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Upturn AI Summary - About
Olema Pharmaceuticals Inc(OLMA)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for OLMA
10/20/2026: OLMA (1-star) is currently NOT-A-BUY. Pass it for now.
Olema Pharmaceuticals is a clinical-stage biotechnology company focused on developing targeted oral therapies for HR+ breast cancer. Its main strength lies in its specialized research platform and its primary clinical asset, Palazestrant. The core investment story centers on the potential for this drug to offer a more effective treatment option, which could lead to acquisition interest or high growth upon success. However, investors must consider the significant risks of clinical trial failure, intense competition from well-capitalized pharmaceutical giants, and the need for ongoing funding. This stock is best suited for growth-oriented investors with a high risk tolerance who are willing to monitor binary clinical data milestones.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | Olema offers high-risk, high-reward potential based on clinical trial success rather than proven growth metrics. |
| Momentum investor | Mixed fit | The stock can experience significant moves around clinical data, making it suitable only for those monitoring positive clinical triggers. |
| Value investor | Weak fit | The company lacks current earnings, revenue, and assets, making standard value metrics inapplicable. |
| Dividend investor | Weak fit | Olema does not pay a dividend and focuses entirely on cash-intensive R&D. |
| Low-risk investor | Weak fit | Clinical-stage biotech stocks carry extreme volatility and risk of total capital loss if products fail to reach the market. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | The stock is highly sensitive to binary clinical trial outcomes and biotech sector sentiment. |
| Valuation risk | High | Valuations are based on speculative long-term success rather than current fundamentals. |
| Competition risk (Large Pharma) | High | Established players have significantly more resources to outspend and out-market smaller biotech firms. |
| Business quality | Medium | The company is a single-product candidate firm, which inherently carries more risk than diversified operators. |
| Dividend income | Low / none | Investors should not expect any income from this stock. |
| Execution risk | High | Successfully taking a drug through complex regulatory approval processes is inherently difficult and uncertain. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Highly Choppy
The stock has experienced frequent, large price swings that make its near-term movement less predictable.
Analysis of Past Performance
Type Stock | Historic Profit -20.5% | Avg. Invested days 21 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 10/20/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 622.11M USD | Price to earnings Ratio - | 1Y Target Price 36.5 |
Price to earnings Ratio - | 1Y Target Price 36.5 | ||
Volume (30-day avg) 1.3M shares | Beta 2.01 | 52 Weeks Range 6.48 - 36.26 | Updated Date 10/20/2026 |
52 Weeks Range 6.48 - 36.26 | Updated Date 10/20/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.12 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Clinical Development | Research, development, and clinical trial activities for Palazestrant. | The company currently spends money to develop products and does not yet generate revenue from sales. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 315.19M | Price to Sales(TTM) - |
Enterprise Value 315.19M | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -3.33 | Shares Outstanding 87.50M | Shares Floating 59.24M |
Shares Outstanding 87.50M | Shares Floating 59.24M | ||
Percent Insiders 1.76 | Percent Institutions 119.73 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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