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CNTA 
Centessa Pharmaceuticals PLC ADR (CNTA)
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Upturn Advisory Summary
11/12/2025: CNTA (5-star) is a SELL. SELL since 4 days. Simulated Profits (-2.60%). Updated daily EoD!
Upturn Star Rating
Outstanding Performance
These Stocks/ETFs, based on Upturn Advisory, have historically outperformed the market, making them a top-tier choice for investors.
Number of Analysts
11 Analysts rated it
Moderately tracked stock, growing coverage, gaining market and investor attention.
1 Year Target Price $33.92
1 Year Target Price $33.92
| 7 | Strong Buy |
| 4 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 130.15% | Avg. Invested days 45 | Today’s Advisory SELL |
Upturn Star Rating | Upturn Advisory Performance  4.0 | Stock Returns Performance  5.0 |
| Profits based on simulation | Last Close 11/12/2025 |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 3.03B USD | Price to earnings Ratio - | 1Y Target Price 33.92 |
Price to earnings Ratio - | 1Y Target Price 33.92 | ||
Volume (30-day avg) 11 | Beta 1.57 | 52 Weeks Range 9.60 - 27.18 | Updated Date 11/12/2025 |
52 Weeks Range 9.60 - 27.18 | Updated Date 11/12/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.89 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
Report Date 2025-11-17 | When - | Estimate -0.3884 | Actual -0.41 |
Profitability
Profit Margin - | Operating Margin (TTM) -1425.33% |
Management Effectiveness
Return on Assets (TTM) -25.26% | Return on Equity (TTM) -60.62% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 2872920699 | Price to Sales(TTM) 202.03 |
Enterprise Value 2872920699 | Price to Sales(TTM) 202.03 | ||
Enterprise Value to Revenue 191.53 | Enterprise Value to EBITDA 1.12 | Shares Outstanding 134447836 | Shares Floating 85180401 |
Shares Outstanding 134447836 | Shares Floating 85180401 | ||
Percent Insiders 0.48 | Percent Institutions 94.29 |
Upturn AI SWOT
Centessa Pharmaceuticals PLC ADR
Company Overview
History and Background
Centessa Pharmaceuticals PLC ADR (CNTA) was created to accelerate the identification and development of high-impact medicines for patients. It achieves this through a unique asset-centric model.
Core Business Areas
- Drug Development: Focuses on acquiring and developing innovative drug candidates across various therapeutic areas.
- Clinical Trials: Conducts clinical trials to evaluate the safety and efficacy of its drug candidates.
- Regulatory Approvals: Seeks regulatory approvals from agencies like the FDA for its products.
Leadership and Structure
The leadership team includes experienced executives from the pharmaceutical industry. The company is structured around an asset-centric model, with individual teams focused on specific drug candidates.
Top Products and Market Share
Key Offerings
- Imbruvica (ibrutinib): This is a BTK inhibitor co-developed with AbbVie (ABBV). It has a share of the Bruton's tyrosine kinase (BTK) inhibitor market, competing with others like Calquence (acalabrutinib) by AstraZeneca (AZN).
- Other Pipeline Assets: Centessa is developing a number of other assets across a number of theraputic areas, however none of these have achieved material market share yet.
Market Dynamics
Industry Overview
The pharmaceutical industry is characterized by high research and development costs, lengthy regulatory approval processes, and intense competition. Innovation and intellectual property are key drivers of success.
Positioning
Centessa aims to differentiate itself through its asset-centric approach, focusing on acquiring promising drug candidates and accelerating their development. Its competitive advantage lies in its experienced management team and streamlined structure.
Total Addressable Market (TAM)
TAM varies significantly depending on the specific therapeutic area. Centessa's positioning depends on the success of its pipeline assets.
Upturn SWOT Analysis
Strengths
- Experienced Management Team
- Asset-Centric Model
- Strong Pipeline
- Innovative Drug Candidates
Weaknesses
- High R&D Costs
- Regulatory Risk
- Commercialization Challenges
- Dependence on Pipeline Success
Opportunities
- Strategic Partnerships
- Expansion into New Therapeutic Areas
- Accelerated Regulatory Pathways
- Acquisition of Promising Assets
Threats
- Competition from Larger Pharmaceutical Companies
- Generic Drug Entry
- Patent Expiry
- Unfavorable Regulatory Changes
Competitors and Market Share
Key Competitors
- ABBV
- AZN
- BMY
- MRK
- PFE
Competitive Landscape
Centessa faces intense competition from larger pharmaceutical companies with more established product portfolios and greater financial resources. Its success depends on the unique value proposition of its pipeline assets.
Growth Trajectory and Initiatives
Historical Growth: Historical growth is measured by pipeline progress, not revenue. Focus on clinical trial milestones.
Future Projections: Future growth depends on successful clinical trial outcomes and regulatory approvals.
Recent Initiatives: Recent initiatives include advancing key pipeline assets through clinical trials.
Summary
Centessa Pharmaceuticals PLC ADR is a development-stage pharmaceutical company with an asset-centric model. Its future success hinges on the successful development and commercialization of its pipeline assets. Key strengths include an experienced management team and a focus on innovative drug candidates. Investors should closely monitor clinical trial progress and regulatory milestones.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company Filings
- Analyst Reports
- Industry Publications
Disclaimers:
This analysis is for informational purposes only and does not constitute investment advice. Investment decisions should be based on individual due diligence and consultation with a financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Centessa Pharmaceuticals PLC ADR
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2021-05-28 | CEO & Director Dr. Saurabh Saha M.D., Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 77 | Website https://centessa.com |
Full time employees 77 | Website https://centessa.com | ||
Centessa Pharmaceuticals plc, a clinical-stage pharmaceutical company, discovers, develops, and delivers medicines. Its lead clinical-stage program includes ORX750, an orally administered OX2R agonist in a Phase 2a study for the treatment of idiopathic hypersomnia and narcolepsy type 1 and 2. The company also develops ORX142 for the treatment of neurological and neurodegenerative disorders, as well as other potential symptoms, including excessive daytime sleepiness, impaired attention, cognitive deficits, and fatigue; and ORX489 for the treatment of neuropsychiatric disorders. In addition, it offers LockBody, which is designed to selectively drive potent effector function activity, such as CD3, into the tumor microenvironment. Centessa Pharmaceuticals plc was incorporated in 2020 and is headquartered in Altrincham, the United Kingdom.
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