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Guardant Health Inc(GH)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL RECENCY
5-STAR RATING
STRONG BUY
BUY for 32 days
PROFIT SINCE LAST BUY
+9.93%
LAST CLOSE
$179.38
09/18/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Advisory Performance History (Simulated)Advisory Performance History info

Upturn Advisory & Investor View for GH

09/18/2026: GH (5-star) is a STRONG-BUY. BUY for 32 days. Simulated Profits (9.93%). Updated daily EoD!

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Analysis of Past Performance

Type Stock
Historic Profit 92.94%
Avg. Invested days 29
Today’s Advisory Strong Buy
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 4.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/18/2026

Upturn Scorecard

Upturn Star Rating

GH receives a 3-star rating, supported by solid company fundamentals, and solid analyst coverage. The rating is constrained by weak unit economics, and limited analyst upside.

Company Fundamentals

GH has solid overall fundamentals (4 stars), with moderate financial health, solid growth momentum, and solid ownership. In FY2025 versus FY2024, moderate earnings growth (+4.6%) and solid revenue growth (+32.9%) are partially offset by soft cash generation (FCF margin -23.7%), soft profitability (net margin -42.4%), modest insider ownership of 3.97%.

Financial Health Rating

GH's financial health is supported by solid liquidity, including working-capital and asset support (WC/assets 57.8%). Cash strength is soft (2 stars), which helps explain the 3-star overall score.

Growth Momentum Score

Revenue growth is GH's strongest growth driver at +32.9% FY2025 versus FY2024 (solid, 4 stars). Earnings growth (+4.6%, moderate) and free-cash-flow growth (+15.2%, solid) are also constructive, though not equally high across every growth measure.

Ownership

Institutional ownership is 100.9% and approximately 96.5% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 3.97% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

BlackRock Inc 8.61%
T. Rowe Price Associates, Inc. 5.23%
Vanguard Portfolio Management, LLC 4.35%
Vanguard Capital Management, LLC 4.19%
Amvescap Plc. 3.69%

Unit Economics (Per $1K Revenue)

GH generates approximately $645 of gross profit, $-445 of operating income, and $-237 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

Effective Tax Rate: 0.30%

Quantitative Style Profile

GH has a large-cap, liquid profile. Valuation that is moderately attractive rather than deeply discounted is the primary drawback, while elevated volatility.

Style Classification

Quality Focused

High VolatilityLarge / Mega Cap StabilityShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 24.57B USD
Price to earnings Ratio -
1Y Target Price 195.81
Price to earnings Ratio -
1Y Target Price 195.81
Volume (30-day avg) 2.0M shares
Beta 1.58
52 Weeks Range 55.38 - 183.51
Updated Date 09/17/2026
52 Weeks Range 55.38 - 183.51
Updated Date 09/17/2026
Dividends yield (FY) -
Basic EPS (TTM) -3.68

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

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Valuation

Trailing PE -
Forward PE -
Enterprise Value 24.11B
Price to Sales(TTM) 20.77
Enterprise Value 24.11B
Price to Sales(TTM) 20.77
Enterprise Value to Revenue 20.38
Enterprise Value to EBITDA -5.4
Shares Outstanding 134.20M
Shares Floating 129.46M
Shares Outstanding 134.20M
Shares Floating 129.46M
Percent Insiders 3.97
Percent Institutions 100.86

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Guardant Health Inc

Exchange NASDAQ
Headquarters Palo Alto, CA, United States
IPO Launch date 2018-10-04
Co-Founder, Co-CEO & Chairman Dr. Helmy Eltoukhy Ph.D.
Sector Healthcare
Industry Diagnostics & Research
Full time employees 2490
Full time employees 2490

Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; and Guardant360 Tissue test, a molecular profiling test for tumor tissue that provides genomic, transcriptomic, and epigenomic insights. It also provides Shield blood test for colorectal cancer screening in adults. In addition, the company offers GuardantINFINITY test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantOMNI test covers 500 genes, including genes associated with homologous recombination repair deficiency and biomarkers for immuno-oncology applications; GuardantINFORM, which provides longitudinal biological insight into tumor evolution alongside longitudinal clinical outcomes; and GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies. Further, it provides Smart Platform, which delivers multiomic insights leveraging genomic, epigenomic, and RNA-based data that are scalable from research to the clinic. Additionally, the company offers development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. It has a strategic collaboration with Nuvalent, Inc. for oncology drug development. The company was incorporated in 2011 and is headquartered in Palo Alto, California.