Adaptive Biotechnologies Corp logo

Adaptive Biotechnologies Corp(ADPT)

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EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL
2-STAR RATING
PASS
LAST CLOSE
$25.8
11/03/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
  • ALL
  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Upturn Advisory & Investor View for ADPT

11/03/2026: ADPT (2-star) is currently NOT-A-BUY. Pass it for now.

Adaptive Biotechnologies is a life sciences company specializing in mapping the human adaptive immune system for diagnostics and drug discovery. Its core strength lies in the clonoSEQ assay, which has a leading position in minimal residual disease monitoring for blood cancers. The primary investment story centers on expanding this diagnostic footprint and leveraging immune data for lucrative biopharma collaborations. However, the company faces risks from high cash burn, evolving reimbursement policies, and competition from large, well-funded diagnostic firms. It may suit growth-oriented investors who can tolerate volatility, while monitoring developments in clinical adoption and path-to-profitability remains crucial for long-term assessment.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company targets high-growth markets in oncology but faces significant execution risks and cash burn.
Momentum investorWeak fitThe stock often lacks consistent positive technical momentum required for short-term trading strategies.
Value investorWeak fitThe lack of consistent profitability makes it an unsuitable candidate for traditional value metrics.
Dividend investorWeak fitThe company does not pay dividends and focuses entirely on growth reinvestment.
Low-risk investorWeak fitHigh volatility associated with clinical-stage and growth-stage biotech makes this unsuitable for risk-averse portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighBiotech stocks often experience sharp price movements based on clinical data or earnings results.
Valuation riskMedium / highInvestors must pay for future growth that is not yet backed by GAAP profitability.
Competition risk (Oncology diagnostics)HighEstablished players with greater scale can impact pricing and market share in MRD testing.
Business qualityMediumWhile the platform technology is robust, the commercial path to consistent margins is still maturing.
Dividend incomeLow / noneThe company does not provide income to shareholders.
Execution riskMedium / highThe company must successfully scale its sales force and diagnostic test adoption to achieve self-sustainment.

Price Behavior

Strong Uptrend
PRICE PATH

Strong Uptrend

The stock has maintained a strong upward price trend across the last three quarters.

Choppy
PRICE STABILITY

Choppy

The stock has experienced frequent reversals and pronounced short-term price swings.

Analysis of Past Performance

Type Stock
Historic Profit -2.73%
Avg. Invested days 31
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 11/03/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
ADPT receives a 3-star rating, supported by solid company fundamentals, and solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
ADPT has solid overall fundamentals (4 stars), with moderate financial health, strong growth momentum, and solid ownership. In FY2025 versus FY2024, strong earnings growth (+62.7%) and strong revenue growth (+54.8%) are partially offset by weak cash generation (FCF margin -17.7%), weak profitability (net margin -21.5%), modest insider ownership of 1.29%.

Financial Health Rating

★★★★★
ADPT's financial health is supported by solid liquidity, including working-capital and asset support (WC/assets 41.0%). Cash strength is soft (2 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is ADPT's strongest growth driver at +62.7% FY2025 versus FY2024 (strong, 5 stars). Revenue growth (+54.8%, strong) and free-cash-flow growth (+50.5%, strong) are also constructive, though not equally high across every growth measure.

Ownership

★★★★★
Institutional ownership is 101.0% and approximately 78.6% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 1.29% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

Viking Global Investors LP 18.79%
BlackRock Inc 9.49%
Vanguard Capital Management, LLC 4.01%
Wellington Management Company LLP 3.70%
Vanguard Portfolio Management, LLC 3.43%

Unit Economics (Per $1K Revenue)

★★★★★
ADPT generates approximately $742 of gross profit, $-206 of operating income, and $-177 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Operating losses and cash burn explain the 1-star rating, with weak cash conversion and weak capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
ADPT has a liquid profile. Weak momentum is the primary drawback, while soft valuation.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 4.00B USD
Price to earnings Ratio -
1Y Target Price 30.21
Price to earnings Ratio -
1Y Target Price 30.21
Volume (30-day avg) 2.2M shares
Beta 2.15
52 Weeks Range 12.00 - 30.74
Updated Date 11/03/2026
52 Weeks Range 12.00 - 30.74
Updated Date 11/03/2026
Dividends yield (FY) -
Basic EPS (TTM) -0.41

How Company Makes Money

Business areaWhat it includesRetail investor read
Clinical DiagnosticsRevenue generated primarily from the clonoSEQ assay for clinical use.The company makes money when doctors use their tests to monitor cancer patients.
Biopharmaceutical CollaborationsFees and milestones from partnerships using the immune medicine platform for drug discovery.The company earns income by helping drug developers find better treatments using immune system data.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Valuation

Trailing PE -
Forward PE -
Enterprise Value 4.32B
Price to Sales(TTM) 12.98
Enterprise Value 4.32B
Price to Sales(TTM) 12.98
Enterprise Value to Revenue 14.02
Enterprise Value to EBITDA -1
Shares Outstanding 159.60M
Shares Floating 125.49M
Shares Outstanding 159.60M
Shares Floating 125.49M
Percent Insiders 1.29
Percent Institutions 101.01

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

Form CRS provides a relationship summary of our automated advisory services, flat subscription fees, and conflicts of interest. Form ADV Part 2A brochure contains complete details on services, billing, and disclosures. If any summary differs from our current regulatory filings, the filed Form ADV controls.