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Replimune Group Inc(REPL)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for REPL
11/02/2026: REPL (1-star) is currently NOT-A-BUY. Pass it for now.
Replimune Group Inc is a clinical-stage biotechnology firm dedicated to developing novel oncolytic immunotherapies for solid tumors. Its primary value proposition lies in its proprietary Immulytic platform, which aims to trigger systemic immune responses against cancer. While the company has made progress in advancing candidates like RP1 through clinical stages, it remains pre-revenue and faces high execution and financial risks common in the biotech sector. Investors should monitor the company's clinical trial results and capital management, as its valuation is heavily dependent on data outcomes. This stock is best suited for speculative, risk-tolerant investors looking for long-term growth potential in the immuno-oncology space.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high-risk, high-reward potential based on its pipeline but lacks the revenue growth typical of mature growth investments. |
| Momentum investor | Strong fit while signal remains positive | Stock price is highly sensitive to binary clinical data events, making it a potential candidate during positive news cycles. |
| Value investor | Weak fit | As a pre-revenue biotech, there are no traditional earnings or cash flow metrics to support a value-based valuation. |
| Dividend investor | Weak fit | The company does not pay dividends and prioritizes capital reinvestment in R&D. |
| Low-risk investor | Weak fit | The high volatility and binary nature of clinical outcomes present significant risks unsuitable for risk-averse portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical trial results can cause substantial, sudden swings in stock price. |
| Valuation risk | High | Valuation is speculative and dependent on future success rather than current financial performance. |
| Competition risk (Immuno-oncology) | High | The company faces intense pressure from large-cap biopharma firms with superior financial resources. |
| Business quality | Medium | While the technology is scientifically grounded, the firm lacks a diversified product or commercial revenue base. |
| Dividend income | Low / none | No income is generated for shareholders. |
| Execution risk | High | The complexity of developing viral therapies requires flawless clinical trial execution. |
Price Behavior
Strong Uptrend
The stock has maintained a strong upward price trend across the last three quarters.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit -70.49% | Avg. Invested days 42 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  3.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/02/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.85B USD | Price to earnings Ratio - | 1Y Target Price 23.33 |
Price to earnings Ratio - | 1Y Target Price 23.33 | ||
Volume (30-day avg) 2.6M shares | Beta 0.93 | 52 Weeks Range 1.50 - 19.68 | Updated Date 11/02/2026 |
52 Weeks Range 1.50 - 19.68 | Updated Date 11/02/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -3.08 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Clinical Development | Research and development of proprietary oncolytic immunotherapies like RP1, RP2, and RP3. | The company currently spends money to develop products and does not yet generate revenue from sales. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 1.49B | Price to Sales(TTM) - |
Enterprise Value 1.49B | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.24 | Shares Outstanding 94.80M | Shares Floating 68.23M |
Shares Outstanding 94.80M | Shares Floating 68.23M | ||
Percent Insiders 1.64 | Percent Institutions 105.25 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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