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ACHV logo ACHV
Upturn stock ratingUpturn stock rating
ACHV logo

Achieve Life Sciences Inc (ACHV)

Upturn stock ratingUpturn stock rating
$2.26
Last Close (24-hour delay)
Profit since last BUY6.04%
upturn advisory
SELL
SELL since 3 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

06/30/2025: ACHV (1-star) is a SELL. SELL since 3 days. Profits (6.04%). Updated daily EoD!

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

8 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $16.71

1 Year Target Price $16.71

Analysts Price Target For last 52 week
$16.71Target price
Low$1.84
Current$2.26
high$5.31

Analysis of Past Performance

Type Stock
Historic Profit -51.85%
Avg. Invested days 29
Today’s Advisory SELL
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 77.35M USD
Price to earnings Ratio -
1Y Target Price 16.71
Price to earnings Ratio -
1Y Target Price 16.71
Volume (30-day avg) 8
Beta 1.64
52 Weeks Range 1.84 - 5.31
Updated Date 06/30/2025
52 Weeks Range 1.84 - 5.31
Updated Date 06/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.35

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -59.02%
Return on Equity (TTM) -154.55%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 64080053
Price to Sales(TTM) -
Enterprise Value 64080053
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -2.42
Shares Outstanding 34685100
Shares Floating 29417797
Shares Outstanding 34685100
Shares Floating 29417797
Percent Insiders 9.69
Percent Institutions 41.59

Analyst Ratings

Rating 3
Target Price 16.71
Buy 1
Strong Buy 7
Buy 1
Strong Buy 7
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Achieve Life Sciences Inc

stock logo

Company Overview

overview logo History and Background

Achieve Life Sciences Inc. is a pharmaceutical company committed to the global development and commercialization of cytisinicline for smoking cessation and potentially other addictions. Founded in 1994 as New Leaf Bio, Inc., it later changed its name to Achieve Life Sciences.

business area logo Core Business Areas

  • Smoking Cessation: Developing and commercializing cytisinicline, a plant-based compound with a long history of use in Central and Eastern Europe for smoking cessation.

leadership logo Leadership and Structure

The leadership team includes executives with experience in pharmaceutical development, regulatory affairs, and commercialization. The organizational structure is typical of a clinical-stage biotech company focused on a single key asset.

Top Products and Market Share

overview logo Key Offerings

  • Cytisinicline: Cytisinicline is Achieve's primary product, a plant-based smoking cessation aid. It is currently in Phase 3 clinical trials in the US and is already approved and marketed in some Eastern European countries. Competitors include nicotine replacement therapies (NRTs) from Johnson & Johnson (e.g., Nicorette), Pfizer's Chantix (varenicline), and bupropion (Zyban).

Market Dynamics

industry overview logo Industry Overview

The smoking cessation market is a large and growing market, driven by the health risks associated with smoking and increasing public health awareness. The market is competitive with a variety of pharmaceutical and non-pharmaceutical products.

Positioning

Achieve is positioned as a potential competitor to existing smoking cessation therapies, offering a different mechanism of action and a potentially more tolerable side effect profile.

Total Addressable Market (TAM)

The global smoking cessation market is estimated to be in the billions of dollars. Achieve is positioned to capture a share of this market with cytisinicline pending regulatory approval.

Upturn SWOT Analysis

Strengths

  • Novel mechanism of action for smoking cessation
  • Clinical data demonstrating efficacy and safety
  • Experienced management team
  • Established manufacturing and supply chain

Weaknesses

  • Reliance on a single product candidate
  • Limited commercial infrastructure
  • Need for regulatory approval in key markets like the US
  • High cash burn rate

Opportunities

  • Expansion into new markets beyond smoking cessation (e.g., other addictions)
  • Partnerships with larger pharmaceutical companies
  • Positive clinical trial results
  • Increasing public awareness of the dangers of smoking

Threats

  • Competition from existing smoking cessation therapies
  • Regulatory hurdles and delays
  • Patent challenges
  • Adverse clinical trial results

Competitors and Market Share

competitor logo Key Competitors

  • JNJ
  • PFE

Competitive Landscape

Achieve offers cytisinicline as a potential alternative with a unique mechanism of action. JNJ and PFE have already approved therapeutics and thus offer the advantage of market presence.

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been characterized by advancement of the cytisinicline clinical program. R&D expenditure and staffing levels have been increased with the clinical milestones achieved

Future Projections: Future growth depends on the successful completion of clinical trials and regulatory approval of cytisinicline.

Recent Initiatives: Recent initiatives include the completion of Phase 3 clinical trials and preparation for regulatory submissions.

Summary

Achieve Life Sciences is a clinical-stage biotech company focused on cytisinicline for smoking cessation. The company's success hinges on positive clinical trial results and regulatory approval. It faces competition from established players but offers a novel therapeutic approach. Current investors need to consider the risk of the company continuing to have a high cash burn rate.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company SEC Filings
  • Industry Reports
  • Analyst Reports

Disclaimers:

This analysis is for informational purposes only and should not be considered financial advice. Investment decisions should be made based on individual research and consultation with a financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Achieve Life Sciences Inc

Exchange NASDAQ
Headquaters Bothell, WA, United States
IPO Launch date 1995-10-13
CEO & Executive Director Dr. Richard A. B. Stewart
Sector Healthcare
Industry Biotechnology
Full time employees 25
Full time employees 25

Achieve Life Sciences, Inc., a late-stage pharmaceutical company, develops and commercializes cytisinicline for nicotine independence in Canada, the United States, and the United Kingdom. The company offers cytisinicline, a plant-based alkaloid that interacts with nicotine receptors in the brain that reduce the severity of nicotine withdrawal symptoms. It has license and supply agreement with Sopharma AD and University of Bristol. Achieve Life Sciences, Inc., is headquartered in Bothell, Washington.