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Immunome Inc (IMNM)

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Upturn Advisory Summary
01/09/2026: IMNM (2-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $34.25
1 Year Target Price $34.25
| 7 | Strong Buy |
| 2 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 2.13% | Avg. Invested days 25 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 2.26B USD | Price to earnings Ratio - | 1Y Target Price 34.25 |
Price to earnings Ratio - | 1Y Target Price 34.25 | ||
Volume (30-day avg) 9 | Beta 2.23 | 52 Weeks Range 5.15 - 25.30 | Updated Date 01/9/2026 |
52 Weeks Range 5.15 - 25.30 | Updated Date 01/9/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.96 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -2137.1% |
Management Effectiveness
Return on Assets (TTM) -46.48% | Return on Equity (TTM) -93.04% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 1987730414 | Price to Sales(TTM) 233.12 |
Enterprise Value 1987730414 | Price to Sales(TTM) 233.12 | ||
Enterprise Value to Revenue 205.37 | Enterprise Value to EBITDA -0.72 | Shares Outstanding 110335277 | Shares Floating 86622191 |
Shares Outstanding 110335277 | Shares Floating 86622191 | ||
Percent Insiders 7.85 | Percent Institutions 82.04 |
Upturn AI SWOT
Immunome Inc

Company Overview
History and Background
Immunome Inc. was founded in 2017 and is a biotechnology company focused on developing antibody therapeutics. It has progressed from its early stages of research and development to establishing a pipeline of potential drug candidates, leveraging its proprietary technology platforms.
Core Business Areas
- Antibody Therapeutics Development: Immunome's core business revolves around the discovery and development of highly potent and selective antibody therapeutics. They utilize their AI-driven platform to identify novel antibody candidates targeting various diseases, with a particular focus on oncology and autoimmune disorders.
Leadership and Structure
Information on Immunome Inc.'s current leadership team and specific organizational structure can be found on their official investor relations pages and SEC filings. The company operates under a typical biotech structure with R&D, clinical operations, and corporate functions.
Top Products and Market Share
Key Offerings
- ONC-389 (Anti-IL-33 Antibody): ONC-389 is a potential first-in-class antibody therapeutic targeting IL-33, a cytokine implicated in various inflammatory conditions and certain cancers. It is currently in preclinical development. Competitors in the IL-33 space include companies developing small molecule inhibitors or other antibody-based therapies.
- ONC-466 (Anti-CD73 Antibody): ONC-466 is an antibody targeting CD73, an ectonucleotidase that plays a role in the tumor microenvironment and immune suppression. This candidate is also in preclinical development. Key competitors in the CD73 space include those developing small molecule inhibitors and other monoclonal antibodies.
Market Dynamics
Industry Overview
The biotechnology sector, particularly antibody therapeutics, is a rapidly growing and dynamic industry driven by advancements in genomics, AI, and a persistent need for novel treatments for cancer and autoimmune diseases. The market is characterized by high R&D costs, long development cycles, and significant regulatory hurdles.
Positioning
Immunome positions itself as a leader in antibody discovery by leveraging advanced AI and machine learning to identify and develop differentiated antibody therapeutics. Their proprietary platform aims to accelerate the discovery process and identify antibodies with superior potency and selectivity compared to traditional methods. Their competitive advantage lies in their technological approach to drug discovery.
Total Addressable Market (TAM)
The TAM for antibody therapeutics is substantial and growing, encompassing various therapeutic areas including oncology, immunology, and infectious diseases, projected to be in the hundreds of billions of dollars globally. Immunome is positioned to address segments of this TAM with its pipeline, though its current market share is negligible as its products are in early development.
Upturn SWOT Analysis
Strengths
- Proprietary AI-driven antibody discovery platform
- Focus on well-validated but underserved targets
- Experienced scientific and management team
- Potential for highly potent and selective antibody candidates
Weaknesses
- Early-stage pipeline with no approved products
- Significant reliance on future clinical success and funding
- Limited historical financial track record
- High burn rate typical of biotech companies
Opportunities
- Partnerships and collaborations with larger pharmaceutical companies
- Expansion of pipeline into new therapeutic areas
- Advancements in AI and machine learning enhancing discovery capabilities
- Growing demand for novel cancer and autoimmune treatments
Threats
- Clinical trial failures or delays
- Intense competition from established and emerging biotech firms
- Changes in regulatory landscape
- Challenges in securing future funding
- Patent disputes and intellectual property challenges
Competitors and Market Share
Key Competitors
- Regeneron Pharmaceuticals (REGN)
- Amgen Inc. (AMGN)
- Bristol Myers Squibb Company (BMY)
- Roche Holding AG (RHHBY)
Competitive Landscape
Immunome competes in a highly competitive landscape with large, established pharmaceutical companies and numerous smaller biotech firms all vying for market share in antibody therapeutics. Immunome's advantage lies in its novel AI-driven discovery platform, which aims to identify unique and potent antibodies more efficiently than traditional methods. However, it faces disadvantages in terms of established manufacturing capabilities, clinical trial infrastructure, and market access that larger competitors possess.
Growth Trajectory and Initiatives
Historical Growth: Immunome's historical growth has been characterized by the expansion of its R&D capabilities, the growth of its scientific team, and the advancement of its pipeline from discovery to preclinical stages. The company has also grown through its ability to secure funding for its operations.
Future Projections: Future projections for Immunome are contingent upon the successful clinical development and potential commercialization of its antibody candidates. Analyst estimates would typically focus on the potential market size for its lead programs and the probability of success in clinical trials.
Recent Initiatives: Recent initiatives likely include progress in preclinical studies for its lead drug candidates (ONC-389 and ONC-466), potential strategic partnerships, and ongoing efforts to secure funding to support its development programs.
Summary
Immunome Inc. is an early-stage biotechnology company with a promising AI-driven platform for antibody discovery. Its strengths lie in its technology and scientific expertise, while its weaknesses include an unproven pipeline and significant funding requirements. The company has opportunities for growth through strategic partnerships and market expansion, but faces threats from clinical failures and intense competition. Continued progress in its preclinical programs and successful funding rounds will be crucial for its future.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company Investor Relations Websites
- SEC Filings (10-K, 10-Q, S-1)
- Industry Research Reports
- Financial News Outlets
Disclaimers:
This JSON output is an analysis based on publicly available information. It is not financial advice. Investors should conduct their own due diligence before making any investment decisions. Market share data for early-stage companies like Immunome is often theoretical or based on potential rather than actual realized market share. Competitor market share data is illustrative and may vary depending on the specific market segment analyzed.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Immunome Inc
Exchange NASDAQ | Headquaters Bothell, WA, United States | ||
IPO Launch date 2020-10-02 | Chairman, President & CEO Dr. Clay B. Siegall Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 168 | Website https://immunome.com |
Full time employees 168 | Website https://immunome.com | ||
Immunome, Inc., a clinical-stage biotechnology company, develops targeted cancer therapies. The company's clinical asset comprises Varegacestat, a gamma secretase inhibitor that is in Phase 3 clinical trial for the treatment of desmoid tumors; and IM-1021, a receptor tyrosine kinase-like orphan receptor 1 antibody-drug conjugate (ADC), which is in Phase 1 clinical trial. Its preclinical assets include IM-3050, a fibroblast activation protein targeted radioligand therapy; and solid tumor ADC drug candidates, including IM-1617, IM-1340, and IM-1335. Immunome, Inc. was incorporated in 2006 and is based in Bothell, Washington.

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