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Opko Health Inc (OPK)

Upturn stock ratingUpturn stock rating
$1.35
Last Close (24-hour delay)
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PASS
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  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Time period over
  • ALL
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Upturn Advisory Summary

08/14/2025: OPK (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

7 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $3.62

1 Year Target Price $3.62

Analysts Price Target For last 52 week
$3.62 Target price
52w Low $1.11
Current$1.35
52w High $2.04

Analysis of Past Performance

Type Stock
Historic Profit -47.93%
Avg. Invested days 34
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/14/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.07B USD
Price to earnings Ratio -
1Y Target Price 3.62
Price to earnings Ratio -
1Y Target Price 3.62
Volume (30-day avg) 7
Beta 1.19
52 Weeks Range 1.11 - 2.04
Updated Date 08/15/2025
52 Weeks Range 1.11 - 2.04
Updated Date 08/15/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.26

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date 2025-07-31
When -
Estimate -0.1133
Actual -0.19

Profitability

Profit Margin -26.68%
Operating Margin (TTM) -38.25%

Management Effectiveness

Return on Assets (TTM) -8.46%
Return on Equity (TTM) -13.16%

Valuation

Trailing PE -
Forward PE 64.52
Enterprise Value 1195628753
Price to Sales(TTM) 1.61
Enterprise Value 1195628753
Price to Sales(TTM) 1.61
Enterprise Value to Revenue 1.8
Enterprise Value to EBITDA 20.05
Shares Outstanding 793782976
Shares Floating 376110157
Shares Outstanding 793782976
Shares Floating 376110157
Percent Insiders 46.77
Percent Institutions 31.96

ai summary icon Upturn AI SWOT

Opko Health Inc

stock logo

Company Overview

overview logo History and Background

Opko Health Inc. was founded in 1991. It is a diversified healthcare company that seeks to establish industry-leading positions in diagnostics, pharmaceuticals, and biologics. Over time, it has expanded its product portfolio through acquisitions and internal development.

business area logo Core Business Areas

  • Diagnostics: Development and commercialization of molecular diagnostics and point-of-care testing platforms.
  • Pharmaceuticals: Development and commercialization of pharmaceutical products, including Rayaldee for secondary hyperparathyroidism.
  • Biologics: Development of biologic products, including growth hormone and Factor VIIa.

leadership logo Leadership and Structure

Dr. Phillip Frost is the Chairman and CEO. The company has a standard corporate structure with departments focused on R&D, manufacturing, sales, and marketing.

Top Products and Market Share

overview logo Key Offerings

  • Rayaldee: A vitamin D prohormone used to treat secondary hyperparathyroidism in adults with chronic kidney disease. Market share is relatively small compared to larger pharmaceutical companies. Competitors include vitamin D supplements and other treatments for SHPT like calcimimetics (Sensipar by Amgen).
  • BioReference Laboratories: Provides diagnostic testing services. Competitors include Quest Diagnostics (DGX) and Laboratory Corporation of America Holdings (LH).

Market Dynamics

industry overview logo Industry Overview

The healthcare industry is characterized by increasing demand for diagnostics, pharmaceuticals, and biologics due to aging populations and advances in medical technology.

Positioning

Opko Health Inc. operates in a competitive market with established players. Its competitive advantage lies in its diversified product portfolio and innovative technologies.

Total Addressable Market (TAM)

The global diagnostics, pharmaceuticals, and biologics market is estimated to be worth billions of dollars. Opko Health Inc. is positioned to capture a portion of this TAM through its products and services.

Upturn SWOT Analysis

Strengths

  • Diversified product portfolio
  • Innovative technologies
  • Experienced leadership
  • BioReference Laboratories strong market presence

Weaknesses

  • High debt levels
  • History of net losses
  • Regulatory risks
  • Dependence on key products

Opportunities

  • Expanding market for diagnostics
  • Growing demand for pharmaceuticals
  • Strategic partnerships
  • New product launches

Threats

  • Competition from larger companies
  • Pricing pressures
  • Patent expirations
  • Economic downturns

Competitors and Market Share

competitor logo Key Competitors

  • DGX
  • LH
  • AMGN

Competitive Landscape

Opko Health Inc. faces strong competition from larger, more established companies with greater resources.

Major Acquisitions

BioReference Laboratories

  • Year: 2015
  • Acquisition Price (USD millions): 1470
  • Strategic Rationale: Expanded Opko's diagnostic testing capabilities.

Growth Trajectory and Initiatives

Historical Growth: Growth has been uneven, driven by acquisitions and product development.

Future Projections: Analyst estimates vary, but project modest growth in revenue over the next few years.

Recent Initiatives: Focus on expanding diagnostic testing services and commercializing new pharmaceutical products.

Summary

Opko Health is a diversified healthcare company with exposure to diagnostics, pharmaceuticals and biologics, but with large debt and a history of net losses. BioReference Labratories provides a solid market presence. It faces strong competition and regulatory risk. It's future depends on successful commercialization of new products and effective debt management.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company SEC Filings
  • Analyst Reports
  • Company Website

Disclaimers:

The information provided is for informational purposes only and does not constitute financial advice. Investors should conduct their own due diligence before making any investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Opko Health Inc

Exchange NASDAQ
Headquaters Miami, FL, United States
IPO Launch date 1995-11-02
Chairman & CEO Dr. Phillip Frost M.D., Ph.D.
Sector Healthcare
Industry Diagnostics & Research
Full time employees 2997
Full time employees 2997

OPKO Health, Inc., a healthcare company, engages in the diagnostics and pharmaceuticals businesses in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company's Diagnostics segment operates BioReference Laboratories that offer laboratory testing services for the detection, diagnosis, evaluation, monitoring, and treatment of diseases, including esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare to physician offices, clinics, hospitals, employers, and governmental units; and 4Kscore prostate cancer test services. Its Pharmaceutical segment offers Rayaldee to treat secondary hyperparathyroidism in adults with stage 3 or 4 chronic kidney disease, and vitamin D insufficiency. This segment also develops multi-specific immune therapies focused on oncology, immunology, and infectious diseases; OPK88004, an orally administered selective androgen receptor modulator; OPK88003, a once-weekly administered peptide for the treatment of type 2 diabetes and related obesity; Somatrogon (hGH-CTP), a once-weekly human growth hormone injection; and Factor VIIa-CTP, a novel long-acting coagulation factor to treat hemophilia. In addition, it develops and commercializes longer-acting proprietary versions of already approved therapeutic proteins or peptides; develops and produces specialty APIs; develops, manufactures, markets, and sells pharmaceutical, nutraceutical, veterinary, and ophthalmic products; commercializes food supplements and over the counter products; manufactures and sells products primarily in the generics market; and markets, distributes, and sells pharmaceutical products for a range of indications, including cardiovascular products, vaccines, antibiotics, gastro-intestinal products, hormones, and others. The company also operates pharmaceutical platforms in Spain, Ireland, Chile, and Mexico. OPKO Health, Inc. was founded in 2007 and is headquartered in Miami, Florida.