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XLO 
Xilio Development Inc (XLO)
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Upturn Advisory Summary
12/12/2025: XLO (1-star) is currently NOT-A-BUY. Pass it for now.
Upturn Star Rating
Not Recommended Performance
These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.
Number of Analysts
1 Analysts rated it
Very few follow this stock; limited insights, higher-risk early investing.
1 Year Target Price $2
1 Year Target Price $2
| 1 | Strong Buy |
| 0 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -16.39% | Avg. Invested days 29 | Today’s Advisory PASS |
Upturn Star Rating | Upturn Advisory Performance  4.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 12/12/2025 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 35.76M USD | Price to earnings Ratio - | 1Y Target Price 2 |
Price to earnings Ratio - | 1Y Target Price 2 | ||
Volume (30-day avg) 1 | Beta -0.05 | 52 Weeks Range 0.61 - 1.70 | Updated Date 12/14/2025 |
52 Weeks Range 0.61 - 1.70 | Updated Date 12/14/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.61 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -183.9% | Operating Margin (TTM) -10.12% |
Management Effectiveness
Return on Assets (TTM) -26.26% | Return on Equity (TTM) -908.28% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -60743027 | Price to Sales(TTM) 1.12 |
Enterprise Value -60743027 | Price to Sales(TTM) 1.12 | ||
Enterprise Value to Revenue 1.95 | Enterprise Value to EBITDA -0.11 | Shares Outstanding 52500328 | Shares Floating 21395984 |
Shares Outstanding 52500328 | Shares Floating 21395984 | ||
Percent Insiders 45.12 | Percent Institutions 30.02 |
About Xilio Development Inc
Exchange NASDAQ | Headquaters Waltham, MA, United States | ||
IPO Launch date 2021-10-22 | President, CEO & Director Dr. Rene Russo BCPS, Pharm.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 64 | Website https://xiliotx.com |
Full time employees 64 | Website https://xiliotx.com | ||
Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of tumor-activated immuno-oncology therapies. The company's checkpoint inhibitor program includes XTX101, an investigational Fc-enhanced, tumor-activated anti-CTLA-4 mAb that is in Phase 2 clinical trial for patients with advanced solid tumors. It also develops cytokine programs, which comprises XTX202, a tumor-activated beta-gamma biased IL-2, currently under Phase 2 clinal trials; and XTX301, an investigational tumor-activated, engineered IL-12 molecule, currently under Phase 1 studies. The company was founded in 2016 and is headquartered in Waltham, Massachusetts.
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