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NewAmsterdam Pharma Company N.V. Ordinary Shares (NAMS)

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Upturn Advisory Summary
12/19/2025: NAMS (5-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $47.47
1 Year Target Price $47.47
| 5 | Strong Buy |
| 4 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 181.73% | Avg. Invested days 54 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 3.98B USD | Price to earnings Ratio - | 1Y Target Price 47.47 |
Price to earnings Ratio - | 1Y Target Price 47.47 | ||
Volume (30-day avg) 9 | Beta 0.05 | 52 Weeks Range 14.06 - 42.00 | Updated Date 12/20/2025 |
52 Weeks Range 14.06 - 42.00 | Updated Date 12/20/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.04 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -15845.69% |
Management Effectiveness
Return on Assets (TTM) -20.7% | Return on Equity (TTM) -39.94% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 3279605036 | Price to Sales(TTM) 112.96 |
Enterprise Value 3279605036 | Price to Sales(TTM) 112.96 | ||
Enterprise Value to Revenue 93.06 | Enterprise Value to EBITDA 27.63 | Shares Outstanding 113390804 | Shares Floating 62481735 |
Shares Outstanding 113390804 | Shares Floating 62481735 | ||
Percent Insiders 0.38 | Percent Institutions 106.01 |
Upturn AI SWOT
NewAmsterdam Pharma Company N.V. Ordinary Shares

Company Overview
History and Background
NewAmsterdam Pharma Company N.V. is a clinical-stage biopharmaceutical company focused on developing treatments for obesity and related metabolic diseases. It was founded with the goal of advancing novel therapeutic candidates through clinical trials and towards commercialization. Key milestones include the progression of its lead drug candidate through clinical development stages.
Core Business Areas
- Obesity Therapeutics: Development and clinical testing of novel drug candidates aimed at treating obesity and its associated metabolic disorders, such as type 2 diabetes and non-alcoholic steatohepatitis (NASH).
- Metabolic Disease Treatments: Research and development efforts targeting broader metabolic health conditions, leveraging scientific understanding of metabolic pathways.
Leadership and Structure
Information on specific leadership team members and the detailed organizational structure is typically found in official company filings (e.g., SEC filings) and investor relations materials. NewAmsterdam Pharma operates as a biopharmaceutical company with research, development, and clinical operations teams.
Top Products and Market Share
Key Offerings
- Competitors: Novo Nordisk (Wegovy, Ozempic), Eli Lilly (Mounjaro), Viking Therapeutics, Madrigal Pharmaceuticals.
- Description: A novel drug candidate currently in clinical development for the treatment of obesity and non-alcoholic steatohepatitis (NASH). The development aims to address the unmet medical needs in these areas. Specific market share data is not yet applicable as the product is in clinical stages and not yet commercialized. Key competitors in the obesity and NASH space include companies developing GLP-1 receptor agonists and other metabolic modulators.
- Product Name: NAM-001 (Obesity and NASH candidate)
Market Dynamics
Industry Overview
The biopharmaceutical industry, particularly the segment focused on obesity and metabolic diseases, is experiencing significant growth driven by rising obesity rates globally and increasing awareness of the associated health complications. Advancements in understanding metabolic pathways have led to the development of more targeted and effective treatments. The market is characterized by high R&D investment, stringent regulatory processes, and intense competition.
Positioning
NewAmsterdam Pharma is positioned as a clinical-stage biopharmaceutical company aiming to carve out a niche in the growing obesity and metabolic disease market with its novel therapeutic candidates. Its competitive advantage lies in its focused approach to developing innovative treatments for these conditions.
Total Addressable Market (TAM)
The global obesity market is substantial and projected to continue growing significantly, with estimates varying but often in the hundreds of billions of dollars. The NASH market also represents a significant opportunity. NewAmsterdam Pharma is positioned to address a portion of this TAM with its lead candidate, assuming successful clinical development and regulatory approval.
Upturn SWOT Analysis
Strengths
- Focus on a high-growth therapeutic area (obesity and metabolic diseases).
- Development of novel therapeutic candidates with potential for differentiation.
- Experienced management team with expertise in drug development.
Weaknesses
- Clinical-stage company with no approved products, leading to high R&D costs and no revenue from product sales.
- Reliance on successful completion of clinical trials and regulatory approvals.
- Limited financial resources compared to established pharmaceutical giants.
Opportunities
- Increasing global prevalence of obesity and related metabolic disorders.
- Advancements in scientific understanding of metabolic pathways.
- Potential for strategic partnerships or acquisitions by larger pharmaceutical companies.
- Unmet medical needs in the treatment of obesity and NASH.
Threats
- High failure rate in clinical trials.
- Intense competition from established pharmaceutical companies and emerging biotechs.
- Regulatory hurdles and lengthy approval processes.
- Changes in healthcare policy and reimbursement.
Competitors and Market Share
Key Competitors
- Novo Nordisk (NVO)
- Eli Lilly and Company (LLY)
- Viking Therapeutics, Inc. (VKTX)
- Madrigal Pharmaceuticals, Inc. (MDVL)
Competitive Landscape
NewAmsterdam Pharma faces a highly competitive landscape dominated by large pharmaceutical companies with established drug portfolios and significant R&D budgets. Its competitive advantage must stem from the novelty and efficacy of its drug candidates. However, it has a disadvantage in terms of resources and market presence compared to its larger rivals.
Growth Trajectory and Initiatives
Historical Growth: Historical growth for NewAmsterdam Pharma is characterized by the progression through pre-clinical and early-stage clinical development of its pipeline assets, alongside fundraising activities to support these operations.
Future Projections: Future growth projections are highly dependent on the successful clinical advancement of its drug candidates, particularly NAM-001, and subsequent regulatory approvals and market launch. Analyst projections would focus on potential peak sales estimates for its pipeline products.
Recent Initiatives: Recent initiatives likely include advancements in clinical trial phases for its lead candidates, strategic partnerships for development or commercialization, and ongoing fundraising efforts to support its operations.
Summary
NewAmsterdam Pharma is a clinical-stage biopharmaceutical company with a focused strategy on obesity and metabolic diseases. Its primary strength lies in its novel drug candidates, particularly NAM-001, targeting a high-growth market. However, it faces significant weaknesses as a pre-revenue company with high R&D costs and a strong reliance on clinical success. Key opportunities exist due to rising global obesity rates, but threats from intense competition and regulatory hurdles are substantial. Careful management of cash burn and successful clinical execution are critical for its future.
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Sources and Disclaimers
Data Sources:
- Company Investor Relations Filings (e.g., SEC filings)
- Industry Analyst Reports
- Biopharmaceutical Market Research Data
Disclaimers:
This information is for informational purposes only and does not constitute investment advice. Financial data and market information are subject to change. Actual results may differ materially from projections and forward-looking statements. Investors should conduct their own due diligence and consult with a qualified financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About NewAmsterdam Pharma Company N.V. Ordinary Shares
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2022-11-23 | CEO, President & Executive Board Member Dr. Michael Harvey Davidson FACC, Facp., M.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 68 | |
Full time employees 68 | |||
NewAmsterdam Pharma Company N.V., a late-stage biopharmaceutical company, develops therapies to enhance patient care in populations with metabolic disease. It is developing obicetrapib, an oral low-dose cholesteryl ester transfer protein (CETP) inhibitor, that is in various clinical trials as a monotherapy and a combination therapy with ezetimibe for lowering LDL-C for cardiovascular diseases. The company also develops Obicetrapib which is in Phase 2a clinical trial for Alzheimer's disease. NewAmsterdam Pharma Company N.V. is headquartered in Naarden, the Netherlands.

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