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BBIO 
BridgeBio Pharma Inc (BBIO)
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Upturn Advisory Summary
11/05/2025: BBIO (5-star) is a STRONG-BUY. BUY since 133 days. Simulated Profits (72.05%). Updated daily EoD!
Upturn Star Rating
Outstanding Performance
These Stocks/ETFs, based on Upturn Advisory, have historically outperformed the market, making them a top-tier choice for investors.
Number of Analysts
19 Analysts rated it
Moderately tracked stock, growing coverage, gaining market and investor attention.
1 Year Target Price $83.11
1 Year Target Price $83.11
| 10 | Strong Buy |
| 6 | Buy |
| 3 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 97.9% | Avg. Invested days 39 | Today’s Advisory Strong Buy |
Upturn Star Rating | Upturn Advisory Performance  3.0 | Stock Returns Performance  4.0 |
| Profits based on simulation | Last Close 11/05/2025 |
Key Highlights
Company Size Large-Cap Stock | Market Capitalization 12.09B USD | Price to earnings Ratio - | 1Y Target Price 83.11 |
Price to earnings Ratio - | 1Y Target Price 83.11 | ||
Volume (30-day avg) 19 | Beta 1.27 | 52 Weeks Range 21.72 - 69.48 | Updated Date 11/8/2025 |
52 Weeks Range 21.72 - 69.48 | Updated Date 11/8/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -4.15 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date 2025-10-30 | When - | Estimate -0.8577 | Actual -0.7166 |
Profitability
Profit Margin -225.32% | Operating Margin (TTM) -112.97% |
Management Effectiveness
Return on Assets (TTM) -43.48% | Return on Equity (TTM) -1789.67% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 11286931893 | Price to Sales(TTM) 34.17 |
Enterprise Value 11286931893 | Price to Sales(TTM) 34.17 | ||
Enterprise Value to Revenue 47.86 | Enterprise Value to EBITDA -9.4 | Shares Outstanding 192708813 | Shares Floating 153174600 |
Shares Outstanding 192708813 | Shares Floating 153174600 | ||
Percent Insiders 4.73 | Percent Institutions 100.74 |
Upturn AI SWOT
BridgeBio Pharma Inc
Company Overview
History and Background
BridgeBio Pharma Inc. was founded in 2015 with the goal of discovering, developing, and delivering transformative medicines for patients with genetic diseases and cancers with clear genetic drivers. It has grown through internal development and strategic acquisitions.
Core Business Areas
- Drug Discovery and Development: Focuses on identifying and developing therapies for genetic diseases and genetically driven cancers.
Leadership and Structure
The leadership team includes Neil Kumar, Ph.D. as CEO. The company has a board of directors and operates through various functional departments like R&D, commercial, and operations.
Top Products and Market Share
Key Offerings
- Truseltiq (infigratinib): A kinase inhibitor approved for previously treated, unresectable biliary tract cancer with FGFR2 fusions or rearrangements. Its main competitors are other targeted therapies and chemotherapies used in biliary tract cancer treatment. Market share is still growing in the FGFR2-altered biliary tract cancer space.
Market Dynamics
Industry Overview
The pharmaceutical industry is highly competitive and heavily regulated. It is characterized by high R&D costs and long development timelines.
Positioning
BridgeBio Pharma Inc. positions itself as a leader in developing precision medicines for genetic diseases and cancers with clear genetic drivers. Their competitive advantage lies in their targeted approach and deep scientific understanding of disease mechanisms.
Total Addressable Market (TAM)
The TAM for genetic diseases and genetically driven cancers is very large, likely in the tens or hundreds of billions of dollars, given the broad range of diseases and increasing use of precision medicine. BridgeBio is positioned to capture a share of this TAM with its targeted therapies.
Upturn SWOT Analysis
Strengths
- Strong focus on genetic diseases and cancers
- Deep understanding of disease mechanisms
- Experienced leadership team
- Strategic partnerships
- Commercial product (Truseltiq)
Weaknesses
- High R&D expenses
- Dependence on clinical trial outcomes
- Competition from larger pharmaceutical companies
- Limited number of marketed products
Opportunities
- Expanding pipeline through internal development and acquisitions
- Partnerships with leading research institutions
- Accelerated approval pathways for rare diseases
- Increasing prevalence of genetic testing
Threats
- Clinical trial failures
- Regulatory hurdles
- Patent expirations
- Competition from new therapies
- Pricing pressures
Competitors and Market Share
Key Competitors
- ROSE (Roche Holding AG)
- MRK (Merck & Co., Inc.)
- PFE (Pfizer Inc.)
Competitive Landscape
BridgeBio competes with both large pharmaceutical companies and smaller biotech firms. Its strengths are its focus on precision medicine and its deep scientific expertise. Its weaknesses include its relatively small size and limited resources.
Growth Trajectory and Initiatives
Historical Growth: Historical growth analysis requires actual financial data and is not possible at this time.
Future Projections: Future growth projections require analyst estimates and are not possible at this time.
Recent Initiatives: Recent initiatives include advancing clinical trials, strategic partnerships, and commercialization efforts.
Summary
BridgeBio Pharma has a focused approach on genetic diseases and cancers which gives them a strong position in a niche market. While they have a commercial product, they are still dependent on clinical trial successes and face significant competition. Managing R&D costs and expanding their product pipeline will be critical. Their strategic partnerships and focus on areas with unmet medical needs may drive future growth, but regulatory hurdles and market access challenges could pose significant threats.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company website
- SEC filings
- Analyst reports
- Industry publications
Disclaimers:
This analysis is based on publicly available information and is not financial advice. Market share estimates may not be precise and are subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About BridgeBio Pharma Inc
Exchange NASDAQ | Headquaters Palo Alto, CA, United States | ||
IPO Launch date 2019-06-27 | Co-Founder, CEO & Director Dr. Neil Kumar Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 725 | Website https://bridgebio.com |
Full time employees 725 | Website https://bridgebio.com | ||
BridgeBio Pharma, Inc., a commercial-stage biopharmaceutical company, discovers, creates, tests, and delivers transformative medicines to treat patients who suffer from genetic diseases and cancers. The company offers Attruby, a next-generation oral small molecule near-complete TTR stabilizer for the treatment of cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM); low-dose infigratinib, an oral FGFR1-3 selective tyrosine kinase inhibitor, which is in Phase 3 double-blinded, placebo-controlled pivotal study for the treatment option for children with achondroplasia; low-dose infigratinib, a treatment option for children living with hypochondroplasia, a skeletal dysplasia closely related to achondroplasia which is in Phase 2/3. The company also develops Encaleret, a small molecule antagonist of the calcium sensing receptor, or CaSR, which is in phase 3 clinical trial for treating autosomal dominant hypocalcemia type 1, or ADH1; and BBP-418, a glycosylation substrate pro-drug that is in Phase 3 clinical trial for treating limb-girdle muscular dystrophy type 2I/R9 (LGMD2I/R9). In addition, it engages in developing products for mendelian, oncology, and gene therapy diseases. In addition, it engages in developing products for mendelian, oncology, and gene therapy diseases. The company has license and collaboration agreements with the Alexion Pharma International Operations Unlimited Company, Leland Stanford Junior University and Leidos Biomedical Research, Inc., and Novartis International Pharmaceutical Ltd. BridgeBio Pharma, Inc. was founded in 2015 and is headquartered in Palo Alto, California.
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