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PDS Biotechnology Corp (PDSB)



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Upturn Advisory Summary
04/22/2025: PDSB (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -56.05% | Avg. Invested days 23 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 59.92M USD | Price to earnings Ratio - | 1Y Target Price 7.5 |
Price to earnings Ratio - | 1Y Target Price 7.5 | ||
Volume (30-day avg) 306305 | Beta 1.49 | 52 Weeks Range 0.85 - 4.42 | Updated Date 04/25/2025 |
52 Weeks Range 0.85 - 4.42 | Updated Date 04/25/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.03 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -43.34% | Return on Equity (TTM) -166.65% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 40060659 | Price to Sales(TTM) - |
Enterprise Value 40060659 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.58 | Shares Outstanding 45395900 | Shares Floating 43980408 |
Shares Outstanding 45395900 | Shares Floating 43980408 | ||
Percent Insiders 3.05 | Percent Institutions 9.52 |
Analyst Ratings
Rating 4.8 | Target Price 11.5 | Buy 1 | Strong Buy 4 |
Buy 1 | Strong Buy 4 | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
PDS Biotechnology Corp

Company Overview
History and Background
PDS Biotechnology Corp is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies for cancer and infectious diseases. Founded in 2006, it has progressed from initial research to clinical trials, focusing on its Versamuneu00ae and Infectimuneu2122 technology platforms.
Core Business Areas
- Versamuneu00ae Platform: This platform focuses on generating potent T-cell immunity against cancer targets. It delivers tumor-associated antigens to antigen-presenting cells to stimulate a strong immune response.
- Infectimuneu2122 Platform: This platform is designed to induce T-cell immunity against infectious diseases.
Leadership and Structure
The leadership team consists of experienced executives in the biotechnology and pharmaceutical industries, with expertise in drug development, clinical trials, and regulatory affairs. The organizational structure is typical of a clinical-stage biotech, with departments focused on R&D, clinical operations, and business development.
Top Products and Market Share
Key Offerings
- PDS0101: A Versamuneu00ae-based immunotherapy being developed for HPV-associated cancers, including cervical, head and neck, and anal cancers. Currently in Phase 2 and Phase 3 clinical trials. Competitors include companies developing similar cancer immunotherapies, such as Merck (Keytruda) and Bristol Myers Squibb (Opdivo). Market share data is currently not available for a pre-market product. Revenue is $0.
- PDS0203: An Infectimuneu2122-based immunotherapy being developed for influenza. Currently in preclinical. Competitors include companies that produce seasonal flu vaccines, such as Sanofi, GSK, and CSL Seqirus. Market share data is currently not available for a pre-market product. Revenue is $0.
Market Dynamics
Industry Overview
The immunotherapy market is experiencing significant growth, driven by advancements in cancer research and the development of novel therapeutic approaches. Competition is high, with numerous companies developing new immunotherapies.
Positioning
PDS Biotechnology Corp is positioned as a developer of targeted immunotherapies, with its Versamuneu00ae platform offering a unique approach to generating potent T-cell responses. Its competitive advantage lies in its technology's ability to induce strong and durable immune responses.
Total Addressable Market (TAM)
The global cancer immunotherapy market is projected to reach hundreds of billions of dollars. PDS Biotech is positioned to capture a portion of this market by developing effective therapies for HPV-associated cancers and other indications.
Upturn SWOT Analysis
Strengths
- Novel Versamuneu00ae and Infectimuneu2122 technology platforms
- Promising preclinical and clinical data for PDS0101
- Experienced management team
- Strong intellectual property portfolio
Weaknesses
- Limited financial resources compared to larger pharmaceutical companies
- Dependence on clinical trial success
- Currently no products on the market generating revenue
Opportunities
- Expansion into new cancer indications
- Partnerships with larger pharmaceutical companies
- Positive clinical trial results leading to regulatory approval
- Further development of the Infectimuneu2122 platform
Threats
- Clinical trial failures
- Competition from other immunotherapy developers
- Regulatory hurdles
- Market access challenges
Competitors and Market Share
Key Competitors
- MRK
- BMY
- GILD
Competitive Landscape
PDS Biotechnology Corp faces intense competition from established pharmaceutical companies and other biotechnology companies developing immunotherapies. Its advantage lies in its innovative technology platforms and targeted approach. Its disadvantage is limited resources compared to larger players.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: The company's growth has been primarily driven by the advancement of its clinical programs and preclinical pipeline. Historical data would reflect R&D expenditure growth not revenue growth.
Future Projections: Future growth is dependent on the successful completion of clinical trials and potential regulatory approvals for PDS0101 and other pipeline candidates. Analyst estimates vary widely depending on clinical trial outcomes.
Recent Initiatives: Recent initiatives include progressing PDS0101 through Phase 2 and Phase 3 clinical trials, expanding the pipeline with new programs, and strengthening partnerships with key opinion leaders.
Summary
PDS Biotechnology Corp is a clinical-stage biopharmaceutical company with promising Versamuneu00ae technology. Success hinges on clinical trial outcomes for PDS0101 and further pipeline development. It faces challenges related to funding, regulatory approvals, and competition from larger pharmaceutical companies. Positive results could lead to significant growth, while setbacks could negatively impact its valuation.
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Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports
- ClinicalTrials.gov
Disclaimers:
This analysis is based on publicly available information and should not be considered investment advice. The biotechnology industry is inherently risky, and past performance is not indicative of future results.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About PDS Biotechnology Corp
Exchange NASDAQ | Headquaters Princeton, NJ, United States | ||
IPO Launch date 2015-10-01 | President, CEO & Director Dr. Frank K. Bedu-Addo Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 24 | Website https://www.pdsbiotech.com |
Full time employees 24 | Website https://www.pdsbiotech.com |
PDS Biotechnology Corporation, a clinical-stage biopharmaceutical company, developing a pipeline of targeted cancer immunotherapies. The company's lead product candidate is Versamune HPV, which is in phase II clinical trial for the treatment of head and neck, cervical, anal, vaginal, vulvar, and penile cancers. It also develops various product candidates, which are in preclinical trials, including PDS0102, an investigational immunotherapy utilizing tumor-associated and immunologically active T cell receptor gamma alternate reading framed protein for treating acute myeloid leukemia, prostate, and breast cancer; and PDS0103 for ovarian, breast, colorectal, and lung cancers. In addition, the company is developing PDS01ADC, a novel investigational Interleukin 12 fused antibody-drug conjugate, tumor-targeting interleukin 12 immune-cytokine that enhances the proliferation, potency, and longevity of T cells in the tumor microenvironment. Further, the company provides PDS0202, a novel investigational influenza vaccine that protects against the strains predicted to be prevalent in an upcoming flu season. It has a license and collaboration agreements with National Institutes of Health, Merck Eprova AG, The U.S. Department of Health and Human Services, and MSD International GmbH. PDS Biotechnology Corporation was founded in 2005 and is based in Princeton, New Jersey.
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