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Sellas Life Sciences Group Inc (SLS)

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Upturn Advisory Summary
01/09/2026: SLS (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $6.83
1 Year Target Price $6.83
| 2 | Strong Buy |
| 1 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -51.32% | Avg. Invested days 20 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 589.18M USD | Price to earnings Ratio - | 1Y Target Price 6.83 |
Price to earnings Ratio - | 1Y Target Price 6.83 | ||
Volume (30-day avg) 3 | Beta 2.27 | 52 Weeks Range 0.85 - 5.18 | Updated Date 01/9/2026 |
52 Weeks Range 0.85 - 5.18 | Updated Date 01/9/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.28 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -44.9% | Return on Equity (TTM) -84.33% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 613567620 | Price to Sales(TTM) 26.9 |
Enterprise Value 613567620 | Price to Sales(TTM) 26.9 | ||
Enterprise Value to Revenue 20.84 | Enterprise Value to EBITDA -1.71 | Shares Outstanding 170282026 | Shares Floating 141749970 |
Shares Outstanding 170282026 | Shares Floating 141749970 | ||
Percent Insiders 0.26 | Percent Institutions 23.69 |
Upturn AI SWOT
Sellas Life Sciences Group Inc
Company Overview
History and Background
Sellas Life Sciences Group Inc. (NASDAQ: SLS) is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel cancer immunotherapies. The company was founded with the goal of addressing unmet medical needs in oncology by leveraging its proprietary technology platforms. Key milestones include advancing its lead product candidates through clinical trials and establishing strategic partnerships.
Core Business Areas
- Oncology Therapeutics Development: Focuses on the research, development, and clinical testing of novel immunotherapies for various types of cancer. This includes drug discovery, preclinical studies, clinical trial management, and regulatory submissions.
Leadership and Structure
Sellas Life Sciences Group Inc. is led by a management team with expertise in drug development, oncology, and business operations. The organizational structure is typical of a biopharmaceutical company, with departments dedicated to research and development, clinical affairs, regulatory affairs, manufacturing, and commercial operations.
Top Products and Market Share
Key Offerings
- Competitors: Various companies developing WT1-targeted therapies or other immunotherapies for mesothelioma and AML.
- Description: GPS is a novel cancer immunotherapy targeting Wilms Tumor 1 (WT1) protein, which is expressed in various hematologic malignancies and solid tumors. It is being developed for indications such as malignant pleural mesothelioma and acute myeloid leukemia (AML). Competitors in the WT1 targeting space are emerging, but GPS is considered a differentiated approach.
- Market Share Data: N/A (Clinical-stage product, no current market share)
- Product Name 1: Galinpepimut-S (GPS)
- Competitors: Other companies developing personalized cancer vaccines or advanced immunotherapies.
- Description: A personalized dendritic cell vaccine approach for cancer treatment. The specific indications and development status may vary.
- Market Share Data: N/A (Clinical-stage product, no current market share)
- Product Name 2: Dendritic Cell Vaccine (DCV)
Market Dynamics
Industry Overview
The oncology therapeutics market is a rapidly growing and highly competitive sector driven by advancements in immunotherapy, targeted therapies, and personalized medicine. There is a significant unmet need for effective treatments for many advanced cancers, leading to substantial investment in research and development.
Positioning
Sellas Life Sciences Group Inc. is positioned as a clinical-stage biopharmaceutical company focused on innovative cancer immunotherapies. Its competitive advantages lie in its proprietary technology platforms and its focus on specific unmet needs within the oncology landscape. However, as a clinical-stage company, it faces challenges related to clinical trial success and regulatory approval.
Total Addressable Market (TAM)
The TAM for oncology therapeutics is vast, estimated to be in the hundreds of billions of dollars globally. Sellas Life Sciences Group Inc. targets specific sub-segments within this market, such as mesothelioma and AML, where there are significant unmet needs and potential for substantial market penetration upon successful development and commercialization of its products.
Upturn SWOT Analysis
Strengths
- Focus on novel cancer immunotherapies.
- Proprietary technology platforms.
- Experienced management team.
- Potential for differentiated treatment options.
Weaknesses
- Clinical-stage company with no approved products.
- Reliance on successful clinical trials and regulatory approvals.
- Limited financial resources compared to larger pharmaceutical companies.
- High risk associated with drug development.
Opportunities
- Growing demand for effective cancer treatments.
- Advancements in immunotherapy research.
- Potential for strategic partnerships and collaborations.
- Expansion into new oncology indications.
Threats
- Failure of clinical trials.
- Regulatory hurdles and delays.
- Intense competition in the oncology market.
- Pricing pressures and market access challenges.
- Intellectual property challenges.
Competitors and Market Share
Key Competitors
- Merck & Co., Inc. (MRK)
- Bristol-Myers Squibb Company (BMY)
- Roche Holding AG (RHHBY)
- Moderna, Inc. (MRNA)
Competitive Landscape
Sellas Life Sciences Group Inc. operates in a highly competitive landscape dominated by large pharmaceutical companies with significant R&D budgets and established market presence. Its advantage lies in its focus on niche indications and potentially novel mechanisms of action. However, it faces challenges in competing for resources, talent, and market share against these giants.
Growth Trajectory and Initiatives
Historical Growth: Historical growth for Sellas Life Sciences Group Inc. is characterized by its progression through preclinical and clinical development stages, and fundraising activities to support these efforts.
Future Projections: Future growth projections are heavily contingent on the successful development and commercialization of its product candidates, particularly Galinpepimut-S. Analyst estimates would focus on potential peak sales based on market penetration assumptions.
Recent Initiatives: Recent initiatives likely involve advancing clinical trials for its lead candidates, seeking regulatory feedback, and potentially exploring strategic collaborations or partnerships to accelerate development or commercialization.
Summary
Sellas Life Sciences Group Inc. is a clinical-stage biopharmaceutical company with promising, yet unproven, cancer immunotherapies. Its strengths lie in its innovative approach and focus on unmet needs. However, its clinical-stage nature presents significant risks, including reliance on trial success and regulatory approvals, and limited financial resources. The company needs to successfully navigate clinical development and secure substantial funding to overcome these hurdles and capitalize on the substantial opportunities within the growing oncology market.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company SEC Filings (e.g., 10-K, 10-Q)
- Financial News Outlets
- Industry Analysis Reports
- Company Investor Relations
Disclaimers:
This JSON output is for informational purposes only and does not constitute financial advice. Market share data for clinical-stage companies is often estimated or indicative. Financial performance details should be verified through official SEC filings. The AI-based rating is an automated assessment and should not be the sole basis for investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Sellas Life Sciences Group Inc
Exchange NASDAQ | Headquaters New York, NY, United States | ||
IPO Launch date 2017-12-29 | Founder, President, CEO & Director Dr. Angelos M. Stergiou M.D., ScD h.c. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 15 | |
Full time employees 15 | |||
SELLAS Life Sciences Group, Inc., a late-stage clinical biopharmaceutical company, focuses on the development of novel therapeutics for various cancer indications in the United States. The company's lead product candidate is galinpepimut-S (GPS), a peptide immunotherapy directed against the Wilms tumor 1, antigen; and SLS009 (tambiciclib), a selective small molecule cyclin-dependent kinase 9, or CDK9, inhibitor. It has a strategic collaboration with Merck & Co., Inc. to evaluate GPS as it is administered in combination with PD1 blocker pembrolizumab in a Phase 1/2 clinical trial enrolling patients in up to five cancer indications, including hematologic malignancies and solid tumors; and GenFleet Therapeutics (Shanghai), Inc. for the development and commercialization of GFH009. SELLAS Life Sciences Group, Inc. is headquartered in New York, New York.

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