SHPH
SHPH 1-star rating from Upturn Advisory

Shuttle Pharmaceuticals Inc (SHPH)

Shuttle Pharmaceuticals Inc (SHPH) 1-star rating from Upturn Advisory
$1.87
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Upturn Advisory Summary

12/26/2025: SHPH (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -44.09%
Avg. Invested days 17
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 12/26/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 37.68M USD
Price to earnings Ratio -
1Y Target Price -
Price to earnings Ratio -
1Y Target Price -
Volume (30-day avg) -
Beta 0.41
52 Weeks Range 3.00 - 107.40
Updated Date 06/29/2025
52 Weeks Range 3.00 - 107.40
Updated Date 06/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -69.25

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -115.05%
Return on Equity (TTM) -346.2%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 34845478
Price to Sales(TTM) -
Enterprise Value 34845478
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.67
Shares Outstanding 10984300
Shares Floating 411243
Shares Outstanding 10984300
Shares Floating 411243
Percent Insiders 5.82
Percent Institutions 0.94

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI SWOT

Shuttle Pharmaceuticals Inc

Shuttle Pharmaceuticals Inc(SHPH) company logo displayed in Upturn AI summary

Company Overview

Company history and background logo History and Background

Shuttle Pharmaceuticals Inc. was founded in 1994 by Dr. Joseph Sinkule. The company's primary focus has been on developing novel cancer therapies, particularly in the area of radiation sensitizers. Significant milestones include the development of radiation-enhancing drugs, early-stage clinical trials, and securing intellectual property. The company has evolved by adapting its research pipeline and seeking strategic partnerships to advance its drug candidates.

Company business area logo Core Business Areas

  • Oncology Drug Development: Shuttle Pharmaceuticals Inc. is dedicated to the discovery, development, and commercialization of innovative therapies for the treatment of cancer. Their research primarily centers on radiation sensitizers, compounds designed to make cancer cells more susceptible to radiation therapy, thereby improving treatment outcomes and potentially reducing the required radiation dose.

leadership logo Leadership and Structure

Information regarding the specific current leadership team and detailed organizational structure for Shuttle Pharmaceuticals Inc. is not readily available through public financial disclosures or typical company profiles. As a smaller, publicly traded entity, detailed organizational charts and executive biographies may be limited in public access.

Top Products and Market Share

Product Key Offerings logo Key Offerings

  • Product Name 1: Radiation Sensitizer Drugs (e.g., PH-02, PH-03, PH-04, PH-05). These are investigational drugs designed to enhance the efficacy of radiation therapy in treating various cancers. Specific market share data or revenue figures are not publicly disclosed as these are still in development and have not achieved commercialization. Key competitors in the broader oncology drug market include large pharmaceutical companies with extensive oncology portfolios.

Market Dynamics

industry overview logo Industry Overview

The oncology drug development industry is a dynamic and highly competitive sector characterized by significant R&D investment, stringent regulatory processes, and a constant drive for innovation. The market for cancer therapies is substantial and growing, fueled by an aging population, increased cancer incidence, and advancements in understanding disease biology. Radiation oncology is a significant sub-segment within this market.

Positioning

Shuttle Pharmaceuticals Inc. positions itself as a developer of novel, targeted therapies focused on improving the effectiveness of existing cancer treatments, particularly radiation therapy. Their competitive advantage lies in their proprietary technology and intellectual property related to radiation sensitizers. However, as a smaller company, they face challenges in competing with larger, well-established pharmaceutical companies with greater resources for development and commercialization.

Total Addressable Market (TAM)

The total addressable market for cancer therapies is in the hundreds of billions of dollars globally and continues to grow. The specific TAM for radiation sensitizers is a subset of this larger market and is expected to expand with advancements in radiation oncology and the development of effective sensitizing agents. Shuttle Pharmaceuticals Inc. aims to capture a portion of this market with its innovative drug candidates, but its current market position is nascent as its products are still in development.

Upturn SWOT Analysis

Strengths

  • Proprietary technology in radiation sensitizers
  • Patented drug candidates
  • Focus on a specific, high-need area of cancer treatment
  • Experienced scientific team (historically)

Weaknesses

  • Limited financial resources compared to larger competitors
  • Reliance on external funding for R&D and clinical trials
  • Long development timelines typical of pharmaceutical products
  • Lack of commercialized products

Opportunities

  • Growing demand for more effective cancer treatments
  • Potential for strategic partnerships and collaborations
  • Advancements in radiation therapy techniques
  • Acquisition by larger pharmaceutical companies

Threats

  • High failure rate in drug development
  • Intense competition from established and emerging biotech companies
  • Regulatory hurdles and approval delays
  • Patent expirations and generic competition for related therapies
  • Changes in healthcare policy and reimbursement

Competitors and Market Share

Key competitor logo Key Competitors

  • N/A (As Shuttle Pharmaceuticals Inc. is a small, developmental stage company with no commercialized products, defining 'key competitors' in terms of market share is not feasible. The competitive landscape is broad, encompassing many oncology drug developers.)

Competitive Landscape

Shuttle Pharmaceuticals Inc.'s competitive landscape is characterized by numerous pharmaceutical and biotechnology companies, many of which are significantly larger and better capitalized, actively developing therapies for various cancers. Their advantage lies in their specialized focus on radiation sensitizers, while their disadvantage stems from their limited resources and the high risk associated with drug development.

Growth Trajectory and Initiatives

Historical Growth: Historical growth for Shuttle Pharmaceuticals Inc. has primarily been tied to its progress in drug discovery and development, and its ability to raise capital to fund these endeavors. There has been no revenue-based growth as the company does not have commercialized products.

Future Projections: Future projections for Shuttle Pharmaceuticals Inc. are highly speculative and depend entirely on the successful clinical development and regulatory approval of its drug candidates. Analyst coverage and projections are not widely available for companies at this stage. Success in clinical trials would be the primary driver of future valuation and potential growth.

Recent Initiatives: Recent initiatives would likely involve continued preclinical and clinical research on their radiation sensitizer compounds, efforts to secure funding for ongoing trials, and potential engagement with strategic partners for further development or commercialization.

Summary

Shuttle Pharmaceuticals Inc. is a developmental stage biotechnology company focused on creating novel cancer therapies, specifically radiation sensitizers. While possessing proprietary technology and a clear, unmet medical need focus, its strengths are overshadowed by its limited financial resources and the inherent risks of drug development. The company needs to secure substantial funding and achieve significant clinical trial success to overcome competitive pressures and move towards commercialization.

Similar Stocks

Sources and Disclaimers

Data Sources:

  • SEC Filings (e.g., 10-K, 10-Q)
  • Company Press Releases (if available)
  • Financial Data Aggregators (limited for small-cap developmental companies)

Disclaimers:

The information provided is based on publicly available data and is intended for informational purposes only. Shuttle Pharmaceuticals Inc. is a developmental stage company, and investing in such companies carries significant risks. Financial data and company status are subject to change. This analysis does not constitute investment advice. All numerical data is presented for potential graphical representation. Market share and competitor data for developmental stage companies are highly speculative or non-existent in a commercial sense.

Information icon for Upturn AI Summarization accuracy disclaimer AI Summarization is directionally correct and might not be accurate.

Information icon for Upturn AI Summarization data freshness disclaimer Summarized information shown could be a few years old and not current.

Information icon warning about Upturn AI Fundamental Rating based on potentially old data Fundamental Rating based on AI could be based on old data.

Information icon warning about potential inaccuracies or hallucinations in Upturn AI-generated summaries AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Shuttle Pharmaceuticals Inc

Exchange NASDAQ
Headquaters Gaithersburg, MD, United States
IPO Launch date 2022-08-31
CEO -
Sector Healthcare
Industry Drug Manufacturers - Specialty & Generic
Full time employees 9
Full time employees 9

Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. The company is developing Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas; and SP-2-225, a pre-clinical class IIb product candidate that effects on the regulation of the immune system. It is also developing SP-1-303, a pre-clinical selective Class I HDAC for use in the treatment of ER positive breast cancers; and SP-1-161, a HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway. The company was founded in 2012 and is headquartered in Gaithersburg, Maryland.