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MNOV
Upturn stock ratingUpturn stock rating

MediciNova Inc (MNOV)

Upturn stock ratingUpturn stock rating
$1.3
Last Close (24-hour delay)
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PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
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Upturn Advisory Summary

08/14/2025: MNOV (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

2 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $7

1 Year Target Price $7

Analysts Price Target For last 52 week
$7 Target price
52w Low $1.13
Current$1.3
52w High $2.55

Analysis of Past Performance

Type Stock
Historic Profit -20.83%
Avg. Invested days 28
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/14/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 63.76M USD
Price to earnings Ratio -
1Y Target Price 7
Price to earnings Ratio -
1Y Target Price 7
Volume (30-day avg) 2
Beta 0.35
52 Weeks Range 1.13 - 2.55
Updated Date 08/15/2025
52 Weeks Range 1.13 - 2.55
Updated Date 08/15/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.23

Earnings Date

Report Date 2025-08-13
When -
Estimate -0.095
Actual -0.07

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -13.81%
Return on Equity (TTM) -20.33%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 27378513
Price to Sales(TTM) 82.89
Enterprise Value 27378513
Price to Sales(TTM) 82.89
Enterprise Value to Revenue 38.74
Enterprise Value to EBITDA -2.65
Shares Outstanding 49046200
Shares Floating 42081189
Shares Outstanding 49046200
Shares Floating 42081189
Percent Insiders 2.98
Percent Institutions 22.02

ai summary icon Upturn AI SWOT

MediciNova Inc

stock logo

Company Overview

overview logo History and Background

MediciNova, Inc. was founded in 2000. It is a biopharmaceutical company focused on acquiring and developing novel, small-molecule therapeutics for the treatment of diseases with unmet medical needs, primarily neurological disorders, inflammatory diseases, and cancer.

business area logo Core Business Areas

  • Neurological Disorders: Development of MN-166 (ibudilast) for neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and progressive multiple sclerosis (PMS).
  • Inflammatory Diseases: Research into MN-001 (tipelukast) for idiopathic pulmonary fibrosis (IPF) and nonalcoholic steatohepatitis (NASH).
  • Cancer: Evaluation of MN-166 in various cancer indications, including glioblastoma.

leadership logo Leadership and Structure

The company is led by Yuichi Iwaki, M.D., Ph.D., President and CEO. The organizational structure includes departments for research and development, clinical trials, and corporate functions.

Top Products and Market Share

overview logo Key Offerings

  • MN-166 (Ibudilast): A phosphodiesterase inhibitor and macrophage migration inhibitory factor (MIF) inhibitor. Currently in clinical development for ALS, PMS, and other neurological indications. Market share is not applicable as it is not currently approved in any market. Competitors include Mitsubishi Tanabe Pharma (Radicava/edaravone) and Amylyx Pharmaceuticals (Relyvrio).
  • MN-001 (Tipelukast): A leukotriene receptor antagonist in development for IPF and NASH. Market share is not applicable as it is not currently approved in any market. Competitors in the IPF market include Boehringer Ingelheim (Ofev) and Roche (Esbriet).

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is highly competitive and research-intensive, focusing on the development of new therapies for various diseases. It's driven by technological advances, regulatory changes, and the increasing need for innovative treatments.

Positioning

MediciNova focuses on niche markets with significant unmet needs. Their competitive advantage lies in repurposing existing drugs for new indications, which potentially reduces development time and cost.

Total Addressable Market (TAM)

The total addressable market for neurodegenerative diseases, inflammatory diseases, and cancer is substantial, estimated to be hundreds of billions of dollars. MediciNova is positioned to capture a portion of these markets with successful drug approvals, focused on specific subtypes of diseases.

Upturn SWOT Analysis

Strengths

  • Proprietary drug candidates with potential for multiple indications
  • Experienced management team
  • Established research and development capabilities
  • Repurposing strategy potentially reduces development costs and timelines

Weaknesses

  • Limited financial resources compared to larger pharmaceutical companies
  • Dependence on successful clinical trial outcomes
  • No currently marketed products
  • High risk associated with drug development

Opportunities

  • Potential for regulatory approvals and commercialization of drug candidates
  • Partnerships with larger pharmaceutical companies
  • Expansion into new therapeutic areas
  • Orphan drug designations for rare diseases

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from other pharmaceutical companies
  • Patent expirations
  • Generic competition

Competitors and Market Share

competitor logo Key Competitors

  • AMLY
  • VRCA
  • BIIB
  • RHHBY
  • MRK

Competitive Landscape

MediciNova faces strong competition from larger, well-established pharmaceutical companies. Its advantage lies in its focus on specific unmet needs and its drug repurposing strategy, although its unproven clinical success is its weakness.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is primarily driven by progress in clinical trials and licensing agreements.

Future Projections: Future growth depends on successful clinical trial outcomes and regulatory approvals. Analyst estimates vary significantly.

Recent Initiatives: Recent initiatives include advancing clinical trials for MN-166 in ALS and PMS and MN-001 in IPF and NASH.

Summary

MediciNova is a biopharmaceutical company focusing on developing novel treatments, especially for neurological disorders and inflammatory diseases. While its drug repurposing strategy offers potential cost and time savings, the company is currently pre-revenue, relying on clinical trial success and further funding. The main threats come from regulatory hurdles, competition, and potential clinical trial failures. Success hinges on achieving positive clinical trial results and securing regulatory approvals for its key drug candidates.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • MediciNova's website
  • SEC filings
  • Analyst reports (where available)
  • Industry reports

Disclaimers:

This analysis is based on available information and is not financial advice. The biopharmaceutical industry is inherently risky, and future results may differ significantly from current expectations.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About MediciNova Inc

Exchange NASDAQ
Headquaters La Jolla, CA, United States
IPO Launch date 2005-02-08
Co-Founder, President, CEO & Chairman Dr. Yuichi Iwaki M.D., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 13
Full time employees 13

MediciNova, Inc., a biopharmaceutical company, focuses on developing novel and small molecule therapeutics for the treatment of serious diseases with unmet medical needs in the United States. The company develops MN-166 (ibudilast), an oral anti-inflammatory and neuroprotective agent in Phase 2b/3 clinical trial for treating neurological and other disorders, such as progressive multiple sclerosis, amyotrophic lateral sclerosis, chemotherapy-induced peripheral neuropathy, degenerative cervical myelopathy, glioblastoma, and substance dependence and addiction, as well as prevention of acute respiratory distress syndrome, and long COVID. It is also developing MN-001 (tipelukast), an orally bioavailable small molecule compound in Phase 2 clinical trial to treat fibrotic and other metabolic disorders, including nonalcoholic fatty liver disease and hypertriglycedemia. The company has a license agreement with Kyorin Pharmaceuticals for the development and commercialization of MN-166 and MN-001. MediciNova, Inc. was incorporated in 2000 and is headquartered in La Jolla, California.