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Upturn AI SWOT - About
TGTX 
TG Therapeutics Inc (TGTX)
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Upturn Advisory Summary
06/18/2025: TGTX (1-star) is currently NOT-A-BUY. Pass it for now.
Upturn Star Rating
Not Recommended Performance
These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.
Analysis of Past Performance
Type Stock | Historic Profit 35.53% | Avg. Invested days 28 | Today’s Advisory PASS |
Upturn Star Rating | Upturn Advisory Performance  3.0 | Stock Returns Performance  3.0 |
| Profits based on simulation | Last Close 06/18/2025 |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 5.58B USD | Price to earnings Ratio 140.66 | 1Y Target Price 41.2 |
Price to earnings Ratio 140.66 | 1Y Target Price 41.2 | ||
Volume (30-day avg) 1943978 | Beta 1.94 | 52 Weeks Range 16.65 - 46.48 | Updated Date 06/19/2025 |
52 Weeks Range 16.65 - 46.48 | Updated Date 06/19/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) 0.25 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin 10.13% | Operating Margin (TTM) 7.13% |
Management Effectiveness
Return on Assets (TTM) 7.26% | Return on Equity (TTM) 19.7% |
Valuation
Trailing PE 140.66 | Forward PE 25.32 | Enterprise Value 5458341840 | Price to Sales(TTM) 14.45 |
Enterprise Value 5458341840 | Price to Sales(TTM) 14.45 | ||
Enterprise Value to Revenue 14.13 | Enterprise Value to EBITDA 77.43 | Shares Outstanding 158755008 | Shares Floating 135060602 |
Shares Outstanding 158755008 | Shares Floating 135060602 | ||
Percent Insiders 9.74 | Percent Institutions 63.24 |
Analyst Ratings
Rating 4.43 | Target Price 41.2 | Buy 1 | Strong Buy 5 |
Buy 1 | Strong Buy 5 | ||
Hold - | Sell 1 | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
TG Therapeutics Inc
Company Overview
History and Background
TG Therapeutics, Inc. was founded in 1993 and is focused on the acquisition, development, and commercialization of novel treatments for B-cell malignancies and autoimmune diseases.
Core Business Areas
- Hematological Oncology: Focuses on developing and commercializing therapies for B-cell malignancies such as lymphoma and leukemia.
- Autoimmune Diseases: Expanding focus on developing therapies for autoimmune diseases. This segment is currently more limited.
Leadership and Structure
Michael S. Weiss is the Executive Chairman and CEO. The company has a typical structure with research, development, commercial, and administrative departments.
Top Products and Market Share
Key Offerings
- Ublituximab (Briumvi): An anti-CD20 monoclonal antibody approved for relapsing forms of multiple sclerosis (RMS). Revenue and market share data are still developing. Competitors include Ocrevus (Roche), Kesimpta (Novartis), and Mayzent (Novartis).
Market Dynamics
Industry Overview
The pharmaceutical industry, specifically in oncology and autoimmune disease, is highly competitive and heavily regulated. It is characterized by high R&D costs, long development timelines, and patent protection.
Positioning
TG Therapeutics is a smaller player competing with larger, more established pharmaceutical companies. Briumvi gives them a competitive advantage in the RMS market segment.
Total Addressable Market (TAM)
The TAM for multiple sclerosis therapies is estimated at $25-30 billion annually. TG Therapeutics' is focused on carving out share within the RMS sub-segment.
Upturn SWOT Analysis
Strengths
- FDA Approved Product (Briumvi)
- Focused Therapeutic Areas
- Experienced Management Team
- Novel Antibody Technology
Weaknesses
- Limited Product Portfolio
- High Debt Levels
- Reliance on Single Product Revenue
- Smaller Commercial Infrastructure Compared to Competitors
Opportunities
- Expansion of Briumvi into New Indications
- Strategic Partnerships and Acquisitions
- Growth in the Autoimmune Disease Market
- Positive Clinical Trial Results
Threats
- Competition from Established Pharmaceutical Companies
- Regulatory Hurdles
- Patent Expiry
- Unfavorable Reimbursement Policies
- Adverse Events or Safety Concerns with Briumvi
Competitors and Market Share
Key Competitors
- RHHBY
- NVS
Competitive Landscape
TG Therapeutics faces strong competition from larger pharmaceutical companies. While Briumvi offers a novel mechanism of action, competitors have established market presence and strong brand recognition.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth has been driven by clinical trial successes and regulatory approvals.
Future Projections: Future growth is dependent on the commercial success of Briumvi and the advancement of other pipeline candidates. Analyst estimates vary based on these factors.
Recent Initiatives: Recent initiatives include the commercial launch of Briumvi, and continued clinical trials in autoimmune disease.
Summary
TG Therapeutics is a biotechnology company with one approved product, Briumvi, targeting the RMS market. The company faces strong competition and relies heavily on the success of Briumvi. Future growth depends on expanding Briumvi's indications, securing strategic partnerships, and overcoming regulatory and competitive hurdles. High debt levels and reliance on single product revenues remain significant challenges.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports
- Press Releases
Disclaimers:
This analysis is for informational purposes only and should not be considered investment advice. Financial data is subject to change and may not be entirely accurate. Consult with a financial professional before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About TG Therapeutics Inc
Exchange NASDAQ | Headquaters Morrisville, NC, United States | ||
IPO Launch date 1995-12-14 | Chairman, CEO & President Mr. Michael S. Weiss Esq. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 352 | Website https://www.tgtherapeutics.com |
Full time employees 352 | Website https://www.tgtherapeutics.com | ||
TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally. It provides BRIUMVI, an anti-CD20 monoclonal antibody for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. The company's development pipeline comprises Ublituximab IV, glycoengineered anti-CD20 mAb for the treatment of relapsing MS; TG-1701 is an orally available and covalently bound Bruton's tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK in vitro kinase screening; and TG-1801, a bispecific CD47 and CD19 antibody. Its research pipeline includes various investigational medicines. The company has license agreements with LFB Biotechnologies S.A.S; GTC Biotherapeutics; LFB/GTC LLC; Ildong Pharmaceutical Co. Ltd.; Rhizen Pharmaceuticals, S A. for the development and commercialization of umbralisib; Jiangsu Hengrui Medicine Co.; and Novimmune SA, as well as collaboration agreement with Checkpoint Therapeutics, Inc. for the development and commercialization of anti-PD-L1 and anti-GITR antibody research programs in the field of hematological malignancies. The company was incorporated in 1993 and is based in Morrisville, North Carolina.
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