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Upturn stock rating
CNTA logo

Centessa Pharmaceuticals PLC ADR (CNTA)

Upturn stock rating
$23.98
Last Close (24-hour delay)
Today's Top Performer Top performer
Profit since last BUY5.59%
upturn advisory
Strong Buy
BUY since 36 days
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  • SELL Advisory (Loss)
  • Profit
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Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • 1Y
  • 1M
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Upturn Advisory Summary

10/29/2025: CNTA (4-star) is a STRONG-BUY. BUY since 36 days. Simulated Profits (5.59%). Updated daily EoD!

Upturn Star Rating

rating

Above Average Performance

These Stocks/ETFs, based on Upturn Advisory, frequently surpass the market, reflecting reliable and trustworthy advice.

Number of Analysts

rating

11 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $33.23

1 Year Target Price $33.23

Analysts Price Target For last 52 week
$33.23 Target price
52w Low $9.6
Current$23.98
52w High $25.31

Analysis of Past Performance

Type Stock
Historic Profit 149.51%
Avg. Invested days 44
Today’s Advisory Strong Buy
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 4.0
Stock Returns Performance Upturn Returns Performance 5.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/29/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 3.35B USD
Price to earnings Ratio -
1Y Target Price 33.23
Price to earnings Ratio -
1Y Target Price 33.23
Volume (30-day avg) 11
Beta 1.57
52 Weeks Range 9.60 - 25.31
Updated Date 10/29/2025
52 Weeks Range 9.60 - 25.31
Updated Date 10/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.85

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -1376.1%

Management Effectiveness

Return on Assets (TTM) -28.96%
Return on Equity (TTM) -72.92%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 2957809699
Price to Sales(TTM) 223.46
Enterprise Value 2957809699
Price to Sales(TTM) 223.46
Enterprise Value to Revenue 197.19
Enterprise Value to EBITDA 1.12
Shares Outstanding 134073436
Shares Floating 85057529
Shares Outstanding 134073436
Shares Floating 85057529
Percent Insiders 0.48
Percent Institutions 93.46

ai summary icon Upturn AI SWOT

Centessa Pharmaceuticals PLC ADR

stock logo

Company Overview

overview logo History and Background

Centessa Pharmaceuticals PLC ADR (CNTA) was created to accelerate the identification and development of high-impact medicines for patients. It achieves this through a unique asset-centric model.

business area logo Core Business Areas

  • Drug Development: Focuses on acquiring and developing innovative drug candidates across various therapeutic areas.
  • Clinical Trials: Conducts clinical trials to evaluate the safety and efficacy of its drug candidates.
  • Regulatory Approvals: Seeks regulatory approvals from agencies like the FDA for its products.

leadership logo Leadership and Structure

The leadership team includes experienced executives from the pharmaceutical industry. The company is structured around an asset-centric model, with individual teams focused on specific drug candidates.

Top Products and Market Share

overview logo Key Offerings

  • Imbruvica (ibrutinib): This is a BTK inhibitor co-developed with AbbVie (ABBV). It has a share of the Bruton's tyrosine kinase (BTK) inhibitor market, competing with others like Calquence (acalabrutinib) by AstraZeneca (AZN).
  • Other Pipeline Assets: Centessa is developing a number of other assets across a number of theraputic areas, however none of these have achieved material market share yet.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry is characterized by high research and development costs, lengthy regulatory approval processes, and intense competition. Innovation and intellectual property are key drivers of success.

Positioning

Centessa aims to differentiate itself through its asset-centric approach, focusing on acquiring promising drug candidates and accelerating their development. Its competitive advantage lies in its experienced management team and streamlined structure.

Total Addressable Market (TAM)

TAM varies significantly depending on the specific therapeutic area. Centessa's positioning depends on the success of its pipeline assets.

Upturn SWOT Analysis

Strengths

  • Experienced Management Team
  • Asset-Centric Model
  • Strong Pipeline
  • Innovative Drug Candidates

Weaknesses

  • High R&D Costs
  • Regulatory Risk
  • Commercialization Challenges
  • Dependence on Pipeline Success

Opportunities

  • Strategic Partnerships
  • Expansion into New Therapeutic Areas
  • Accelerated Regulatory Pathways
  • Acquisition of Promising Assets

Threats

  • Competition from Larger Pharmaceutical Companies
  • Generic Drug Entry
  • Patent Expiry
  • Unfavorable Regulatory Changes

Competitors and Market Share

competitor logo Key Competitors

  • ABBV
  • AZN
  • BMY
  • MRK
  • PFE

Competitive Landscape

Centessa faces intense competition from larger pharmaceutical companies with more established product portfolios and greater financial resources. Its success depends on the unique value proposition of its pipeline assets.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is measured by pipeline progress, not revenue. Focus on clinical trial milestones.

Future Projections: Future growth depends on successful clinical trial outcomes and regulatory approvals.

Recent Initiatives: Recent initiatives include advancing key pipeline assets through clinical trials.

Summary

Centessa Pharmaceuticals PLC ADR is a development-stage pharmaceutical company with an asset-centric model. Its future success hinges on the successful development and commercialization of its pipeline assets. Key strengths include an experienced management team and a focus on innovative drug candidates. Investors should closely monitor clinical trial progress and regulatory milestones.

Similar Stocks

Sources and Disclaimers

Data Sources:

  • Company Filings
  • Analyst Reports
  • Industry Publications

Disclaimers:

This analysis is for informational purposes only and does not constitute investment advice. Investment decisions should be based on individual due diligence and consultation with a financial advisor.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Centessa Pharmaceuticals PLC ADR

Exchange NASDAQ
Headquaters -
IPO Launch date 2021-05-28
CEO & Director Dr. Saurabh Saha M.D., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 98
Full time employees 98

Centessa Pharmaceuticals plc, a clinical-stage pharmaceutical company, discovers, develops, and delivers medicines. Its lead clinical-stage program includes ORX750, an orally administered OX2R agonist in a Phase 2a study for the treatment of idiopathic hypersomnia and narcolepsy type 1 and 2. The company also develops ORX142 for the treatment of neurological and neurodegenerative disorders, as well as other potential symptoms, including excessive daytime sleepiness, impaired attention, cognitive deficits, and fatigue; and ORX489 for the treatment of neuropsychiatric disorders. In addition, it offers LockBody, which is designed to selectively drive potent effector function activity, such as CD3, into the tumor microenvironment. Centessa Pharmaceuticals plc was incorporated in 2020 and is headquartered in Altrincham, the United Kingdom.