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Schrodinger Inc (SDGR)

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Upturn Advisory Summary
12/05/2025: SDGR (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $27.22
1 Year Target Price $27.22
| 6 | Strong Buy |
| 0 | Buy |
| 2 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -53.65% | Avg. Invested days 29 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.30B USD | Price to earnings Ratio - | 1Y Target Price 27.22 |
Price to earnings Ratio - | 1Y Target Price 27.22 | ||
Volume (30-day avg) 8 | Beta 1.57 | 52 Weeks Range 15.99 - 28.47 | Updated Date 12/7/2025 |
52 Weeks Range 15.99 - 28.47 | Updated Date 12/7/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.4 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -68.49% | Operating Margin (TTM) -84.58% |
Management Effectiveness
Return on Assets (TTM) -16.1% | Return on Equity (TTM) -45.67% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 1019646360 | Price to Sales(TTM) 5.06 |
Enterprise Value 1019646360 | Price to Sales(TTM) 5.06 | ||
Enterprise Value to Revenue 3.97 | Enterprise Value to EBITDA -10.82 | Shares Outstanding 64500510 | Shares Floating 57612428 |
Shares Outstanding 64500510 | Shares Floating 57612428 | ||
Percent Insiders 2.58 | Percent Institutions 109.38 |
Upturn AI SWOT
Schrodinger Inc

Company Overview
History and Background
Schru00f6dinger, Inc. was founded in 1990 by Robert Berndits, Roger Newton, and William Vernier. The company initially focused on developing computational chemistry software. Over the years, it has evolved to become a leading provider of advanced materials science and pharmaceutical research software solutions. Key milestones include the development of its physics-based modeling platform and its expansion into drug discovery services.
Core Business Areas
- Software Solutions: Schru00f6dinger develops and licenses advanced computational software used in drug discovery, materials science, and related R&D fields. Their platform enables scientists to design and optimize molecules and materials through simulation and prediction.
- Discovery Services: The company offers integrated drug discovery services, leveraging its software platform and scientific expertise to help pharmaceutical and biotechnology companies advance their R&D pipelines.
Leadership and Structure
Schru00f6dinger is led by its co-founder and CEO, Dr. Ramy Farid. The company operates with a scientific and engineering-driven organizational structure, emphasizing innovation and collaboration between its software development and drug discovery teams.
Top Products and Market Share
Key Offerings
- Schru00f6dinger Platform (FEP+, Maestro, LiveDesign): This is Schru00f6dinger's flagship integrated software suite. It encompasses tools for molecular modeling, simulation (including Free Energy Perturbation - FEP+), drug design, and data management. Its primary competitors include Dassault Systu00e8mes (BIOVIA), OpenEye Scientific, and various in-house computational chemistry departments. Market share data for specific software products is not publicly disclosed but is estimated to be significant within its niche.
- Drug Discovery Programs: Schru00f6dinger engages in collaborative and internal drug discovery programs. While not a distinct product in the same way as software, these services represent a growing revenue stream. Competitors in this space include contract research organizations (CROs) and other biotech companies with internal discovery capabilities.
Market Dynamics
Industry Overview
Schru00f6dinger operates within the highly specialized markets of computational chemistry software, drug discovery software, and R&D services for the pharmaceutical and materials science industries. These sectors are characterized by rapid technological advancements, a strong demand for efficiency in R&D, and significant investment in innovation.
Positioning
Schru00f6dinger is positioned as a leader in physics-based computational chemistry software, particularly for drug discovery. Its key competitive advantage lies in its proprietary simulation technologies, especially FEP+, which are renowned for their accuracy in predicting binding affinities and properties. The integration of its software with discovery services further strengthens its offering.
Total Addressable Market (TAM)
The TAM for computational drug discovery and materials science software and services is substantial and growing, driven by the increasing complexity of drug targets and the need for faster, more efficient R&D. While exact TAM figures vary by analysis, it is estimated to be in the tens of billions of dollars globally. Schru00f6dinger's current market share represents a significant portion of the high-end computational software segment and a growing presence in the R&D services market.
Upturn SWOT Analysis
Strengths
- Proprietary and highly regarded simulation technology (FEP+).
- Integrated software and discovery services offering.
- Strong scientific and technical talent pool.
- Established relationships with major pharmaceutical and biotechnology companies.
- Continuous innovation and development in its core platform.
Weaknesses
- Dependence on a relatively niche market.
- High R&D costs associated with maintaining technological edge.
- Long sales cycles for enterprise software solutions.
- Limited brand recognition outside of the scientific community.
Opportunities
- Expansion into new therapeutic areas and disease targets.
- Growth in the broader AI/ML applications for drug discovery.
- Further penetration into the materials science market.
- Strategic partnerships and collaborations with larger pharma.
- Geographic expansion into emerging markets.
Threats
- Competition from established software providers and emerging AI-driven platforms.
- Changes in pharmaceutical R&D spending and priorities.
- Regulatory hurdles and the pace of drug development failures.
- Cybersecurity risks for sensitive intellectual property.
- Potential for commoditization of certain computational tasks.
Competitors and Market Share
Key Competitors
- Dassault Systu00e8mes (BIOVIA) (DAST)
- OpenEye Scientific (Private)
- Certara, Inc. (CERT)
Competitive Landscape
Schru00f6dinger's advantage lies in its deep scientific expertise and highly sophisticated, physics-based simulation tools, particularly FEP+. While Dassault Systu00e8mes offers a broader suite of R&D software, and Certara focuses on preclinical and clinical R&D services, Schru00f6dinger's niche in molecular simulation and design is a strong differentiator. The company's integrated approach to software and services provides a competitive edge.
Growth Trajectory and Initiatives
Historical Growth: Schru00f6dinger has exhibited strong historical growth in revenue, largely attributed to the increasing demand for its advanced computational software and the expansion of its drug discovery services. The company has consistently invested in its technology and scientific capabilities to drive this growth.
Future Projections: Analyst projections for Schru00f6dinger's future growth are generally positive, driven by the expanding TAM for computational drug discovery and the company's strong technological foundation. Growth is expected to be fueled by continued software license sales, growth in discovery services, and potential new therapeutic area expansions.
Recent Initiatives: Recent initiatives likely include ongoing development of its core platform, expansion of its AI/ML capabilities for drug discovery, strategic collaborations, and the advancement of its internal drug discovery pipeline.
Summary
Schru00f6dinger Inc. is a strong player in the computational chemistry and drug discovery software market, with a differentiated technology and an integrated service offering. Its core strength lies in its advanced simulation platform, which is crucial for pharmaceutical R&D. The company needs to remain vigilant against emerging AI-driven competitors and ensure continued innovation to maintain its market position. Future growth is expected to be driven by expanding its software adoption and growing its R&D services.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Schru00f6dinger Inc. SEC Filings (10-K, 10-Q)
- Company Investor Relations
- Industry Analysis Reports
- Financial News Outlets
Disclaimers:
This information is compiled from publicly available sources and is for informational purposes only. It does not constitute financial advice. Investors should conduct their own due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Schrodinger Inc
Exchange NASDAQ | Headquaters New York, NY, United States | ||
IPO Launch date 2020-02-06 | CEO, President & Director Dr. Ramy Farid Ph.D. | ||
Sector Healthcare | Industry Health Information Services | Full time employees 891 | Website https://www.schrodinger.com |
Full time employees 891 | Website https://www.schrodinger.com | ||
Schrödinger, Inc., together with its subsidiaries, develops physics-based computational platform that enables discovery of novel molecules for drug development and materials applications. The company operates in two segments, Software and Drug Discovery. The Software segment sells its software to transform molecular discovery for life sciences and materials science industries. The Drug Discovery segment focuses on building a portfolio of preclinical and clinical programs, internally and through collaborations. It has a research collaboration and license agreement with Novartis Pharma AG to advance multiple development candidates. Schrödinger, Inc. was incorporated in 1990 and is based in New York, New York.

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