makes it a very risky but possibly high reward investment.

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Sources and Disclaimers

Data Sources:

  • Company Website
  • SEC Filings
  • Analyst Reports

Disclaimers:

The information provided is for informational purposes only and does not constitute investment advice. Please consult with a qualified financial advisor before making any investment decisions.

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Information icon for Upturn AI Summarization data freshness disclaimer Summarized information shown could be a few years old and not current.

Information icon warning about Upturn AI Fundamental Rating based on potentially old data Fundamental Rating based on AI could be based on old data.

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About Metagenomi, Inc. Common Stock

Exchange NASDAQ
Headquaters EmeryVille, CA, United States
IPO Launch date 2024-02-09
CEO, President, COO & Director Dr. Jian Irish M.B.A., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 124
Full time employees 124

Metagenomi, Inc., a genetic medicines company, develops therapeutics for patients using metagenomics-derived genome editing toolbox in the United States. Its genome editing toolbox includes nuclease-based genome editing, base editors, RNA-mediated integration, including prime editing, and DNA-mediated integration, such CRISPR-associated transposases. The company has a collaboration and license agreement with Ionis Pharmaceuticals, Inc. to research, develop and commercialize investigational medicines using genome editing technologies; and a development, option, and license agreement with Affini-T Therapeutics, Inc. to develop and commercialize gene edited TCR-based therapeutic products exclusively in the field of treatment, prevention, or diagnosis of any human cancer. Metagenomi, Inc. was incorporated in 2016 and is headquartered in Emeryville, California.