BRTX official logo BRTX
BRTX 1-star rating from Upturn Advisory
BioRestorative Therapies Inc (BRTX) company logo

BioRestorative Therapies Inc (BRTX)

BioRestorative Therapies Inc (BRTX) 1-star rating from Upturn Advisory
$1.18
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PASS
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Upturn Advisory Summary

01/07/2026: BRTX (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

1 star rating from financial analysts

2 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $13

1 Year Target Price $13

Analysts Price Target For last 52 week
$13 Target price
52w Low $0.98
Current$1.18
52w High $2.55

Analysis of Past Performance

Type Stock
Historic Profit -65.57%
Avg. Invested days 29
Today’s Advisory PASS
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 01/07/2026

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 10.47M USD
Price to earnings Ratio -
1Y Target Price 13
Price to earnings Ratio -
1Y Target Price 13
Volume (30-day avg) 2
Beta 0.18
52 Weeks Range 0.98 - 2.55
Updated Date 01/7/2026
52 Weeks Range 0.98 - 2.55
Updated Date 01/7/2026
Dividends yield (FY) -
Basic EPS (TTM) -1.46

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -31432.3%

Management Effectiveness

Return on Assets (TTM) -89.73%
Return on Equity (TTM) -207.73%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -2646262
Price to Sales(TTM) 27.32
Enterprise Value -2646262
Price to Sales(TTM) 27.32
Enterprise Value to Revenue 1.27
Enterprise Value to EBITDA 0.13
Shares Outstanding 8876242
Shares Floating 5993949
Shares Outstanding 8876242
Shares Floating 5993949
Percent Insiders 22.35
Percent Institutions 9.37

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI SWOT

BioRestorative Therapies Inc

BioRestorative Therapies Inc(BRTX) company logo displayed in Upturn AI summary

Company Overview

Company history and background logo History and Background

BioRestorative Therapies Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing regenerative medicine products. Founded in 2004, the company has primarily concentrated on its proprietary cell therapy platform. A significant milestone was its focus on developing treatments for disc-related conditions and neurodegenerative diseases.

Company business area logo Core Business Areas

  • ThermoStemu00ae Platform: The company's core technology revolves around its ThermoStemu00ae platform, which involves the use of autologous adipose-derived stem cells. These cells are processed and intended for therapeutic applications, primarily in spinal disc repair and potential treatments for conditions like Alzheimer's and Parkinson's disease.

leadership logo Leadership and Structure

BioRestorative Therapies Inc. is led by a management team with experience in the biotechnology and pharmaceutical sectors. The organizational structure is typical of a clinical-stage company, with a focus on research and development, clinical trials, and regulatory affairs.

Top Products and Market Share

Product Key Offerings logo Key Offerings

  • ThermoStemu00ae for Disc Disease: This is the company's lead product candidate, intended for the treatment of degenerative disc disease. It involves harvesting a patient's own fat tissue, isolating stem cells, and re-injecting them into the damaged intervertebral discs. The company aims to promote tissue regeneration and alleviate pain. Competitors in this space include companies developing surgical interventions, other cell-based therapies, and non-surgical pain management solutions.
  • ThermoStemu00ae for Neurodegenerative Diseases: BioRestorative is also exploring the potential of ThermoStemu00ae for treating neurodegenerative conditions such as Alzheimer's and Parkinson's disease. This application is in earlier stages of development, focusing on the neuroprotective and regenerative properties of stem cells. Competitors include pharmaceutical companies developing drug therapies and other research institutions investigating cell-based treatments for these complex diseases.

Market Dynamics

industry overview logo Industry Overview

The regenerative medicine and cell therapy market is a rapidly growing sector within the broader biopharmaceutical industry. It is characterized by significant investment in research and development, a focus on addressing unmet medical needs, and a complex regulatory pathway.

Positioning

BioRestorative Therapies Inc. is positioned as a developer of autologous stem cell therapies. Its competitive advantage lies in its proprietary ThermoStemu00ae platform and its focus on specific, often underserved, therapeutic areas like degenerative disc disease and neurodegenerative disorders. However, as a clinical-stage company, it faces the challenges inherent in bringing novel therapies through rigorous clinical trials and regulatory approval.

Total Addressable Market (TAM)

The Total Addressable Market (TAM) for treatments of degenerative disc disease and neurodegenerative diseases is substantial, encompassing millions of patients globally. For degenerative disc disease alone, the market is valued in the billions of dollars. BioRestorative Therapies Inc. is positioned to capture a portion of this market if its ThermoStemu00ae therapy proves safe and effective and receives regulatory approval, but it faces competition from established and emerging therapies.

Upturn SWOT Analysis

Strengths

  • Proprietary ThermoStemu00ae cell therapy platform.
  • Focus on addressing significant unmet medical needs in pain management and neurodegenerative diseases.
  • Autologous (patient's own cells) approach may reduce immune rejection concerns.
  • Clinical-stage company with ongoing research and development activities.

Weaknesses

  • Clinical-stage status, meaning no approved products to generate revenue.
  • Reliance on successful completion of clinical trials and regulatory approvals.
  • Limited financial resources compared to larger pharmaceutical companies.
  • Potential challenges in scaling manufacturing for widespread commercialization.
  • Competition from established and emerging treatments.

Opportunities

  • Significant unmet needs in degenerative disc disease and neurodegenerative disorders.
  • Growing interest and investment in regenerative medicine and cell therapies.
  • Potential for partnerships or collaborations with larger pharmaceutical companies.
  • Expansion of ThermoStemu00ae platform to other therapeutic areas.

Threats

  • Failure to demonstrate efficacy or safety in clinical trials.
  • Regulatory hurdles and lengthy approval processes.
  • Intense competition from established and emerging therapies.
  • Changes in healthcare reimbursement policies.
  • Economic downturns impacting healthcare spending and investment.

Competitors and Market Share

Key competitor logo Key Competitors

  • Companies developing cell therapies for orthopedic conditions (e.g., disc repair).
  • Biopharmaceutical companies with drug candidates for Alzheimer's and Parkinson's.
  • Companies offering surgical or other non-cell-based interventions for degenerative disc disease.

Competitive Landscape

BioRestorative Therapies Inc. operates in a competitive landscape where larger, more established pharmaceutical companies and numerous smaller biotech firms are also developing treatments for similar conditions. The company's advantage lies in its specific autologous stem cell approach and targeted indications, but it faces significant challenges in navigating the complex clinical and regulatory pathways and competing for market share against well-funded entities.

Growth Trajectory and Initiatives

Historical Growth: Historically, BioRestorative Therapies Inc.'s growth has been characterized by progress in its research and development pipeline and the advancement of its ThermoStemu00ae platform through various stages of preclinical and clinical investigation. Growth is measured by scientific milestones rather than financial revenue growth.

Future Projections: Future growth projections for BioRestorative Therapies Inc. are contingent upon the successful completion of its clinical trials, securing regulatory approvals, and effective commercialization of its therapies. Analyst projections, if available, would be based on these key de-risking events. Significant growth is anticipated only upon product launch.

Recent Initiatives: Recent initiatives likely involve the progression of clinical trials for its lead indications, efforts to optimize manufacturing processes for its cell therapies, and potential strategic partnerships or collaborations to advance its pipeline.

Summary

BioRestorative Therapies Inc. is a clinical-stage company focused on regenerative medicine with its ThermoStemu00ae cell therapy platform. Its strengths lie in its proprietary technology and focus on significant unmet medical needs. However, it faces substantial risks due to its clinical-stage status, reliance on trial success, and intense competition. The company's future success hinges on navigating regulatory hurdles and demonstrating clinical efficacy and safety to secure market entry and generate revenue.

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Sources and Disclaimers

Data Sources:

  • Company filings (e.g., SEC filings)
  • Industry reports and market analysis
  • Financial news and data providers

Disclaimers:

This JSON output provides a structured overview of BioRestorative Therapies Inc. based on publicly available information. It is intended for informational purposes only and does not constitute financial advice or an endorsement of the company. Investing in clinical-stage biopharmaceutical companies carries significant risk. All data is subject to change, and users should conduct their own due diligence.

Information icon for Upturn AI Summarization accuracy disclaimer AI Summarization is directionally correct and might not be accurate.

Information icon for Upturn AI Summarization data freshness disclaimer Summarized information shown could be a few years old and not current.

Information icon warning about Upturn AI Fundamental Rating based on potentially old data Fundamental Rating based on AI could be based on old data.

Information icon warning about potential inaccuracies or hallucinations in Upturn AI-generated summaries AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About BioRestorative Therapies Inc

Exchange NASDAQ
Headquaters Melville, NY, United States
IPO Launch date 2007-07-27
Chairman of the Board, President & CEO Mr. Lance Alstodt
Sector Healthcare
Industry Biotechnology
Full time employees 11
Full time employees 11

BioRestorative Therapies, Inc. develops therapeutic products and medical therapies using cell and tissue protocols primarily involving adult stem cells. It develops programs relate to the treatment of disc/spine disease and metabolic disorders. The company's products pipeline comprises BRTX-100, a lead cell therapy candidate formulated from autologous cultured mesenchymal stem cells collected from the patient's bone marrow, as well as used for the non-surgical treatment of painful lumbosacral disc disorders or as a complimentary therapeutic to a surgical procedure; and ThermoStem, a cell-based therapy candidate to target obesity and metabolic disorders using brown adipose derived stem cells to generate brown adipose tissue. It also operates a commercial biocosmeceutical platform. In addition, the company provides investigational curved needle device to deliver cells and/or other therapeutic products or material to the spine and discs, and other parts of the body. BioRestorative Therapies, Inc. has a research and development agreement with Rohto Pharmaceutical Co., Ltd.; a research agreement with Pfizer, Inc.; and a research collaboration agreement with the University of Pennsylvania. The company was formerly known as Stem Cell Assurance, Inc. and changed its name to BioRestorative Therapies, Inc. in August 2011. BioRestorative Therapies, Inc. is headquartered in Melville, New York.