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Phathom Pharmaceuticals Inc (PHAT)

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Upturn Advisory Summary
12/29/2025: PHAT (2-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $22.9
1 Year Target Price $22.9
| 6 | Strong Buy |
| 2 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 49.11% | Avg. Invested days 38 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.25B USD | Price to earnings Ratio - | 1Y Target Price 22.9 |
Price to earnings Ratio - | 1Y Target Price 22.9 | ||
Volume (30-day avg) 9 | Beta 0.43 | 52 Weeks Range 2.21 - 18.31 | Updated Date 12/28/2025 |
52 Weeks Range 2.21 - 18.31 | Updated Date 12/28/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -3.76 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -186.53% | Operating Margin (TTM) -30.85% |
Management Effectiveness
Return on Assets (TTM) -42.54% | Return on Equity (TTM) -3489% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 1323842006 | Price to Sales(TTM) 8.49 |
Enterprise Value 1323842006 | Price to Sales(TTM) 8.49 | ||
Enterprise Value to Revenue 8.99 | Enterprise Value to EBITDA -2.2 | Shares Outstanding 71138440 | Shares Floating 50254315 |
Shares Outstanding 71138440 | Shares Floating 50254315 | ||
Percent Insiders 4.57 | Percent Institutions 87.81 |
Upturn AI SWOT
Phathom Pharmaceuticals Inc

Company Overview
History and Background
Phathom Pharmaceuticals Inc. is a biopharmaceutical company focused on the development and commercialization of novel treatments for gastrointestinal (GI) and autoimmune diseases. Founded in 2017, it emerged with a strategic vision to address unmet medical needs in these areas. A significant milestone was its initial public offering (IPO) in 2021, which provided capital for advancing its pipeline. The company's evolution has been characterized by strategic partnerships and the progression of its lead candidates through clinical development.
Core Business Areas
- Gastrointestinal Diseases: Development of novel therapeutics targeting various gastrointestinal disorders, including inflammatory bowel disease (IBD) and other GI-related conditions. The focus is on innovative mechanisms of action to improve patient outcomes.
- Autoimmune Diseases: Research and development of treatments for autoimmune diseases, aiming to modulate the immune system to restore balance and reduce disease activity. This segment leverages Phathom's scientific expertise in immunology.
Leadership and Structure
Phathom Pharmaceuticals Inc. is led by a seasoned management team with extensive experience in the pharmaceutical industry. Specific details on individual leaders and the precise organizational chart are typically found in company filings and investor relations materials. The company operates as a publicly traded entity, adhering to corporate governance standards.
Top Products and Market Share
Key Offerings
- Product Name 1: Phathom's pipeline includes investigational drug candidates for GI and autoimmune diseases. Specific product names and their development stages are proprietary and subject to change. As the company is in the development phase, there is no current market share or revenue from approved products. Competitors vary based on the specific disease indication and stage of development, potentially including major pharmaceutical companies with established GI and immunology portfolios.
Market Dynamics
Industry Overview
The biopharmaceutical industry, particularly in the areas of GI and autoimmune diseases, is characterized by high R&D costs, long development timelines, and significant regulatory hurdles. It is driven by scientific innovation, unmet medical needs, and the potential for substantial returns on successful drug development. The market is competitive, with both established players and emerging biotechs vying for market share.
Positioning
Phathom Pharmaceuticals Inc. is positioned as an emerging biopharmaceutical company focused on developing innovative therapies for underserved patient populations in GI and autoimmune diseases. Its competitive advantage lies in its scientific platform, its pipeline of novel drug candidates, and its strategic approach to clinical development.
Total Addressable Market (TAM)
The TAM for GI and autoimmune diseases is substantial, measured in tens of billions of dollars globally, reflecting the high prevalence and chronic nature of these conditions. Phathom Pharmaceuticals Inc. aims to capture a portion of this market by developing differentiated therapies that offer significant clinical benefits over existing treatments.
Upturn SWOT Analysis
Strengths
- Innovative pipeline of novel drug candidates.
- Experienced management team with biopharmaceutical expertise.
- Focus on significant unmet medical needs in GI and autoimmune diseases.
- Potential for strong intellectual property protection.
Weaknesses
- As a clinical-stage company, it has no approved products and thus no revenue.
- High reliance on successful clinical trial outcomes and regulatory approvals.
- Significant capital requirements for R&D and commercialization.
- Limited brand recognition and market presence compared to larger competitors.
Opportunities
- Advancement of pipeline candidates through clinical trials.
- Strategic partnerships and collaborations with larger pharmaceutical companies.
- Expansion into new therapeutic areas within GI and autoimmune diseases.
- Growing demand for effective treatments for chronic diseases.
Threats
- Clinical trial failures or delays.
- Intensifying competition from other biopharmaceutical companies.
- Regulatory challenges and changes in healthcare policy.
- Patent expirations of competing drugs and the emergence of generics.
- Economic downturns affecting R&D funding and market access.
Competitors and Market Share
Key Competitors
- Gilead Sciences (GILD)
- AbbVie (ABBV)
- Pfizer (PFE)
- Bristol Myers Squibb (BMY)
Competitive Landscape
Phathom Pharmaceuticals Inc. faces competition from large, established pharmaceutical companies with extensive R&D capabilities, existing product portfolios, and significant market presence in GI and autoimmune diseases. Phathom's advantage lies in its potential to develop novel, differentiated therapies that address unmet needs, potentially offering improved efficacy or safety profiles compared to existing treatments.
Growth Trajectory and Initiatives
Historical Growth: Phathom Pharmaceuticals Inc.'s historical growth has been characterized by its establishment, progression of its pipeline candidates into clinical development, and its successful initial public offering. Its growth is measured by scientific milestones and the expansion of its research and development activities.
Future Projections: Future growth projections are heavily dependent on the successful clinical development and regulatory approval of its lead drug candidates. Analyst estimates would focus on potential market penetration and peak sales of its future products. Significant growth is anticipated if its pipeline yields successful commercialized therapies.
Recent Initiatives: Recent initiatives likely include ongoing clinical trial activities for its lead compounds, potential strategic partnerships to advance development or commercialization, and efforts to manage its capital efficiently to support its R&D programs.
Summary
Phathom Pharmaceuticals Inc. is a promising, yet early-stage, biopharmaceutical company with a clear focus on unmet needs in gastrointestinal and autoimmune diseases. Its strengths lie in its innovative pipeline and experienced team, but its primary weakness is the absence of revenue and the inherent risks of clinical development. The company has significant opportunities in advancing its candidates and forging partnerships, but must navigate intense competition and regulatory hurdles. Its future success hinges entirely on the successful translation of its research into approved and marketable therapies.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company SEC Filings (e.g., 10-K, 10-Q)
- Financial News Outlets (e.g., Bloomberg, Reuters, Wall Street Journal)
- Industry Research Reports
- Company Investor Relations Websites
Disclaimers:
This analysis is based on publicly available information and is for informational purposes only. It does not constitute financial advice. Investment decisions should be made in consultation with a qualified financial advisor. Market share data for clinical-stage companies is often estimates or projections and may not reflect actual market penetration.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Phathom Pharmaceuticals Inc
Exchange NASDAQ | Headquaters Florham Park, NJ, United States | ||
IPO Launch date 2019-10-25 | CEO, President & Director Mr. Steven L. Basta M.B.A. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 427 | Website https://www.phathompharma.com |
Full time employees 427 | Website https://www.phathompharma.com | ||
Phathom Pharmaceuticals, Inc., a biopharmaceutical company, focuses on developing and commercializing treatments for gastrointestinal diseases. It develops VOQUEZNA, which has completed Phase III clinical trials for the treatment of erosive gastroesophageal reflux disease (GERD) and related heartburn in adults; and VOQUEZNA Triple Pak and VOQUEZNA Dual Pak that have completed Phase III clinical trials for treating Helicobacter pylori, as well as VOQUEZNA and vonoprazan for the treatment of heartburn associated with non-erosive GERD and eosinophilic esophagitis in adults and adolescents. The company was incorporated in 2018 and is headquartered in Florham Park, New Jersey.

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