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PRAX
Upturn stock ratingUpturn stock rating

Praxis Precision Medicines Inc (PRAX)

Upturn stock ratingUpturn stock rating
$38.31
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

05/22/2025: PRAX (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

ratingratingratingratingrating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -17.65%
Avg. Invested days 34
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 05/22/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 767.50M USD
Price to earnings Ratio -
1Y Target Price 97.67
Price to earnings Ratio -
1Y Target Price 97.67
Volume (30-day avg) 407116
Beta 2.67
52 Weeks Range 26.70 - 91.83
Updated Date 05/22/2025
52 Weeks Range 26.70 - 91.83
Updated Date 05/22/2025
Dividends yield (FY) -
Basic EPS (TTM) -10.66

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date 2025-05-12
When Before Market
Estimate -2.07
Actual -3.29

Profitability

Profit Margin -
Operating Margin (TTM) -2868.84%

Management Effectiveness

Return on Assets (TTM) -39.95%
Return on Equity (TTM) -63.56%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 440578241
Price to Sales(TTM) 94.5
Enterprise Value 440578241
Price to Sales(TTM) 94.5
Enterprise Value to Revenue 54.24
Enterprise Value to EBITDA -6.86
Shares Outstanding 20369000
Shares Floating 15702041
Shares Outstanding 20369000
Shares Floating 15702041
Percent Insiders 0.16
Percent Institutions 116.76

Analyst Ratings

Rating 4.42
Target Price 97.67
Buy 3
Strong Buy 8
Buy 3
Strong Buy 8
Hold -
Sell -
Strong Sell 1
Strong Sell 1

ai summary icon Upturn AI SWOT

Praxis Precision Medicines Inc

Company Overview

overview logo History and Background

Praxis Precision Medicines, Inc. is a biopharmaceutical company focused on developing therapies for central nervous system (CNS) disorders. Founded in 2015, Praxis has advanced multiple programs into clinical development.

business area logo Core Business Areas

  • Neurology: Development of therapies for epilepsy, including focal onset seizures and other rare epilepsies.
  • Neuropsychiatry: Research and development of treatments for mood and anxiety disorders.

leadership logo Leadership and Structure

The leadership team includes executives with experience in drug development and commercialization. The company operates with a structure focused on research and clinical development.

Top Products and Market Share

overview logo Key Offerings

  • PRAX-19: An investigational antisense oligonucleotide targeting a specific subunit of the GABA-A receptor. Currently in clinical trials. Competitors: Multiple pharmaceutical companies developing antiseizure medications.
  • PRAX-562: An investigational molecule targeting the neuronal hyperxcitability, or hyperexcitability, that causes neurological disorder symptoms. Currently in clinical trials. Competitors: Other pharmaceutical companies developing neurological disorder medications

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry focused on CNS disorders is a large and competitive market with significant unmet medical needs.

Positioning

Praxis is positioned as a precision medicines company, targeting specific genetic and molecular drivers of CNS disorders. This personalized approach aims to improve treatment efficacy.

Total Addressable Market (TAM)

The TAM for CNS disorders is substantial. Praxis is positioned to address specific segments of this market with its targeted therapies.

Upturn SWOT Analysis

Strengths

  • Precision medicine approach
  • Experienced management team
  • Diverse pipeline of drug candidates
  • Focus on unmet medical needs

Weaknesses

  • Clinical trial risks
  • Limited commercialized products
  • Reliance on partnerships and funding
  • High R&D expenses

Opportunities

  • Expansion of pipeline into new CNS disorders
  • Partnerships with larger pharmaceutical companies
  • Successful clinical trial outcomes
  • Regulatory approvals and commercialization of products

Threats

  • Clinical trial failures
  • Competition from established pharmaceutical companies
  • Changes in regulatory landscape
  • Patent expirations

Competitors and Market Share

competitor logo Key Competitors

  • EPIX
  • AZN
  • GSK

Competitive Landscape

Praxis is a smaller player compared to established pharmaceutical giants. Its competitive advantage lies in its precision medicine approach and focus on specific patient populations.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Praxis' growth is measured by advancements in clinical trials and expansion of the pipeline.

Future Projections: Future growth projections rely on successful clinical trial results and regulatory approvals. Analyst estimates are based on potential product sales.

Recent Initiatives: Recent initiatives include advancing PRAX-19 and PRAX-562 through clinical development, and focusing on strategic pipeline expansion.

Summary

Praxis Precision Medicines is a clinical-stage biopharmaceutical company with a focus on CNS disorders. While the company is still in the development phase and faces significant clinical trial risks, it has a compelling precision medicine approach and an experienced team. Future success hinges on positive clinical trial outcomes and regulatory approvals. The company needs to maintain its cash runway and manage its R&D expenses effectively.

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Sources and Disclaimers

Data Sources:

  • Company Website
  • SEC Filings
  • Analyst Reports
  • Market Research Reports

Disclaimers:

This analysis is for informational purposes only and should not be considered financial advice. The data provided is based on publicly available information, and its accuracy cannot be guaranteed.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Praxis Precision Medicines Inc

Exchange NASDAQ
Headquaters Boston, MA, United States
IPO Launch date 2020-10-16
President, CEO & Director Mr. Marcio Silva De'Souza M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 116
Full time employees 116

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance. The company's platforms include cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies; and solidus to discover and develop antisense oligonucleotide. It also develops Ulixacaltamide, a small molecule inhibitor of T-type calcium channels that is in Phase 3 clinical trial for the treatment of essential tremor; Vormatrigine, a small molecule targeting the hyperexcitable state of sodium-channels in the brain to treat focal onset epilepsy; Relutrigine for the treatment of developmental and epileptic encephalopathies; PRAX-020 to treat KCNT1; and PRAX-050. In addition, the company develops Elsunersen, a clinical-stage ASO designed to regulate NaV1.2 expression for the treatment of SCN2A-DEE; PRAX-080 that targets PCDH19-related developmental epilepsy; PRAX-090 for targeting SYNGAP1 loss-of-function; and PRAX-100 that targets SCN2A LoF mutations. It has a license agreement with RogCon Inc.; and research collaboration and license agreement with Ionis Pharmaceuticals, Inc. Praxis Precision Medicines, Inc. was incorporated in 2015 and is based in Boston, Massachusetts.