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Upturn AI Summary - About
CytomX Therapeutics Inc(CTMX)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for CTMX
10/27/2026: CTMX (3-star) is currently NOT-A-BUY. Pass it for now.
CytomX Therapeutics is a clinical-stage biotechnology company focused on its proprietary Probody platform, designed to deliver safer cancer treatments by activating therapies only within the tumor microenvironment. The company's strengths lie in its innovative drug-masking technology and its history of securing strategic partnerships with large pharmaceutical firms. The primary investment story rests on the potential for clinical success in its oncology pipeline, specifically for candidates like CX-904. Key risks include the inherent volatility of clinical-stage biotech, the lack of commercialized products, and intense competition. This stock is best suited for risk-tolerant investors looking to monitor clinical trial milestones and partnership-driven R&D outcomes.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Weak fit | The company is in an early-to-mid clinical stage with high risk and no commercial revenue. |
| Momentum investor | Mixed fit | Fits only during positive clinical trial readouts or major partnership announcements. |
| Value investor | Weak fit | Lack of earnings and product revenue makes traditional valuation difficult. |
| Dividend investor | Weak fit | The company does not pay dividends and reinvests all capital into R&D. |
| Low-risk investor | Weak fit | Biotechnology R&D carries significant binary risk. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Biotech stocks often react violently to clinical trial results. |
| Valuation risk | High | Valuation is highly speculative and based on long-term pipeline success probabilities. |
| Competition risk (Oncology R&D) | High | The market is crowded with well-funded competitors. |
| Business quality | Medium | While the platform is innovative, the lack of commercialized products limits business maturity. |
| Dividend income | Low / none | No income is generated for shareholders. |
| Execution risk | High | Success depends entirely on the ability to conduct and pass clinical trials. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit 112.22% | Avg. Invested days 29 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  3.0 | Stock Returns Performance  5.0 |
| Profits based on simulation | Last Close 10/27/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 484.83M USD | Price to earnings Ratio - | 1Y Target Price 12.25 |
Price to earnings Ratio - | 1Y Target Price 12.25 | ||
Volume (30-day avg) 3.8M shares | Beta 2.2 | 52 Weeks Range 2.16 - 8.21 | Updated Date 10/27/2026 |
52 Weeks Range 2.16 - 8.21 | Updated Date 10/27/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.51 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Collaboration and Licensing | Milestone payments and royalties from partnerships with pharmaceutical companies. | The company makes money by partnering with large drug companies to develop its technology, receiving payments when milestones are met. |
Valuation
Trailing PE - | Forward PE 14.2 | Enterprise Value 178.77M | Price to Sales(TTM) 26.49 |
Enterprise Value 178.77M | Price to Sales(TTM) 26.49 | ||
Enterprise Value to Revenue 9.77 | Enterprise Value to EBITDA 8.72 | Shares Outstanding 217.90M | Shares Floating 179.66M |
Shares Outstanding 217.90M | Shares Floating 179.66M | ||
Percent Insiders 0.57 | Percent Institutions 104.59 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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