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SHPH
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Shuttle Pharmaceuticals Inc (SHPH)

Upturn stock ratingUpturn stock rating
$3.58
Last Close (24-hour delay)
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PASS
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  • SELL Advisory (Loss)​
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Upturn Advisory Summary

09/16/2025: SHPH (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -32.54%
Avg. Invested days 16
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/16/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 37.68M USD
Price to earnings Ratio -
1Y Target Price -
Price to earnings Ratio -
1Y Target Price -
Volume (30-day avg) -
Beta 0.41
52 Weeks Range 3.00 - 107.40
Updated Date 06/29/2025
52 Weeks Range 3.00 - 107.40
Updated Date 06/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -69.25

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -115.05%
Return on Equity (TTM) -346.2%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 34845478
Price to Sales(TTM) -
Enterprise Value 34845478
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.67
Shares Outstanding 10984300
Shares Floating 411243
Shares Outstanding 10984300
Shares Floating 411243
Percent Insiders 5.82
Percent Institutions 0.94

ai summary icon Upturn AI SWOT

Shuttle Pharmaceuticals Inc

stock logo

Company Overview

overview logo History and Background

Shuttle Pharmaceuticals, Inc. focuses on developing novel therapies to improve the outcomes of cancer patients undergoing radiation therapy. Founded to address unmet needs in cancer treatment, the company is relatively young and has been focusing on early-stage drug development and clinical trials.

business area logo Core Business Areas

  • Radiation Sensitizers: Development of drugs that enhance the effectiveness of radiation therapy, making cancer cells more susceptible to radiation damage.
  • Drug Development: Researching and developing novel therapeutic agents designed to protect normal tissue and minimize the toxicity to that normal tissue during radiation treatment of cancer.
  • Clinical Trials: Conducting clinical trials to evaluate the safety and efficacy of its lead drug candidates.

leadership logo Leadership and Structure

The leadership team consists of experienced pharmaceutical executives and scientists. The organizational structure is typical of a small biotech company, with focus on research and development.

Top Products and Market Share

overview logo Key Offerings

  • Ropidoxuridine: A lead drug candidate being developed as a radiation sensitizer for various cancers. Market share is currently zero as the drug is still in clinical trials. The market potential depends on the drug's successful completion of clinical trials and regulatory approvals. Competitors include companies developing similar radiation sensitizers and improved radiation therapy techniques.

Market Dynamics

industry overview logo Industry Overview

The oncology market is large and growing, driven by increasing cancer incidence and advancements in cancer treatment. There is a significant need for therapies that improve the effectiveness and reduce the side effects of radiation therapy.

Positioning

Shuttle Pharmaceuticals is positioned as a developer of novel radiation sensitizers. Its competitive advantage lies in its specific drug candidates and their potential to enhance radiation therapy outcomes with reduced toxicity. The company is focused on addressing unmet clinical needs in specific cancer types.

Total Addressable Market (TAM)

The TAM for radiation sensitizers is estimated to be in the billions of dollars, depending on the success of clinical trials and regulatory approvals. Shuttle Pharmaceuticals is positioned to capture a portion of this market if its lead drug candidate is successfully developed and commercialized.

Upturn SWOT Analysis

Strengths

  • Novel drug candidates with the potential to improve radiation therapy outcomes
  • Experienced leadership team
  • Focus on addressing unmet clinical needs in oncology

Weaknesses

  • Early-stage drug development company with no marketed products
  • High dependence on successful clinical trial outcomes
  • Limited financial resources

Opportunities

  • Potential to partner with larger pharmaceutical companies for drug development and commercialization
  • Expansion into new cancer types and treatment modalities
  • Increasing demand for improved cancer therapies with reduced side effects

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from other companies developing similar therapies
  • Changes in the standard of care for cancer treatment

Competitors and Market Share

competitor logo Key Competitors

  • MRTX
  • GSK
  • AZN

Competitive Landscape

Shuttle Pharmaceuticals faces competition from established pharmaceutical companies with larger resources and more advanced drug development programs. Its advantage lies in its focus on novel radiation sensitizers and addressing unmet clinical needs.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is reflected in the progress of drug development programs and fundraising efforts. As of the last update, the company is in early clinical trials.

Future Projections: Future growth depends on the successful completion of clinical trials and regulatory approvals. Analyst estimates, if available, would depend on these factors.

Recent Initiatives: Recent initiatives include initiating and advancing clinical trials for its lead drug candidate.

Summary

Shuttle Pharmaceuticals is an early-stage pharmaceutical company focused on developing radiation sensitizers to improve cancer therapy outcomes. The company's success hinges on the positive results of its clinical trials and regulatory approvals. They face high risks and competition, but could be rewarded if their drug shows promise. Key areas of focus are fundraising, trial execution, and potential partnerships.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Industry reports
  • ClinicalTrials.gov

Disclaimers:

This analysis is for informational purposes only and should not be considered financial advice. Investment decisions should be based on thorough research and consultation with a qualified financial advisor. Data is based on publicly available information and may not be completely accurate or up-to-date. Market share estimations are subjective.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Shuttle Pharmaceuticals Inc

Exchange NASDAQ
Headquaters Gaithersburg, MD, United States
IPO Launch date 2022-08-31
CEO -
Sector Healthcare
Industry Drug Manufacturers - Specialty & Generic
Full time employees 9
Full time employees 9

Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. The company is developing Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas; and SP-2-225, a pre-clinical class IIb product candidate that effects on the regulation of the immune system. It is also developing SP-1-303, a pre-clinical selective Class I HDAC for use in the treatment of ER positive breast cancers; and SP-1-161, a HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway. The company was founded in 2012 and is headquartered in Gaithersburg, Maryland.