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Cardio Diagnostics Holdings Inc (CDIO)


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Upturn Advisory Summary
10/29/2025: CDIO (1-star) is a SELL. SELL since 3 days. Simulated Profits (-3.69%). Updated daily EoD!
1 Year Target Price $60
1 Year Target Price $60
| 1 | Strong Buy | 
| 0 | Buy | 
| 0 | Hold | 
| 0 | Sell | 
| 0 | Strong Sell | 
Analysis of Past Performance
|  Type  Stock |  Historic Profit  -0.35% |  Avg. Invested days  50 |  Today’s Advisory  SELL  | 
|  Upturn Star Rating   |  Upturn Advisory Performance   2.0 |  Stock Returns Performance   1.0 | 
|  Profits based on simulation |  Last Close 10/29/2025 | 
Key Highlights
|  Company Size  Small-Cap Stock  |  Market Capitalization  7.48M  USD  |  Price to earnings Ratio  -  |  1Y Target Price  60  | 
|  Price to earnings Ratio  -  |  1Y Target Price  60  | ||
|  Volume (30-day avg)  1  |  Beta  2.86  |  52 Weeks Range  3.22 - 53.10  |  Updated Date  10/29/2025  | 
|  52 Weeks Range  3.22 - 53.10  |  Updated Date  10/29/2025  | ||
|  Dividends yield (FY)  -  |  Basic EPS (TTM)  -3.75  | 
Earnings Date
|  Report Date  -  |  When  -  |  Estimate  -  |  Actual  -  | 
Profitability
|  Profit Margin  -  |  Operating Margin (TTM)  -22457.51%  | 
Management Effectiveness
|  Return on Assets (TTM)  -54.15%  |  Return on Equity (TTM)  -97.67%  | 
Valuation
|  Trailing PE  -  |  Forward PE  -  |  Enterprise Value  73231  |  Price to Sales(TTM)  383.23  | 
|  Enterprise Value  73231  |  Price to Sales(TTM)  383.23  | ||
|  Enterprise Value to Revenue  3.75  |  Enterprise Value to EBITDA  -22.48  |  Shares Outstanding  1763129  |  Shares Floating  1634685  | 
|  Shares Outstanding  1763129  |  Shares Floating  1634685  | ||
|  Percent Insiders  7.04  |  Percent Institutions  4.81  | 
 Upturn AI SWOT
 Upturn AI SWOT 
Cardio Diagnostics Holdings Inc

Company Overview
 History and Background
 History and Background 
Cardio Diagnostics Holdings, Inc. (CDIO) focuses on developing integrated genetic-clinical solutions for cardiovascular disease. Founded relatively recently, it aims to transform cardiovascular disease detection and prevention through personalized diagnostics.
 Core Business Areas
 Core Business Areas 
- Integrated Genetic-Clinical Solutions: Develops and commercializes diagnostic tests and solutions that combine genetic information with traditional clinical risk factors to improve cardiovascular disease risk assessment.
- Proprietary AI Platform: Utilizes artificial intelligence to analyze complex data sets and generate personalized insights for healthcare providers and patients.
 Leadership and Structure
 Leadership and Structure 
Details regarding the exact organizational structure and leadership team can be found in their official investor relations releases and SEC filings.
Top Products and Market Share
 Key Offerings
 Key Offerings 
- AWAREu2122: A clinical test integrating genetics and clinical data, used to assess individual risk for cardiovascular disease. Market share information is not readily available for this specific product. Competitors are companies offering similar cardiovascular risk assessment tools.
- PrecisionCHDu2122: A test designed to identify individuals at risk for coronary heart disease (CHD). Market share and user data are not readily available publicly. Competitors are those offering similar CHD risk assessment products.
Market Dynamics
 Industry Overview
 Industry Overview 
The cardiovascular diagnostics market is growing, driven by increased prevalence of heart disease, advancements in diagnostic technologies, and a focus on personalized medicine.
Positioning
Cardio Diagnostics aims to differentiate itself through its integrated genetic-clinical approach and AI-powered analysis. They are positioning themselves as innovators in precision cardiovascular medicine.
Total Addressable Market (TAM)
The cardiovascular diagnostics market is estimated to be billions of dollars. Cardio Diagnostics is positioned to capture a share of this TAM by offering more precise and personalized risk assessment tools.
Upturn SWOT Analysis
Strengths
- Innovative technology platform
- Focus on personalized medicine
- Potential for improved risk prediction
Weaknesses
- Limited commercial traction
- Reliance on partnerships
- Need for extensive clinical validation
Opportunities
- Expanding market for cardiovascular diagnostics
- Partnerships with healthcare providers and payers
- Development of new diagnostic tests
Threats
- Competition from established players
- Regulatory hurdles
- Reimbursement challenges
Competitors and Market Share
 Key Competitors
 Key Competitors 
- MDT
- ILMN
- DGX
Competitive Landscape
Cardio Diagnostics faces significant competition from larger, more established players in the cardiovascular diagnostics market. Its success depends on its ability to demonstrate the clinical and economic value of its integrated genetic-clinical solutions.
Growth Trajectory and Initiatives
Historical Growth: Historical growth can be assessed by analyzing revenue trends from their SEC filings.
Future Projections: Future growth projections are typically provided by analyst estimates which are based on market conditions and Cardio Diagnostics' ability to gain traction in the market.
Recent Initiatives: Monitor recent press releases and company announcements for strategic initiatives such as partnerships, product launches, and clinical trial results.
Summary
Cardio Diagnostics is an emerging player in the cardiovascular diagnostics market with innovative technology. The company is still in its early stages of commercialization and faces significant competition and financial hurdles. Successful partnerships and clinical validation are crucial for future growth. The company's early-stage nature makes it a higher-risk, higher-reward investment at this stage.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company SEC Filings
- Company Investor Relations
- Market Research Reports
Disclaimers:
This analysis is based on publicly available information and should not be considered financial advice. Market share data is estimated and may not be precise. Investors should conduct their own due diligence before making investment decisions.
 AI Summarization is directionally correct and might not be accurate.
 AI Summarization is directionally correct and might not be accurate. 
 Summarized information shown could be a few years old and not current.
 Summarized information shown could be a few years old and not current. 
 Fundamental Rating based on AI could be based on old data.
 Fundamental Rating based on AI could be based on old data. 
 AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
 AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action. 
About Cardio Diagnostics Holdings Inc
|  Exchange  NASDAQ  |  Headquaters  Chicago, IL, United States  | ||
|  IPO Launch date  2022-01-14  |  Co-Founder, CEO & Director  Dr. Meeshanthini V. Dogan Ph.D.  | ||
|  Sector  Healthcare  |  Industry  Biotechnology  |  Full time employees  13  |  Website  https://cdio.ai  | 
|  Full time employees  13  |  Website  https://cdio.ai  | ||
Cardio Diagnostics Holdings, Inc. develops and commercializes epigenetics-based clinical tests for cardiovascular disease. The company offers Epi+Gen CHD, a three-year symptomatic coronary heart disease (CHD) risk assessment clinical blood test targeting CHD events, including heart attacks; PrecisionCHD, an integrated epigenetic-genetic clinical blood test for the detection of coronary heart disease; and Actionable Clinical Intelligence, a platform that offers new epigenetic and genetic insights to clinicians prescribing to help improve chronic care management. It also provides CardioInnovate360, a research-use-only solution to support the discovery, development and validation of novel biopharmaceuticals for the assessment and management of cardiovascular diseases; and HeartRisk, a SaaS cardiovascular disease risk intelligence platform. It serves telemedicine providers; provider organizations, including concierge practices, longevity clinics, and risk-bearing provider organizations; and employer organizations. Cardio Diagnostics Holdings, Inc. was founded in 2017 and is headquartered in Chicago, Illinois.

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