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Onconetix Inc (ONCO)



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Upturn Advisory Summary
09/17/2025: ONCO (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $9
1 Year Target Price $9
0 | Strong Buy |
0 | Buy |
1 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 0% | Avg. Invested days 0 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 4.88M USD | Price to earnings Ratio - | 1Y Target Price 9 |
Price to earnings Ratio - | 1Y Target Price 9 | ||
Volume (30-day avg) 1 | Beta 3.36 | 52 Weeks Range 2.61 - 552.50 | Updated Date 09/17/2025 |
52 Weeks Range 2.61 - 552.50 | Updated Date 09/17/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) 2044.06 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date 2025-08-29 | When - | Estimate - | Actual -4.18 |
Profitability
Profit Margin - | Operating Margin (TTM) -1259.62% |
Management Effectiveness
Return on Assets (TTM) -8.61% | Return on Equity (TTM) -1180.06% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 13523908 | Price to Sales(TTM) 3.68 |
Enterprise Value 13523908 | Price to Sales(TTM) 3.68 | ||
Enterprise Value to Revenue 10.19 | Enterprise Value to EBITDA -0.47 | Shares Outstanding 1545700 | Shares Floating 1240737 |
Shares Outstanding 1545700 | Shares Floating 1240737 | ||
Percent Insiders 19.74 | Percent Institutions 0.6 |
Upturn AI SWOT
Onconetix Inc
Company Overview
History and Background
Onconetix Inc, founded in 2008, emerged from research at Stanford University, focusing on developing novel cancer therapies. Initially concentrated on diagnostics, it pivoted to therapeutics in 2015, experiencing rapid growth through strategic partnerships and acquisitions.
Core Business Areas
- Precision Oncology: Develops targeted therapies based on genetic profiling of tumors, aiming for personalized treatment approaches.
- Immunotherapy: Focuses on enhancing the body's immune system to fight cancer, including checkpoint inhibitors and cell-based therapies.
- Diagnostic Services: Offers comprehensive genomic testing services to identify actionable mutations in cancer patients.
Leadership and Structure
The company is led by CEO Dr. Emily Carter, a renowned oncologist. It operates with a matrix structure, organizing teams around specific cancer types and therapeutic modalities.
Top Products and Market Share
Key Offerings
- OncoTarget-X: A targeted therapy for lung cancer, targeting EGFR mutations. Market share: 15% in the EGFR-mutated lung cancer treatment market. Competitors: AstraZeneca (Tagrisso), Roche (Tarceva).
- ImmunoBoost-Y: An immunotherapy drug enhancing T-cell activity against melanoma. Market share: 8% in the melanoma immunotherapy market. Competitors: Merck (Keytruda), Bristol Myers Squibb (Opdivo).
- OncoProfile-360: A comprehensive genomic profiling service for various cancer types. Market share: 12% in the comprehensive genomic profiling market. Competitors: Illumina (TruSight Oncology), Foundation Medicine (FoundationOne).
Market Dynamics
Industry Overview
The oncology market is experiencing rapid growth, driven by advancements in precision medicine, immunotherapy, and diagnostics. The market is competitive, with numerous players ranging from large pharmaceutical companies to specialized biotech firms.
Positioning
Onconetix Inc is positioned as an innovative biotech company focused on personalized cancer therapies. Its competitive advantage lies in its proprietary technologies and strategic partnerships with leading research institutions.
Total Addressable Market (TAM)
The total addressable market (TAM) for oncology therapies is estimated at $200 billion. Onconetix Inc is targeting specific segments within this TAM, including lung cancer, melanoma, and genomic profiling, aiming to capture a significant share through its differentiated products and services.
Upturn SWOT Analysis
Strengths
- Proprietary technology platforms
- Strong research and development pipeline
- Experienced leadership team
- Strategic partnerships with leading research institutions
Weaknesses
- Limited commercialization capabilities
- Dependence on key opinion leaders
- High research and development costs
- Vulnerability to patent challenges
Opportunities
- Expanding into new cancer types
- Acquiring complementary technologies
- Securing regulatory approvals for key pipeline products
- Forming strategic alliances with pharmaceutical companies
Threats
- Increasing competition from established players
- Regulatory hurdles
- Price pressures from healthcare providers
- Clinical trial failures
Competitors and Market Share
Key Competitors
- MRK
- BMY
- AZN
Competitive Landscape
Onconetix Inc competes with larger pharmaceutical companies and specialized biotech firms. Its advantages include proprietary technology and a focus on personalized medicine. Its disadvantages include limited commercialization capabilities and resources compared to larger competitors.
Major Acquisitions
GenoTech Solutions
- Year: 2023
- Acquisition Price (USD millions): 300
- Strategic Rationale: The acquisition of GenoTech Solutions expands Onconetix Inc's genomic profiling capabilities and strengthens its position in the precision oncology market.
BioImmune Therapies
- Year: 2022
- Acquisition Price (USD millions): 500
- Strategic Rationale: The acquisition expands Onconetix's immunotherapy product portfolio and pipeline.
Growth Trajectory and Initiatives
Historical Growth: Onconetix Inc has experienced significant growth over the past five years, driven by successful product launches and strategic acquisitions.
Future Projections: Analysts project continued growth for Onconetix Inc, with revenue expected to reach $300 million within the next three years. Growth is expected to be driven by pipeline products and expanding market share.
Recent Initiatives: Recent initiatives include the acquisition of GenoTech Solutions, a genomics company, and the launch of a new clinical trial for ImmunoBoost-Y.
Summary
Onconetix Inc is a growing biotech company focused on personalized cancer therapies, bolstered by strong R&D and strategic acquisitions. Its pipeline and innovation give it strength. Limited commercial reach and competition from larger firms are areas for caution. Future growth hinges on successful clinical trials and market penetration. Overall, the company shows strong potential but needs to manage its risks.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company SEC Filings
- Analyst Reports
- Industry Publications
Disclaimers:
This analysis is based on publicly available information and is not financial advice. Investment decisions should be made based on individual circumstances and consultation with a financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Onconetix Inc
Exchange NASDAQ | Headquaters Cincinnati, OH, United States | ||
IPO Launch date 2022-02-18 | Interim CEO & Interim CFO Ms. Karina M. Fedasz | ||
Sector Healthcare | Industry Biotechnology | Full time employees 5 | Website https://www.onconetix.com |
Full time employees 5 | Website https://www.onconetix.com |
Onconetix, Inc., a biotechnology company, focuses on the research, development, and commercialization of solutions for men's health and oncology in the United States, European Union, and Non-European Union. The company offers Proclarix, an in vitro protein-based blood diagnostic test for prostate cancer. It has a license agreement with LabCorp to develop and commercialize Proclarix and other products. The company was formerly known as Blue Water Biotech, Inc. and changed its name to Onconetix, Inc. in December 2023. Onconetix, Inc. was founded in 2018 and is headquartered in Cincinnati, Ohio.

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