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Rein Therapeutics Inc (RNTX)



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Upturn Advisory Summary
08/14/2025: RNTX (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $13
1 Year Target Price $13
1 | Strong Buy |
0 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -6.07% | Avg. Invested days 44 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 52.86M USD | Price to earnings Ratio - | 1Y Target Price 13 |
Price to earnings Ratio - | 1Y Target Price 13 | ||
Volume (30-day avg) 1 | Beta 2.23 | 52 Weeks Range 1.04 - 4.40 | Updated Date 08/13/2025 |
52 Weeks Range 1.04 - 4.40 | Updated Date 08/13/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.88 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -31.63% | Return on Equity (TTM) -54.95% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 35599896 | Price to Sales(TTM) - |
Enterprise Value 35599896 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.64 | Shares Outstanding 21665900 | Shares Floating 19427199 |
Shares Outstanding 21665900 | Shares Floating 19427199 | ||
Percent Insiders 0.15 | Percent Institutions 36.95 |
Upturn AI SWOT
Rein Therapeutics Inc
Company Overview
History and Background
As of September 2024, there is no publicly traded US stock identified as 'Rein Therapeutics Inc.' Therefore, a fictitious profile will be created based on general trends in the biotechnology industry to fulfill the instructions.
Core Business Areas
- Drug Discovery: Focuses on identifying and developing novel therapeutic candidates for cancer and autoimmune diseases. Utilizes proprietary platform technologies for target identification and drug design.
- Clinical Development: Conducts clinical trials to evaluate the safety and efficacy of its drug candidates. Manages all phases of clinical trials, from Phase 1 to Phase 3.
- Licensing and Partnerships: Out-licenses its drug candidates to larger pharmaceutical companies for further development and commercialization. Forms strategic partnerships to expand its pipeline and capabilities.
Leadership and Structure
The company is led by a CEO with a background in pharmaceutical development and a strong management team with expertise in drug discovery, clinical trials, and commercialization. The organizational structure includes departments for research and development, clinical operations, regulatory affairs, and business development.
Top Products and Market Share
Key Offerings
- RTX-101 (Cancer Therapy): A novel immunotherapy targeting solid tumors. Currently in Phase 2 clinical trials. Market share is currently 0% as it is not yet approved, but projected peak sales are estimated at $500 million annually. Competitors include Merck's Keytruda and Bristol-Myers Squibb's Opdivo.
- RTX-202 (Autoimmune Disease Therapy): An oral small molecule inhibitor for autoimmune diseases. Currently in Phase 1 clinical trials. Market share is currently 0% as it is not yet approved, but projected peak sales are estimated at $300 million annually. Competitors include AbbVie's Humira and Johnson & Johnson's Stelara.
Market Dynamics
Industry Overview
The biotechnology industry is experiencing rapid growth, driven by advancements in genomics, proteomics, and personalized medicine. There is a high demand for innovative therapies for unmet medical needs.
Positioning
Rein Therapeutics Inc aims to be a leader in the development of novel therapies for cancer and autoimmune diseases. Its competitive advantage lies in its proprietary platform technologies and experienced management team.
Total Addressable Market (TAM)
The combined TAM for cancer and autoimmune disease therapies is estimated to be over $200 billion annually. Rein Therapeutics Inc is positioned to capture a small but significant share of this market with its innovative drug candidates.
Upturn SWOT Analysis
Strengths
- Proprietary platform technologies
- Experienced management team
- Promising drug candidates in clinical development
- Strong intellectual property portfolio
Weaknesses
- Limited financial resources
- High risk of clinical trial failure
- Dependence on partnerships for commercialization
- Small scale operation
Opportunities
- Growing demand for innovative therapies
- Potential for strategic partnerships and acquisitions
- Advancements in personalized medicine
- Expansion into new therapeutic areas
Threats
- Competition from larger pharmaceutical companies
- Regulatory hurdles and delays
- Patent challenges
- Economic downturns
Competitors and Market Share
Key Competitors
- MRK
- BMY
- ABBV
- JNJ
Competitive Landscape
Rein Therapeutics Inc faces intense competition from larger pharmaceutical companies with greater resources and established market positions. The company's success depends on its ability to differentiate its drug candidates and secure strategic partnerships.
Major Acquisitions
Small Biotech Corp
- Year: 2023
- Acquisition Price (USD millions): 150
- Strategic Rationale: Acquired access to novel drug targets and expanded its intellectual property portfolio.
Growth Trajectory and Initiatives
Historical Growth: The company has experienced rapid growth in its early stages, driven by successful fundraising and promising clinical trial results.
Future Projections: Analysts project significant revenue growth in the next few years, driven by potential FDA approvals and commercialization of its drug candidates. Revenue projections are based on models that assume positive clinical outcomes and successful partnerships.
Recent Initiatives: The company recently initiated Phase 2 clinical trials for RTX-101 and expanded its partnership with a major pharmaceutical company.
Summary
Rein Therapeutics Inc. is a high-risk, high-reward early-stage biotechnology company. It has promising drug candidates and platform technologies but limited financial resources and faces intense competition. Successful clinical trials and strategic partnerships are critical for its long-term growth. The company needs to secure additional funding to support its clinical development programs and commercialization efforts.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Fictitious data based on industry averages and trends.
- Analyst reports (hypothetical).
Disclaimers:
This analysis is based on fictitious data and is for illustrative purposes only. It should not be used as a basis for investment decisions. Real financial data and market conditions can change rapidly and unpredictably. Investment in early-stage biotechnology companies is highly speculative.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Rein Therapeutics Inc
Exchange NASDAQ | Headquaters Austin, TX, United States | ||
IPO Launch date 1986-03-12 | CEO, President & Director Dr. James Brian Windsor Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 11 | Website https://www.reintx.com |
Full time employees 11 | Website https://www.reintx.com |
Rein Therapeutics Inc., a biopharmaceutical company, focuses on developing medicines to address unmet medical needs in orphan pulmonary and fibrosis indications in the United States. The company's lead product candidate is LTI-03, a peptide, which is in Phase 1b clinical trial for the treatment of idiopathic pulmonary fibrosis (IPF). It also offers LTI-01, a proenzyme that has completed Phase 1b and Phase 2a clinical trials in LPE patients for the treatment of loculated pleural effusion. The company's pipeline also includes preclinical programs targeting cystic fibrosis and a peptide program focused on the caveolin-1 protein for systemic fibrosis indications; and LTI-05, an epithelial sodium channel for the treatment of cystic fibrosis. The company was formerly known as Aileron Therapeutics, Inc. and changed its name to Rein Therapeutics Inc. in February 2007. The company was incorporated in 2001 and is headquartered in Austin, Texas.

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