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SHPH
Upturn stock rating

Shuttle Pharmaceuticals Inc (SHPH)

Upturn stock rating
$3.09
Last Close (24-hour delay)
upturn advisory
PASS
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  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
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  • Pass (Skip investing)
Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

10/23/2025: SHPH (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -44.09%
Avg. Invested days 17
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/23/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 37.68M USD
Price to earnings Ratio -
1Y Target Price -
Price to earnings Ratio -
1Y Target Price -
Volume (30-day avg) -
Beta 0.41
52 Weeks Range 3.00 - 107.40
Updated Date 06/29/2025
52 Weeks Range 3.00 - 107.40
Updated Date 06/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -69.25

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -115.05%
Return on Equity (TTM) -346.2%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 34845478
Price to Sales(TTM) -
Enterprise Value 34845478
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.67
Shares Outstanding 10984300
Shares Floating 411243
Shares Outstanding 10984300
Shares Floating 411243
Percent Insiders 5.82
Percent Institutions 0.94

ai summary icon Upturn AI SWOT

Shuttle Pharmaceuticals Inc

stock logo

Company Overview

overview logo History and Background

Shuttle Pharmaceuticals, Inc. is a pharmaceutical company focused on improving the outcomes of cancer patients treated with radiation therapy. Founded with a focus on developing proprietary formulations to enhance cancer treatment effectiveness and reduce side effects.

business area logo Core Business Areas

  • Drug Development: Focuses on the development of novel therapeutic candidates designed to improve cancer treatment outcomes by protecting normal tissue during radiation therapy.
  • Clinical Trials: Conducting clinical trials to evaluate the safety and efficacy of its drug candidates.
  • Partnerships: Forming strategic alliances with research institutions and pharmaceutical companies.

leadership logo Leadership and Structure

The leadership team comprises experienced professionals in drug development, clinical research, and business management. Organizational structure includes scientific advisory board and executive management.

Top Products and Market Share

overview logo Key Offerings

  • Ropidoxuridine: A lead drug candidate designed to protect normal tissue during cancer radiation therapy. Market share is currently 0% as it is still in development. Competitors include companies developing similar radioprotective agents or improving radiation delivery techniques.
  • SP-1-164: Another drug candidate in preclinical development, with similar intended use. Market share 0%. Competitors include companies developing similar radioprotective agents or improving radiation delivery techniques.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry, particularly in oncology and radioprotection, is highly competitive and regulated, with significant research and development investments and strict regulatory approval processes.

Positioning

Shuttle Pharmaceuticals is positioned as a company developing novel radioprotective agents. Its competitive advantage lies in its proprietary formulations and targeted approach to reducing radiation-induced side effects.

Total Addressable Market (TAM)

The total addressable market for radioprotective agents is estimated to be in the billions, growing with increasing cancer incidence and radiation therapy usage. Shuttle Pharmaceuticals is positioned to capture a segment of this market with successful drug development and commercialization.

Upturn SWOT Analysis

Strengths

  • Novel drug candidates with a targeted mechanism of action
  • Experienced leadership team
  • Focus on unmet medical need in radioprotection
  • Strong IP portfolio

Weaknesses

  • Early-stage development with significant regulatory and clinical risks
  • Limited financial resources
  • Dependence on successful clinical trial outcomes
  • No current revenue streams

Opportunities

  • Potential for breakthrough therapy designation
  • Partnerships with larger pharmaceutical companies
  • Expansion into new cancer indications
  • Government grants and funding opportunities

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from established pharmaceutical companies
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • POLA
  • GTBP
  • JANX

Competitive Landscape

Shuttle Pharmaceuticals competes with other pharmaceutical companies developing radiation therapy drugs and companies offering radiation therapy techniques. The competitive landscape is characterized by innovation, regulatory requirements, and a focus on improved patient outcomes.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is characterized by the development of drugs, rather than revenue generation.

Future Projections: Future growth is contingent on successful clinical trial outcomes and regulatory approvals.

Recent Initiatives: Recent initiatives include advancing the clinical development of Ropidoxuridine and SP-1-164, and seeking strategic partnerships.

Summary

Shuttle Pharmaceuticals is a development-stage pharmaceutical company with promising drug candidates for radioprotection in cancer therapy. The company's success hinges on positive clinical trial results and regulatory approvals. Its strengths are in novel drug development, while weaknesses lie in its early-stage status and limited resources. The company should capitalize on partnership opportunities and mitigate clinical and regulatory risks.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Third-party market research reports

Disclaimers:

This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be made based on thorough research and consultation with a qualified financial advisor.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Shuttle Pharmaceuticals Inc

Exchange NASDAQ
Headquaters Gaithersburg, MD, United States
IPO Launch date 2022-08-31
CEO -
Sector Healthcare
Industry Drug Manufacturers - Specialty & Generic
Full time employees 9
Full time employees 9

Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. The company is developing Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas; and SP-2-225, a pre-clinical class IIb product candidate that effects on the regulation of the immune system. It is also developing SP-1-303, a pre-clinical selective Class I HDAC for use in the treatment of ER positive breast cancers; and SP-1-161, a HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway. The company was founded in 2012 and is headquartered in Gaithersburg, Maryland.