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Immunome Inc (IMNM)



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Upturn Advisory Summary
06/30/2025: IMNM (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $24.5
1 Year Target Price $24.5
7 | Strong Buy |
2 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -34.44% | Avg. Invested days 20 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 763.10M USD | Price to earnings Ratio - | 1Y Target Price 24.5 |
Price to earnings Ratio - | 1Y Target Price 24.5 | ||
Volume (30-day avg) 9 | Beta 1.95 | 52 Weeks Range 5.15 - 16.81 | Updated Date 06/30/2025 |
52 Weeks Range 5.15 - 16.81 | Updated Date 06/30/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -3.01 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -1525.5% |
Management Effectiveness
Return on Assets (TTM) -33.54% | Return on Equity (TTM) -69.21% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 451415239 | Price to Sales(TTM) 69.77 |
Enterprise Value 451415239 | Price to Sales(TTM) 69.77 | ||
Enterprise Value to Revenue 41.27 | Enterprise Value to EBITDA -0.72 | Shares Outstanding 87012304 | Shares Floating 69498487 |
Shares Outstanding 87012304 | Shares Floating 69498487 | ||
Percent Insiders 11.48 | Percent Institutions 83.28 |
Analyst Ratings
Rating 3 | Target Price 24.5 | Buy 2 | Strong Buy 7 |
Buy 2 | Strong Buy 7 | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Immunome Inc

Company Overview
History and Background
Immunome, Inc. was founded in 2015 and is headquartered in Exton, Pennsylvania. It is a clinical-stage biotechnology company focused on developing novel antibody-based therapeutics for the treatment of cancer. They leverage their proprietary discovery engine to analyze and decode the human immune system.
Core Business Areas
- Drug Discovery and Development: Focuses on identifying and developing antibody-based therapeutics targeting cancer and infectious diseases.
- Platform Technology: Leverages its proprietary human memory B cell platform to discover and develop novel antibodies.
- Partnering: Engages in collaborations with other biotech and pharmaceutical companies.
Leadership and Structure
The leadership team includes Clay B. Siegall, Ph.D. (Chairman & CEO), Scott A. Brown (Chief Financial Officer), and Dr. Jan Ter Meulen (Chief Scientific Officer). The organizational structure is typical for a biotech company with research, development, clinical, and administrative departments.
Top Products and Market Share
Key Offerings
- Lytic Antibodies: These antibodies are designed to directly kill cancer cells. While specific market share data is not available, competitors include companies developing similar antibody therapeutics such as Genmab (GMAB) and Seagen (SGEN), now part of Pfizer (PFE).
- Checkpoint Inhibitors: These are novel checkpoint inhibitors designed to modulate the immune response against cancer. Competitors include major pharmaceutical companies like Merck (MRK) with Keytruda and Bristol-Myers Squibb (BMY) with Opdivo. Market share varies with stage of clinical trial and approval.
Market Dynamics
Industry Overview
The biotechnology industry is characterized by intense competition, high research and development costs, and a lengthy regulatory approval process. The focus is on developing novel therapies for unmet medical needs, including cancer and infectious diseases.
Positioning
Immunome is positioned as an innovative company focused on leveraging its antibody discovery platform to develop unique therapeutic candidates. Their competitive advantage lies in their approach to identifying and validating novel targets through the study of human immune responses.
Total Addressable Market (TAM)
The TAM for cancer therapeutics is estimated to be in the hundreds of billions of dollars. Immunome is targeting specific niches within this market with novel antibody-based therapies and checkpoint inhibitors, positioning themselves to potentially capture a significant portion of relevant markets upon successful commercialization.
Upturn SWOT Analysis
Strengths
- Proprietary antibody discovery platform
- Novel therapeutic candidates
- Experienced leadership team
Weaknesses
- Limited financial resources
- Dependence on clinical trial outcomes
- Early stage company
Opportunities
- Partnerships and collaborations
- Expansion of therapeutic pipeline
- Favorable regulatory environment
Threats
- Competition from larger pharmaceutical companies
- Clinical trial failures
- Regulatory hurdles
Competitors and Market Share
Key Competitors
- MRK
- BMY
- GMAB
- PFE
Competitive Landscape
Immunome faces intense competition from established pharmaceutical companies with significantly greater resources. Their advantage lies in their innovative antibody discovery platform, which could lead to differentiated therapeutic candidates. However, they need to overcome the challenges of clinical development and commercialization to compete effectively.
Growth Trajectory and Initiatives
Historical Growth: Immunome's historical growth is characterized by pipeline development and clinical trial progress.
Future Projections: Future projections are dependent on clinical trial outcomes and potential partnerships. Analyst estimates, available from financial data providers, provide insights into projected revenue and earnings.
Recent Initiatives: Recent initiatives include advancing clinical trials for lead therapeutic candidates and expanding collaborations to broaden the therapeutic pipeline.
Summary
Immunome is an early-stage biotech company with a promising antibody discovery platform. They face significant competition and financial constraints, but their innovative approach and experienced leadership team offer potential for future growth. Successful clinical trial outcomes and strategic partnerships will be crucial for their success, and they should closely manage cash flow to support R&D.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Financial News Outlets
- Analyst Reports (General Information)
Disclaimers:
This analysis is for informational purposes only and should not be considered financial advice. Market share data is estimated and may vary. Clinical trial outcomes are inherently uncertain. Consult with a qualified financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Immunome Inc
Exchange NASDAQ | Headquaters Bothell, WA, United States | ||
IPO Launch date 2020-10-02 | Chairman, President & CEO Dr. Clay B. Siegall Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 131 | Website https://immunome.com |
Full time employees 131 | Website https://immunome.com |
Immunome, Inc., a clinical-stage biotechnology company, develops targeted cancer therapies. The company's clinical asset comprises Varegacestat, a gamma secretase inhibitor that is in Phase 3 clinical trial for the treatment of desmoid tumors; and IM-1021, a receptor tyrosine kinase-like orphan receptor 1 antibody-drug conjugate (ADC), which is in Phase 1 clinical trial. Its preclinical assets include IM-3050, a fibroblast activation protein targeted radioligand therapy; and solid tumor ADC drug candidates, including IM-1617, IM-1340, and IM-1335. Immunome, Inc. was incorporated in 2006 and is based in Bothell, Washington.
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