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Upturn AI Summary - About
Sutro Biopharma(STRO)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for STRO
10/23/2026: STRO (1-star) is currently NOT-A-BUY. Pass it for now.
Sutro Biopharma is a clinical-stage biotechnology company developing cancer therapies using its proprietary cell-free protein synthesis platform. The firm is recognized for its technical precision in engineering antibody-drug conjugates, which are a major area of focus in oncology. Its primary investment story rests on the potential clinical success of its lead candidates, including Luvelta. However, investors face significant risks related to clinical trial outcomes, a high cash burn rate, and intense competition from much larger, well-capitalized pharmaceutical firms. The stock is most suitable for investors comfortable with high-risk, high-reward profiles and should be monitored closely for data readouts and ongoing partnership milestones.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company offers high-growth potential linked to clinical success but carries substantial risk of volatility. |
| Momentum investor | Mixed fit | Momentum is highly conditional on clinical trial data readouts and positive news cycles. |
| Value investor | Weak fit | As a loss-making clinical-stage firm, there are no traditional earnings-based valuation metrics. |
| Dividend investor | Weak fit | The company does not pay dividends and prioritizes cash for R&D. |
| Low-risk investor | Weak fit | The high inherent risk of clinical-stage biotechnology makes this unsuitable for low-risk portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Stock price is extremely sensitive to clinical trial outcomes and biotech sector sentiment. |
| Valuation risk | High | Determining fair value is difficult given the lack of current commercial revenue. |
| Competition risk (Big Pharma dominance) | High | Established companies hold significant market share and resources in the ADC space. |
| Business quality | Medium | While the platform technology is well-regarded, the business model is unproven at a commercial scale. |
| Dividend income | Low / none | No income is generated for shareholders. |
| Execution risk | High | Successfully managing clinical trials and regulatory pathways is complex and prone to delay. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Highly Choppy
The stock has experienced frequent, large price swings that make its near-term movement less predictable.
Analysis of Past Performance
Type Stock | Historic Profit -9.22% | Avg. Invested days 29 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 10/23/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 170.62M USD | Price to earnings Ratio - | 1Y Target Price 47.23 |
Price to earnings Ratio - | 1Y Target Price 47.23 | ||
Volume (30-day avg) 345.6K shares | Beta 1.5 | 52 Weeks Range 7.15 - 43.85 | Updated Date 10/22/2026 |
52 Weeks Range 7.15 - 43.85 | Updated Date 10/22/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -16.46 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Collaboration and Licensing Revenue | Milestone payments and royalties from partnership agreements involving the cell-free platform. | Revenue is not from commercial drug sales, but from corporate partners paying for access to Sutro's technology. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE - | Forward PE 10.03 | Enterprise Value 113.89M | Price to Sales(TTM) 3.73 |
Enterprise Value 113.89M | Price to Sales(TTM) 3.73 | ||
Enterprise Value to Revenue 2.48 | Enterprise Value to EBITDA 41.71 | Shares Outstanding 16.58M | Shares Floating 10.76M |
Shares Outstanding 16.58M | Shares Floating 10.76M | ||
Percent Insiders 2.26 | Percent Institutions 99.01 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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