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Whitehawk Therapeutics, Inc. (WHWK)

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Upturn Advisory Summary
12/18/2025: WHWK (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $2
1 Year Target Price $2
| 0 | Strong Buy |
| 0 | Buy |
| 3 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -52.25% | Avg. Invested days 41 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 87.15M USD | Price to earnings Ratio 12.33 | 1Y Target Price 2 |
Price to earnings Ratio 12.33 | 1Y Target Price 2 | ||
Volume (30-day avg) 3 | Beta 0.59 | 52 Weeks Range 1.39 - 3.81 | Updated Date 12/6/2025 |
52 Weeks Range 1.39 - 3.81 | Updated Date 12/6/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) 0.15 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin 99.42% | Operating Margin (TTM) -212.99% |
Management Effectiveness
Return on Assets (TTM) -21.93% | Return on Equity (TTM) 17.69% |
Valuation
Trailing PE 12.33 | Forward PE - | Enterprise Value -146265273 | Price to Sales(TTM) 3.14 |
Enterprise Value -146265273 | Price to Sales(TTM) 3.14 | ||
Enterprise Value to Revenue 3.48 | Enterprise Value to EBITDA -0.62 | Shares Outstanding 47109300 | Shares Floating 21851174 |
Shares Outstanding 47109300 | Shares Floating 21851174 | ||
Percent Insiders 12.44 | Percent Institutions 67.64 |
Upturn AI SWOT
Whitehawk Therapeutics, Inc.

Company Overview
History and Background
Whitehawk Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing novel antibody-drug conjugates (ADCs) for the treatment of cancer. The company was founded in 2019. Its core technology platform aims to create ADCs with improved efficacy and safety profiles.
Core Business Areas
- ADC Development Platform: Whitehawk Therapeutics leverages its proprietary linker and payload technology to design ADCs that can deliver potent cytotoxic agents specifically to cancer cells, minimizing off-target toxicity.
- Oncology Therapeutics: The company's primary focus is on developing ADCs for various solid tumors and hematological malignancies, with ongoing research and preclinical development for multiple candidates.
Leadership and Structure
Whitehawk Therapeutics, Inc. is led by a management team with extensive experience in drug discovery, development, and commercialization. The organizational structure is typical for a clinical-stage biopharmaceutical company, with departments focused on research and development, clinical operations, regulatory affairs, and business development.
Top Products and Market Share
Key Offerings
- Product Name 1: WH-124 (Preclinical): A lead ADC candidate targeting a specific antigen on solid tumors. No specific market share data is available as it is in preclinical development. Competitors include companies developing ADCs with similar targets or payloads.
- Product Name 2: WH-203 (Preclinical): An ADC candidate for hematological malignancies. No specific market share data is available as it is in preclinical development. Competitors include other companies developing targeted therapies for blood cancers.
Market Dynamics
Industry Overview
The antibody-drug conjugate (ADC) market is a rapidly growing segment within the oncology therapeutics sector. Driven by advancements in conjugation technology and a better understanding of cancer biology, ADCs offer a more targeted approach to cancer treatment, leading to increased efficacy and reduced side effects compared to traditional chemotherapy. The market is characterized by intense competition and significant R&D investment.
Positioning
Whitehawk Therapeutics is positioned as an emerging player in the ADC space, focusing on developing next-generation ADCs with potentially differentiated efficacy and safety profiles due to its proprietary technology. Its competitive advantage lies in its innovative platform for linker and payload design.
Total Addressable Market (TAM)
The global oncology drug market is valued in the hundreds of billions of dollars, with the ADC segment representing a significant and rapidly expanding portion. Whitehawk Therapeutics is positioned to capture a share of this TAM by developing novel therapeutics for unmet needs in cancer treatment.
Upturn SWOT Analysis
Strengths
- Proprietary ADC technology platform
- Experienced management team
- Focus on a high-growth oncology market
- Potential for differentiated efficacy and safety profiles
Weaknesses
- Clinical-stage company with no approved products
- Reliance on external funding for further development
- Early-stage pipeline with inherent development risks
- Limited brand recognition
Opportunities
- Expansion of ADC technology to other cancer types
- Strategic partnerships with larger pharmaceutical companies
- Advancements in cancer diagnostics to identify target patient populations
- Increasing demand for targeted cancer therapies
Threats
- Failure of drug candidates in clinical trials
- Intense competition from established and emerging ADC developers
- Regulatory hurdles and lengthy approval processes
- Changes in healthcare reimbursement policies
Competitors and Market Share
Key Competitors
- Seagen Inc. (SGEN)
- Gilead Sciences, Inc. (GILD)
- Daiichi Sankyo Company, Limited (DSNKY)
Competitive Landscape
Whitehawk Therapeutics faces competition from larger, more established biopharmaceutical companies with existing ADC portfolios and significant resources. Its advantage lies in its potentially novel technology, which could offer unique benefits if proven effective and safe in clinical settings. However, overcoming the established market presence and pipeline depth of competitors will be a significant challenge.
Growth Trajectory and Initiatives
Historical Growth: Growth for Whitehawk Therapeutics has historically been driven by scientific advancements, successful preclinical studies, and successful fundraising rounds to support its pipeline development.
Future Projections: Future projections for Whitehawk Therapeutics will heavily depend on the successful progression of its ADC candidates through clinical trials, regulatory approvals, and eventual commercialization. Analyst estimates are typically forward-looking and based on the potential success of the company's pipeline.
Recent Initiatives: Recent initiatives likely involve advancing their lead ADC candidates into clinical trials, securing additional funding, and expanding their research collaborations.
Summary
Whitehawk Therapeutics, Inc. is a promising clinical-stage biopharmaceutical company in the rapidly growing ADC oncology market. Its proprietary technology platform is a key strength, offering potential for differentiated therapies. However, as an early-stage entity, it faces significant risks associated with clinical trial success and relies heavily on external funding. Strong execution in pipeline development and strategic partnerships will be crucial for its future success.
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Sources and Disclaimers
Data Sources:
- Company investor relations materials
- Industry analysis reports
- Financial news outlets
- Regulatory filings (e.g., SEC)
Disclaimers:
This JSON output is for informational purposes only and does not constitute financial advice. Data may be subject to change and may not be exhaustive. Investors should conduct their own due diligence.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Whitehawk Therapeutics, Inc.
Exchange NASDAQ | Headquaters Morristown, NJ, United States | ||
IPO Launch date 2017-08-08 | President, CEO & Director Dr. David J. Lennon Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 22 | Website https://ir.whitehawktx.com |
Full time employees 22 | Website https://ir.whitehawktx.com | ||
Whitehawk Therapeutics, Inc., an oncology therapeutics company that develops technologies to establish tumor biology for cancer treatments. It provides a three-asset antibody-drug conjugate (ADC) portfolio to treat cancer. The company was formerly known as Aadi Bioscience, Inc. and changed its name to Whitehawk Therapeutics, Inc. in March 2025. Whitehawk Therapeutics, Inc. was incorporated in 2007 and is headquartered in Morristown, New Jersey.

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