XLO official logo XLO
XLO 1-star rating from Upturn Advisory
Xilio Development Inc (XLO) company logo

Xilio Development Inc (XLO)

Xilio Development Inc (XLO) 1-star rating from Upturn Advisory
$0.68
Last Close (24-hour delay)
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PASS
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Upturn Stock price based on last close icon Stock price based on last close
*as per simulation
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Upturn Advisory Summary

01/09/2026: XLO (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

1 star rating from financial analysts

1 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $2

1 Year Target Price $2

Analysts Price Target For last 52 week
$2 Target price
52w Low $0.62
Current$0.68
52w High $1.7

Analysis of Past Performance

Type Stock
Historic Profit -16.39%
Avg. Invested days 29
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 4.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 01/09/2026
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Key Highlights

Company Size Small-Cap Stock
Market Capitalization 47.63M USD
Price to earnings Ratio -
1Y Target Price 2
Price to earnings Ratio -
1Y Target Price 2
Volume (30-day avg) 1
Beta -0.04
52 Weeks Range 0.61 - 1.70
Updated Date 01/8/2026
52 Weeks Range 0.61 - 1.70
Updated Date 01/8/2026
Dividends yield (FY) -
Basic EPS (TTM) -0.61
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Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -183.9%
Operating Margin (TTM) -10.12%

Management Effectiveness

Return on Assets (TTM) -26.26%
Return on Equity (TTM) -908.28%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -48871137
Price to Sales(TTM) 1.5
Enterprise Value -48871137
Price to Sales(TTM) 1.5
Enterprise Value to Revenue 1.95
Enterprise Value to EBITDA -0.11
Shares Outstanding 67540930
Shares Floating 21283108
Shares Outstanding 67540930
Shares Floating 21283108
Percent Insiders 35.16
Percent Institutions 23.34

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI SWOT

Xilio Development Inc

Xilio Development Inc(XLO) company logo displayed in Upturn AI summary

Company Overview

Company history and background logo History and Background

Xilio Development Inc. is a clinical-stage biotechnology company focused on developing novel immunotherapies for cancer. Founded in 2017, the company has rapidly advanced its pipeline of cytokine-based therapeutics, targeting unmet needs in various solid tumors.

Company business area logo Core Business Areas

  • Oncology Immunotherapy: Xilio Development Inc. is dedicated to pioneering innovative therapies that harness the body's own immune system to fight cancer. Their primary focus is on developing engineered cytokines designed to activate and expand tumor-specific immune cells while minimizing off-target toxicities.

leadership logo Leadership and Structure

Information regarding Xilio Development Inc.'s specific leadership team and organizational structure is proprietary and not publicly disclosed in detail. As a clinical-stage company, it is structured to prioritize research and development, clinical trial management, and regulatory affairs.

Top Products and Market Share

Product Key Offerings logo Key Offerings

  • Product Name 1: Xilio's lead product candidates are engineered cytokines designed to reprogram the tumor microenvironment and enhance anti-tumor immunity. These candidates are in various stages of clinical development for advanced solid tumors. Specific market share data is not applicable at this pre-commercial stage. Competitors in the broader oncology immunotherapy space include companies like Bristol Myers Squibb (Opdivo), Merck (Keytruda), and Pfizer (Inlyta), among many others.

Market Dynamics

industry overview logo Industry Overview

The oncology immunotherapy market is a rapidly growing and highly competitive sector within the pharmaceutical and biotechnology industry. Driven by significant advancements in understanding the immune system's role in cancer, there's a continuous effort to develop more effective and targeted therapies. The market is characterized by substantial investment in R&D, strategic partnerships, and increasing regulatory approvals for novel treatments.

Positioning

Xilio Development Inc. positions itself as a leader in developing next-generation engineered cytokines. Their competitive advantage lies in their proprietary cytokine engineering platform, which aims to overcome the limitations of conventional cytokines by improving efficacy and safety profiles. The company targets specific patient populations with limited treatment options.

Total Addressable Market (TAM)

The total addressable market for oncology immunotherapies is vast and continues to expand with new indications and drug approvals. While Xilio Development Inc.'s current focus is on specific solid tumors, the broader TAM for cancer treatments is in the hundreds of billions of dollars. Xilio is positioned to capture a significant share of its targeted indications as its pipeline matures.

Upturn SWOT Analysis

Strengths

  • Proprietary cytokine engineering platform.
  • Experienced scientific and management team.
  • Focus on a significant unmet need in oncology.
  • Strong preclinical and early-stage clinical data.

Weaknesses

  • Clinical-stage company with no approved products.
  • Dependence on successful clinical trial outcomes.
  • Significant funding requirements for ongoing R&D.
  • Limited brand recognition and market presence.

Opportunities

  • Growing demand for innovative cancer therapies.
  • Potential for strategic partnerships and collaborations.
  • Expansion into new cancer indications.
  • Advancements in biomarker identification for patient selection.

Threats

  • High attrition rate in drug development.
  • Intense competition in the immunotherapy space.
  • Regulatory hurdles and delays.
  • Pricing pressures and reimbursement challenges.

Competitors and Market Share

Key competitor logo Key Competitors

  • Immunocore Ltd. (IMCR)
  • Gritstone Oncology, Inc. (GRTS)
  • Alpine Immune Sciences, Inc. (ALPN)

Competitive Landscape

Xilio Development Inc. operates in a highly competitive landscape. Its advantages lie in its differentiated cytokine engineering technology. However, it faces challenges from established players with approved therapies and a longer track record. Its success depends on demonstrating superior efficacy and safety in clinical trials.

Growth Trajectory and Initiatives

Historical Growth: Xilio Development Inc.'s growth has been marked by the progression of its lead drug candidates through preclinical and early-stage clinical trials, alongside securing significant funding rounds to support these endeavors. Growth is measured in pipeline advancement and successful fundraising.

Future Projections: Future projections are heavily reliant on successful clinical trial outcomes and subsequent regulatory approvals. Analyst estimates would focus on the potential peak sales of its lead candidates, the timing of market entry, and the overall growth of the oncology immunotherapy market.

Recent Initiatives: Recent initiatives likely include the advancement of its clinical programs, potential strategic partnerships or collaborations, and ongoing efforts to secure further funding to support its development activities.

Summary

Xilio Development Inc. is a promising clinical-stage biotechnology company with a strong focus on developing innovative immunotherapies for cancer. Its proprietary technology for engineered cytokines offers a potential advantage in a highly competitive market. However, as a pre-commercial entity, it faces significant risks associated with clinical trial success and the substantial capital required for drug development. The company needs to demonstrate robust clinical efficacy and secure substantial funding to navigate the path to market and establish a strong position.

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Sources and Disclaimers

Data Sources:

  • Company press releases and investor relations materials (where available)
  • Industry research reports
  • Financial news outlets

Disclaimers:

This JSON output is based on publicly available information and general industry knowledge. It is not financial advice and should not be used for investment decisions. The biotechnology sector is highly volatile and speculative. All data is subject to change and may not be exhaustive.

Information icon for Upturn AI Summarization accuracy disclaimer AI Summarization is directionally correct and might not be accurate.

Information icon for Upturn AI Summarization data freshness disclaimer Summarized information shown could be a few years old and not current.

Information icon warning about Upturn AI Fundamental Rating based on potentially old data Fundamental Rating based on AI could be based on old data.

Information icon warning about potential inaccuracies or hallucinations in Upturn AI-generated summaries AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Xilio Development Inc

Exchange NASDAQ
Headquaters Waltham, MA, United States
IPO Launch date 2021-10-22
President, CEO & Director Dr. Rene Russo BCPS, Pharm.D.
Sector Healthcare
Industry Biotechnology
Full time employees 64
Full time employees 64

Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of tumor-activated immuno-oncology therapies. The company's checkpoint inhibitor program includes XTX101, an investigational Fc-enhanced, tumor-activated anti-CTLA-4 mAb that is in Phase 2 clinical trial for patients with advanced solid tumors. It also develops cytokine programs, which comprises XTX202, a tumor-activated beta-gamma biased IL-2, currently under Phase 2 clinal trials; and XTX301, an investigational tumor-activated, engineered IL-12 molecule, currently under Phase 1 studies. The company was founded in 2016 and is headquartered in Waltham, Massachusetts.