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Adlai Nortye Ltd. American Depositary Shares(ANL)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Advisory Performance History (Simulated)
Upturn Advisory & Investor View for ANL
11/05/2026: ANL (2-star) is currently NOT-A-BUY. Pass it for now.
Adlai Nortye is a clinical-stage biotechnology company focused on advancing novel cancer immunotherapies. Its core strength lies in a specialized oncology pipeline and a global framework for clinical development. The investment story centers on the potential for its lead candidates, like Buparlisib, to achieve regulatory approval in complex cancer markets. However, the company faces significant risks, including the absence of commercial revenue, inherent clinical failure risks, and intense competition from large pharmaceutical firms. The stock best suits investors with a high risk tolerance who are looking for exposure to biotechnology innovation, with progress in clinical trials serving as the most important development to monitor.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Mixed fit | The company represents a high-risk, high-reward investment focused on future clinical success. |
| Momentum investor | Weak fit | Momentum is often erratic in pre-commercial biotech and highly dependent on news flow. |
| Value investor | Weak fit | The company lacks current earnings, making traditional value metrics inapplicable. |
| Dividend investor | Weak fit | There is no history or prospect of dividend payments. |
| Low-risk investor | Weak fit | Clinical-stage biotechnology carries substantial binary risks. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Biotech stocks often experience extreme swings based on clinical data releases. |
| Valuation risk | High | Valuation is highly speculative, based on potential future drug approvals. |
| Competition risk (Oncology drugs) | High | Large pharma companies dominate the space with deeper pockets and more infrastructure. |
| Business quality | Medium | The company focuses on a complex, high-stakes sector, though it remains pre-commercial. |
| Dividend income | Low / none | Investors should not expect income from this equity. |
| Execution risk | High | Successful drug development requires navigating complex clinical and regulatory hurdles. |
Price Behavior

Rolling Over
The price momentum is slowing down and beginning to turn downward.

Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit 198.79% | Avg. Invested days 26 | Today’s Advisory PASS |
Upturn Advisory Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals 
Financial Health Rating 
Growth Momentum Score 
Ownership 
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue) 
Economic Dimensions
Quantitative Style Profile 
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 618.86M USD | Price to earnings Ratio - | 1Y Target Price 29.5 |
Price to earnings Ratio - | 1Y Target Price 29.5 | ||
Volume (30-day avg) 285.5K shares | Beta 1.41 | 52 Weeks Range 0.88 - 17.25 | Updated Date 11/04/2026 |
52 Weeks Range 0.88 - 17.25 | Updated Date 11/04/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.66 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Oncology Research | Clinical-stage development of Buparlisib and other candidates. | The company spends money on research and hopes to generate revenue through future drug sales or partnerships. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 410.82M | Price to Sales(TTM) 34.27 |
Enterprise Value 410.82M | Price to Sales(TTM) 34.27 | ||
Enterprise Value to Revenue 22.75 | Enterprise Value to EBITDA - | Shares Outstanding 58.73M | Shares Floating 49.57M |
Shares Outstanding 58.73M | Shares Floating 49.57M | ||
Percent Insiders 0.94 | Percent Institutions 41.3 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

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