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Upturn AI SWOT - About
Shuttle Pharmaceuticals Inc (SHPH)

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Upturn Advisory Summary
10/23/2025: SHPH (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -44.09% | Avg. Invested days 17 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 37.68M USD | Price to earnings Ratio - | 1Y Target Price - |
Price to earnings Ratio - | 1Y Target Price - | ||
Volume (30-day avg) - | Beta 0.41 | 52 Weeks Range 3.00 - 107.40 | Updated Date 06/29/2025 |
52 Weeks Range 3.00 - 107.40 | Updated Date 06/29/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -69.25 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -115.05% | Return on Equity (TTM) -346.2% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 34845478 | Price to Sales(TTM) - |
Enterprise Value 34845478 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.67 | Shares Outstanding 10984300 | Shares Floating 411243 |
Shares Outstanding 10984300 | Shares Floating 411243 | ||
Percent Insiders 5.82 | Percent Institutions 0.94 |
Upturn AI SWOT
Shuttle Pharmaceuticals Inc
Company Overview
History and Background
Shuttle Pharmaceuticals, Inc. is a pharmaceutical company focused on improving the outcomes of cancer patients treated with radiation therapy. Founded with a focus on developing proprietary formulations to enhance cancer treatment effectiveness and reduce side effects.
Core Business Areas
- Drug Development: Focuses on the development of novel therapeutic candidates designed to improve cancer treatment outcomes by protecting normal tissue during radiation therapy.
- Clinical Trials: Conducting clinical trials to evaluate the safety and efficacy of its drug candidates.
- Partnerships: Forming strategic alliances with research institutions and pharmaceutical companies.
Leadership and Structure
The leadership team comprises experienced professionals in drug development, clinical research, and business management. Organizational structure includes scientific advisory board and executive management.
Top Products and Market Share
Key Offerings
- Ropidoxuridine: A lead drug candidate designed to protect normal tissue during cancer radiation therapy. Market share is currently 0% as it is still in development. Competitors include companies developing similar radioprotective agents or improving radiation delivery techniques.
- SP-1-164: Another drug candidate in preclinical development, with similar intended use. Market share 0%. Competitors include companies developing similar radioprotective agents or improving radiation delivery techniques.
Market Dynamics
Industry Overview
The pharmaceutical industry, particularly in oncology and radioprotection, is highly competitive and regulated, with significant research and development investments and strict regulatory approval processes.
Positioning
Shuttle Pharmaceuticals is positioned as a company developing novel radioprotective agents. Its competitive advantage lies in its proprietary formulations and targeted approach to reducing radiation-induced side effects.
Total Addressable Market (TAM)
The total addressable market for radioprotective agents is estimated to be in the billions, growing with increasing cancer incidence and radiation therapy usage. Shuttle Pharmaceuticals is positioned to capture a segment of this market with successful drug development and commercialization.
Upturn SWOT Analysis
Strengths
- Novel drug candidates with a targeted mechanism of action
- Experienced leadership team
- Focus on unmet medical need in radioprotection
- Strong IP portfolio
Weaknesses
- Early-stage development with significant regulatory and clinical risks
- Limited financial resources
- Dependence on successful clinical trial outcomes
- No current revenue streams
Opportunities
- Potential for breakthrough therapy designation
- Partnerships with larger pharmaceutical companies
- Expansion into new cancer indications
- Government grants and funding opportunities
Threats
- Clinical trial failures
- Regulatory hurdles
- Competition from established pharmaceutical companies
- Patent challenges
Competitors and Market Share
Key Competitors
- POLA
- GTBP
- JANX
Competitive Landscape
Shuttle Pharmaceuticals competes with other pharmaceutical companies developing radiation therapy drugs and companies offering radiation therapy techniques. The competitive landscape is characterized by innovation, regulatory requirements, and a focus on improved patient outcomes.
Growth Trajectory and Initiatives
Historical Growth: Historical growth is characterized by the development of drugs, rather than revenue generation.
Future Projections: Future growth is contingent on successful clinical trial outcomes and regulatory approvals.
Recent Initiatives: Recent initiatives include advancing the clinical development of Ropidoxuridine and SP-1-164, and seeking strategic partnerships.
Summary
Shuttle Pharmaceuticals is a development-stage pharmaceutical company with promising drug candidates for radioprotection in cancer therapy. The company's success hinges on positive clinical trial results and regulatory approvals. Its strengths are in novel drug development, while weaknesses lie in its early-stage status and limited resources. The company should capitalize on partnership opportunities and mitigate clinical and regulatory risks.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company website
- SEC filings
- Third-party market research reports
Disclaimers:
This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be made based on thorough research and consultation with a qualified financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Shuttle Pharmaceuticals Inc
Exchange NASDAQ | Headquaters Gaithersburg, MD, United States | ||
IPO Launch date 2022-08-31 | CEO - | ||
Sector Healthcare | Industry Drug Manufacturers - Specialty & Generic | Full time employees 9 | Website https://www.shuttlepharma.com |
Full time employees 9 | Website https://www.shuttlepharma.com | ||
Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. The company is developing Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas; and SP-2-225, a pre-clinical class IIb product candidate that effects on the regulation of the immune system. It is also developing SP-1-303, a pre-clinical selective Class I HDAC for use in the treatment of ER positive breast cancers; and SP-1-161, a HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway. The company was founded in 2012 and is headquartered in Gaithersburg, Maryland.

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