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Xenetic Biosciences Inc (XBIO)

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Upturn Advisory Summary
12/05/2025: XBIO (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $40
1 Year Target Price $40
| 0 | Strong Buy |
| 0 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -64.58% | Avg. Invested days 35 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 5.80M USD | Price to earnings Ratio - | 1Y Target Price 40 |
Price to earnings Ratio - | 1Y Target Price 40 | ||
Volume (30-day avg) 1 | Beta 2.41 | 52 Weeks Range 2.20 - 13.93 | Updated Date 12/6/2025 |
52 Weeks Range 2.20 - 13.93 | Updated Date 12/6/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.04 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
Report Date 2025-11-12 | When - | Estimate -0.84 | Actual -0.33 |
Profitability
Profit Margin -110.4% | Operating Margin (TTM) -53.04% |
Management Effectiveness
Return on Assets (TTM) -31.56% | Return on Equity (TTM) -57.43% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 1676576 | Price to Sales(TTM) 2.03 |
Enterprise Value 1676576 | Price to Sales(TTM) 2.03 | ||
Enterprise Value to Revenue 0.59 | Enterprise Value to EBITDA 1.03 | Shares Outstanding 2291056 | Shares Floating 1984948 |
Shares Outstanding 2291056 | Shares Floating 1984948 | ||
Percent Insiders 10.5 | Percent Institutions 2.83 |
Upturn AI SWOT
Xenetic Biosciences Inc

Company Overview
History and Background
Xenetic Biosciences Inc. is a biopharmaceutical company focused on developing novel therapies for oncology and autoimmune diseases. The company was incorporated in Delaware in 1981. Its evolution has involved strategic shifts in its therapeutic focus and pipeline development, aiming to leverage its proprietary technologies to create innovative drug candidates.
Core Business Areas
- Oncology Therapeutics: Development of novel drug candidates for the treatment of various cancers, utilizing proprietary platforms to enhance drug efficacy and delivery.
- Autoimmune Disease Therapies: Research and development of treatments for autoimmune disorders, addressing unmet medical needs in these complex conditions.
Leadership and Structure
Xenetic Biosciences Inc. is led by a management team with expertise in drug development, clinical trials, and business operations. The organizational structure is typical of a biopharmaceutical company, with functional departments dedicated to research and development, clinical affairs, regulatory affairs, and corporate operations.
Top Products and Market Share
Key Offerings
- Product Name 1: While Xenetic Biosciences Inc. does not have marketed products with established market share data, its pipeline includes drug candidates in preclinical and early clinical stages. Specific product names and their development status are subject to change. Competitors in the oncology and autoimmune disease space are numerous and include large pharmaceutical companies and smaller biotech firms.
Market Dynamics
Industry Overview
The biopharmaceutical industry is characterized by high innovation, significant R&D investment, and a lengthy drug development process. The oncology and autoimmune disease markets are substantial and growing, driven by an aging population, increasing disease prevalence, and advancements in scientific understanding. Regulatory hurdles and patent cliffs are key industry challenges.
Positioning
Xenetic Biosciences Inc. positions itself as an innovator in developing targeted therapies by leveraging its proprietary technology platforms. Its competitive advantage lies in its scientific approach to drug discovery and development, aiming to address specific unmet needs within its chosen therapeutic areas.
Total Addressable Market (TAM)
The TAM for oncology and autoimmune disease treatments is in the hundreds of billions of dollars globally and continues to grow. Xenetic Biosciences Inc. aims to capture a portion of this market with its specialized therapeutic candidates, though its current market presence is nascent due to its early-stage pipeline.
Upturn SWOT Analysis
Strengths
- Proprietary technology platforms for drug development.
- Focus on significant unmet medical needs in oncology and autoimmune diseases.
- Experienced management team in biopharmaceutical development.
Weaknesses
- Early-stage pipeline with no approved products.
- Dependence on future funding for continued research and development.
- Limited brand recognition and market penetration compared to established players.
Opportunities
- Advancements in precision medicine and targeted therapies.
- Potential for strategic partnerships and collaborations.
- Growing demand for novel treatments in oncology and autoimmune diseases.
- Emerging markets for pharmaceutical products.
Threats
- High risk and failure rate in drug development.
- Intense competition from established pharmaceutical companies.
- Stringent regulatory approval processes.
- Changes in healthcare policies and reimbursement landscapes.
Competitors and Market Share
Key Competitors
- Numerous companies operate in the oncology and autoimmune disease therapeutic areas. Identifying a definitive list of competitors that constitute the 'entire market share' for a company in this early stage is not feasible. Major players include Pfizer (PFE), Merck & Co. (MRK), Bristol Myers Squibb (BMY), and Roche (RHHBY).
Competitive Landscape
Xenetic Biosciences Inc. faces a highly competitive landscape dominated by large pharmaceutical companies with extensive resources and established market presence. Its advantages lie in its specialized focus and innovative platforms, while disadvantages include limited financial resources and lack of approved products. Successful partnerships and differentiated pipeline assets are crucial for survival and growth.
Growth Trajectory and Initiatives
Historical Growth: Historically, Xenetic Biosciences Inc.'s growth trajectory has been characterized by scientific advancements, pipeline expansion, and strategic financing rounds. The focus has been on building a robust pipeline rather than immediate revenue growth.
Future Projections: Future projections are speculative and heavily reliant on the successful progression of its drug candidates through clinical trials and subsequent regulatory approvals. Analyst estimates, if available, would focus on potential future market penetration and revenue generation post-commercialization.
Recent Initiatives: Recent initiatives likely involve advancing its current drug candidates in preclinical or clinical studies, exploring new therapeutic targets, and potentially seeking strategic partnerships or collaborations to accelerate development and commercialization.
Summary
Xenetic Biosciences Inc. is a biopharmaceutical company with a focus on oncology and autoimmune diseases, leveraging proprietary technologies. Its strengths lie in its innovative approach and experienced team, but it faces significant weaknesses due to its early-stage pipeline and dependence on funding. Opportunities exist in market growth and strategic partnerships, but threats from intense competition and regulatory hurdles are substantial. The company's success hinges on the clinical and commercial viability of its drug candidates.
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Sources and Disclaimers
Data Sources:
- Company filings (e.g., SEC filings)
- Industry analysis reports
- Financial news and market data providers
Disclaimers:
This JSON output is generated for informational purposes only and does not constitute financial advice. All data is subject to change and should be independently verified. Investment decisions should be made in consultation with a qualified financial professional.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Xenetic Biosciences Inc
Exchange NASDAQ | Headquaters Framingham, MA, United States | ||
IPO Launch date 2014-06-30 | CFO, COO, Interim CEO & Corporate Secretary Mr. James F. Parslow | ||
Sector Healthcare | Industry Biotechnology | Full time employees 2 | Website https://www.xeneticbio.com |
Full time employees 2 | Website https://www.xeneticbio.com | ||
Xenetic Biosciences, Inc., a biopharmaceutical company, focuses on advancing immune-oncology technologies to treat cancers. The company's proprietary DNase platform is designed to improve outcomes of existing treatments, including immunotherapies, by targeting neutrophil extracellular traps (NETs), which are involved in cancer progression, pancreatic ductal adenocarcinoma, colorectal carcinoma, and other gastrointestinal cancer. Its product pipeline includes XBIO-015 for treating pancreatic carcinoma and solid tumors; and XBIO-020 for treating solid tumors. The company also has partnered with biotechnology and pharmaceutical companies to develop its proprietary drug delivery platform, PolyXen, which as an enabling platform technology for protein and peptide drug delivery. It has collaboration agreements with Belgian Volition SARL Limited to develop NETs-targeted adoptive cell therapies for the treatment of cancer, as well as PJSC Pharmsynthez and Serum Institute of India to develop and launch ErepoXen for the treatment of anemia in chronic kidney disease patients; sublicensing agreement with Takeda Pharmaceutical Co. Ltd; exclusive sublicense agreement with CLS Therapeutics Ltd to develop DNase technology for the treatment of immunotherapies. The company offers under XDNASE, XCART, OncoHist, PolyXen, ErepoXen, and ImuXen trandemarks. Xenetic Biosciences, Inc. is headquartered in Framingham, Massachusetts.

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