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Upturn AI Summary - About
Nuvation Bio Inc(NUVB)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for NUVB
11/10/2026: NUVB (4-star) is currently NOT-A-BUY. Pass it for now.
Nuvation Bio is a clinical-stage biopharmaceutical company focused on developing precision oncology treatments for challenging cancers. Its core strength lies in an experienced leadership team and a pipeline significantly bolstered by the acquisition of AnHeart Therapeutics. The primary growth story revolves around the successful development and potential regulatory approval of lead candidate taletrectinib. However, investors face high risks, including the binary nature of clinical outcomes, heavy competition from large pharmaceutical firms, and the need for continuous funding. The stock is best suited for risk-tolerant investors looking for exposure to biotechnology innovation, with critical developments in trial data and regulatory progress to monitor closely.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high growth potential linked to clinical success but involves substantial development risk. |
| Momentum investor | Strong fit while signal remains positive | Momentum may build around significant clinical trial data announcements. |
| Value investor | Weak fit | The lack of earnings and revenue makes standard value metrics inapplicable. |
| Dividend investor | Weak fit | The company does not pay dividends and focuses entirely on cash-intensive R&D. |
| Low-risk investor | Weak fit | Clinical-stage biotech stocks are inherently high-risk due to binary clinical outcomes. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | The stock price is highly sensitive to news regarding clinical trial outcomes. |
| Valuation risk | High | Valuation is speculative and based on the future probability of drug approval. |
| Competition risk (Major Pharma) | High | The company competes with massive organizations for market share and physician adoption. |
| Business quality | Medium | The company is early-stage, meaning the business model is not yet proven in a commercial context. |
| Dividend income | Low / none | There is no income component to the investment. |
| Execution risk | High | Failure to meet clinical endpoints can lead to significant loss of value. |
Price Behavior
Rolling Over
The price momentum is slowing down and beginning to turn downward.
Highly Choppy
The stock has experienced frequent, large price swings that make its near-term movement less predictable.
Analysis of Past Performance
Type Stock | Historic Profit 103.04% | Avg. Invested days 42 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  5.0 |
| Profits based on simulation | Last Close 11/10/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.54B USD | Price to earnings Ratio - | 1Y Target Price 12.45 |
Price to earnings Ratio - | 1Y Target Price 12.45 | ||
Volume (30-day avg) 5.7M shares | Beta 1.73 | 52 Weeks Range 3.98 - 9.75 | Updated Date 11/10/2026 |
52 Weeks Range 3.98 - 9.75 | Updated Date 11/10/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.39 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Clinical-Stage Oncology Pipeline | Research, development, and upcoming potential licensing of oncology assets like taletrectinib. | Nuvation Bio does not currently sell products; it makes money by advancing drugs that may eventually be licensed or sold to larger companies. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Valuation
Trailing PE - | Forward PE - | Enterprise Value 1.11B | Price to Sales(TTM) 7.61 |
Enterprise Value 1.11B | Price to Sales(TTM) 7.61 | ||
Enterprise Value to Revenue 5.48 | Enterprise Value to EBITDA 2.23 | Shares Outstanding 352.02M | Shares Floating 265.54M |
Shares Outstanding 352.02M | Shares Floating 265.54M | ||
Percent Insiders 17.09 | Percent Institutions 68.57 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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