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Upturn AI Summary - About
Bicycle Therapeutics Ltd(BCYC)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for BCYC
11/09/2026: BCYC (1-star) is currently NOT-A-BUY. Pass it for now.
Bicycle Therapeutics is a clinical-stage biotechnology company focused on developing a proprietary class of medicines called Bicycle molecules, which are designed for high target specificity in oncology. The company's core strength lies in its unique technology platform, which offers the precision of antibodies with the favorable properties of small molecules. Its primary growth story revolves around advancing its pipeline of drug conjugates through clinical trials and establishing high-value partnerships. However, investors face significant execution risks, as the company has no commercialized products and remains heavily dependent on clinical trial outcomes. This stock is best suited for growth-oriented investors with a high risk tolerance.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Strong fit | The company offers high-growth potential linked to its proprietary technology platform and clinical trial outcomes. |
| Momentum investor | Mixed fit | This is a conditional fit depending on positive news flow and clinical trial momentum. |
| Value investor | Weak fit | The lack of commercial products and current operating losses make this unsuitable for traditional value metrics. |
| Dividend investor | Weak fit | The company does not pay dividends and requires all capital for development. |
| Low-risk investor | Weak fit | Biotech clinical development is inherently high-risk and volatile. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Clinical-stage biotech stocks are highly sensitive to study outcomes and sector sentiment. |
| Valuation risk | Medium / high | Valuation is speculative and heavily dependent on long-term pipeline success probabilities. |
| Competition risk (ADC and targeted oncology) | High | The company faces competition from deep-pocketed firms in the oncology space. |
| Business quality | Medium | The company possesses a strong scientific platform but lacks commercial validation. |
| Dividend income | Low / none | The company is in an early growth phase and does not provide income. |
| Execution risk | High | Success relies entirely on the successful navigation of complex clinical trials. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Moderately Choppy
The stock has experienced noticeable price swings while retaining some directional structure.
Analysis of Past Performance
Type Stock | Historic Profit -49.81% | Avg. Invested days 21 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  1.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 11/09/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 253.04M USD | Price to earnings Ratio - | 1Y Target Price 9.17 |
Price to earnings Ratio - | 1Y Target Price 9.17 | ||
Volume (30-day avg) 462.2K shares | Beta 1.6 | 52 Weeks Range 3.33 - 7.83 | Updated Date 11/08/2026 |
52 Weeks Range 3.33 - 7.83 | Updated Date 11/08/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.03 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Drug Development and Partnerships | License fees, research support, and milestone payments from biopharma partners. | Revenue is sporadic, coming from collaborative agreements rather than consistent product sales. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -203.41M | Price to Sales(TTM) 3.03 |
Enterprise Value -203.41M | Price to Sales(TTM) 3.03 | ||
Enterprise Value to Revenue 21.22 | Enterprise Value to EBITDA -2.14 | Shares Outstanding 50.66M | Shares Floating 7.76M |
Shares Outstanding 50.66M | Shares Floating 7.76M | ||
Percent Insiders 4.58 | Percent Institutions 71.58 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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