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Palisade Bio Inc(PALI)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for PALI
11/09/2026: PALI (1-star) is currently NOT-A-BUY. Pass it for now.
Palisade Bio Inc is a clinical-stage biotechnology company focused on developing novel therapies for gastrointestinal and innate immune system disorders. Its primary investment story hinges on the success of its lead candidate, LB1148, in addressing post-operative complications. While the company possesses a specialized technology platform, it currently lacks commercial revenue and faces the significant execution and financial risks inherent in drug development. Potential investors should note that the stock is highly speculative and may experience significant volatility related to clinical trial data and equity financing needs. The company is best suited for high-risk investors who closely monitor regulatory updates and clinical trial progress.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Weak fit | The company is in an early clinical stage and lacks a proven commercial growth trajectory. |
| Momentum investor | Weak fit | The stock often lacks consistent positive price momentum required for trend-following strategies. |
| Value investor | Weak fit | As a loss-making biotech, there are no earnings or cash flow metrics to justify a value-based entry. |
| Dividend investor | Weak fit | The company does not pay dividends and requires all cash for operational survival. |
| Low-risk investor | Weak fit | Clinical-stage biotechnology stocks carry inherent high volatility and risk of total capital loss. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | The stock is susceptible to large swings based on clinical trial news and financing events. |
| Valuation risk | High | Valuations are speculative and highly sensitive to subjective R&D success probabilities. |
| Competition risk (Pharmaceutical competition) | High | Well-capitalized competitors can outspend and outmaneuver the company in clinical development. |
| Business quality | Medium | The company is pre-revenue, making it a high-risk entity compared to established, profitable firms. |
| Dividend income | Low / none | There is no income generation for investors from this holding. |
| Execution risk | High | Failure to successfully navigate regulatory hurdles or complete trials would jeopardize the business. |
Price Behavior
Downtrend
The stock has experienced a sustained decline in price over recent periods.
Highly Choppy
The stock has experienced frequent, large price swings that make its near-term movement less predictable.
Analysis of Past Performance
Type Stock | Historic Profit -37.94% | Avg. Invested days 16 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  1.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/09/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 196.93M USD | Price to earnings Ratio 1.88 | 1Y Target Price 9.8 |
Price to earnings Ratio 1.88 | 1Y Target Price 9.8 | ||
Volume (30-day avg) 3.4M shares | Beta 1.62 | 52 Weeks Range 1.08 - 2.86 | Updated Date 11/08/2026 |
52 Weeks Range 1.08 - 2.86 | Updated Date 11/08/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) 0.6 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Therapeutic Development | Clinical trial assets such as LB1148. | The company currently makes no money; it spends cash to test drugs that it hopes to sell or license later. |
Valuation
Trailing PE 1.88 | Forward PE - | Enterprise Value 64.71M | Price to Sales(TTM) 393.85 |
Enterprise Value 64.71M | Price to Sales(TTM) 393.85 | ||
Enterprise Value to Revenue 129.42 | Enterprise Value to EBITDA 0.57 | Shares Outstanding 174.27M | Shares Floating 135.43M |
Shares Outstanding 174.27M | Shares Floating 135.43M | ||
Percent Insiders 4.61 | Percent Institutions 105 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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