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Guardant Health Inc (GH)

Upturn stock ratingUpturn stock rating
$64.47
Last Close (24-hour delay)
Profit since last BUY10.07%
upturn advisory
Strong Buy
BUY since 12 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

08/28/2025: GH (3-star) is a STRONG-BUY. BUY since 12 days. Profits (10.07%). Updated daily EoD!

Upturn Star Rating

rating

Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Number of Analysts

rating

24 Analysts rated it

Well-followed company, solid analyst reports, reliable data for confident investing.

1 Year Target Price $61.33

1 Year Target Price $61.33

Analysts Price Target For last 52 week
$61.33 Target price
52w Low $20.14
Current$64.47
52w High $67.51

Analysis of Past Performance

Type Stock
Historic Profit 17.38%
Avg. Invested days 24
Today’s Advisory Strong Buy
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 2.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/28/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 8.04B USD
Price to earnings Ratio -
1Y Target Price 61.33
Price to earnings Ratio -
1Y Target Price 61.33
Volume (30-day avg) 24
Beta 1.44
52 Weeks Range 20.14 - 67.51
Updated Date 08/28/2025
52 Weeks Range 20.14 - 67.51
Updated Date 08/28/2025
Dividends yield (FY) -
Basic EPS (TTM) -3.35

Analyzing Revenue: Products, Geography and Growth

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date 2025-07-30
When -
Estimate -0.72
Actual -0.44

Profitability

Profit Margin -49.93%
Operating Margin (TTM) -45.75%

Management Effectiveness

Return on Assets (TTM) -19.57%
Return on Equity (TTM) -4584.47%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 8744794600
Price to Sales(TTM) 9.7
Enterprise Value 8744794600
Price to Sales(TTM) 9.7
Enterprise Value to Revenue 10.4
Enterprise Value to EBITDA -5.4
Shares Outstanding 124706000
Shares Floating 119555505
Shares Outstanding 124706000
Shares Floating 119555505
Percent Insiders 4.5
Percent Institutions 98.98

ai summary icon Upturn AI SWOT

Guardant Health Inc

stock logo

Company Overview

overview logo History and Background

Guardant Health was founded in 2012. It focuses on developing non-invasive cancer tests using liquid biopsies. The company's initial focus was on advanced-stage cancer, but has expanded to early-stage detection and recurrence monitoring.

business area logo Core Business Areas

  • Precision Oncology Testing: Offers comprehensive genomic profiling services for advanced cancer patients to help physicians select appropriate therapies. This includes Guardant360 and Guardant360 CDx.
  • Early Cancer Detection: Developing blood tests for early detection of cancer in high-risk individuals. This includes the Shield test.
  • Development Partnerships: Collaborates with pharmaceutical companies to develop companion diagnostics and support clinical trials.

leadership logo Leadership and Structure

Helmy Eltoukhy (CEO), AmirAli Talasaz (President and Co-CEO). Operates with a typical corporate structure, with departments focused on research, development, commercial operations, and finance.

Top Products and Market Share

overview logo Key Offerings

  • Guardant360 CDx: A comprehensive liquid biopsy test for advanced-stage cancer patients. It identifies genomic alterations to help guide treatment decisions. Competitors include Foundation Medicine (FMI) and Roche.
  • Guardant Reveal: A liquid biopsy test for detecting minimal residual disease (MRD) and monitoring recurrence. Competitors include Natera (NTRA) and Adaptive Biotechnologies (ADPT).
  • Shield: A blood test designed for early cancer detection. It is intended for screening average-risk individuals. Competitors include Exact Sciences (EXAS) and Grail (acquired by Illumina).

Market Dynamics

industry overview logo Industry Overview

The liquid biopsy market is rapidly growing due to its potential for non-invasive cancer diagnostics and personalized medicine. Key drivers include advances in genomics, increasing cancer incidence, and demand for less invasive diagnostic methods.

Positioning

Guardant Health is a leader in the liquid biopsy market, particularly in advanced-stage cancer testing. It aims to expand its reach into early cancer detection and recurrence monitoring. Competitive advantages include its established brand, comprehensive testing platform, and extensive clinical data.

Total Addressable Market (TAM)

The total addressable market for liquid biopsy is estimated to be in the tens of billions of dollars. Guardant Health is positioned to capture a significant portion of this market by expanding its product offerings and targeting different stages of cancer care.

Upturn SWOT Analysis

Strengths

  • Leading market position in liquid biopsy
  • Comprehensive testing platform
  • Strong brand recognition
  • Extensive clinical data
  • Established relationships with pharmaceutical companies

Weaknesses

  • High operating expenses
  • Dependence on reimbursement from payers
  • Competition from larger diagnostic companies
  • Regulatory uncertainty

Opportunities

  • Expanding into early cancer detection
  • Increasing adoption of liquid biopsy in clinical practice
  • Developing new biomarkers and tests
  • Partnering with pharmaceutical companies to develop companion diagnostics
  • International expansion

Threats

  • Increasing competition
  • Reimbursement challenges
  • Regulatory changes
  • Technological advancements by competitors
  • Economic downturn

Competitors and Market Share

competitor logo Key Competitors

  • FMI
  • NTRA
  • EXAS
  • ILMN

Competitive Landscape

Guardant Health faces competition from both large diagnostic companies and smaller, specialized liquid biopsy firms. Guardant Health's advantages include its comprehensive testing platform and established brand. However, it needs to continue to innovate and expand its product offerings to maintain its market leadership.

Major Acquisitions

Lunit, Inc.

  • Year: 2024
  • Acquisition Price (USD millions): 0
  • Strategic Rationale: Through an alliance with Lunit, GH is seeking to expand the capabilities of data and analytics as well as the combined insights across their diagnostic offerings.

Growth Trajectory and Initiatives

Historical Growth: Data unavailable, needs updated yearly financial data.

Future Projections: Analysts project continued revenue growth for Guardant Health, driven by increasing adoption of its products and expansion into new markets.

Recent Initiatives: Focus on Shield test rollout, expanding partnerships with pharmaceutical companies, and investing in research and development.

Summary

Guardant Health is a leader in the liquid biopsy market with strong offerings for advanced-stage cancer. It aims to expand into early detection, which is a promising but competitive market. High operating expenses and reimbursement challenges remain concerns. Its success hinges on expanding its product offerings and maintaining its market leadership amidst increasing competition.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company filings
  • Analyst reports
  • Industry publications

Disclaimers:

This analysis is based on publicly available information and should not be considered financial advice. Market conditions and company performance can change, impacting the accuracy of this analysis.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Guardant Health Inc

Exchange NASDAQ
Headquaters Palo Alto, CA, United States
IPO Launch date 2018-10-04
Co-Founder, Co-CEO & Chairman Dr. Helmy Eltoukhy Ph.D.
Sector Healthcare
Industry Diagnostics & Research
Full time employees 1999
Full time employees 1999

Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company provides precision oncology testing services comprising Guardant360, a panel of genetic tests; Guardant360 LDT that measures 730+ genes and supports all guideline-recommended biomarkers; Guardant360 CDx Test, a liquid biopsy test; Guardant360 Response Test, a blood-only liquid biopsy; Guardant360 TissueNext Test, a tissue-based test with AI-powered PD-L1 detection; GuardantINFINITY Test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies; GuardantOMNI blood test for advanced stage cancer; and GuardantINFORM, an in-silico research platform for tumor evolution and treatment resistance across various biomarker-driven cancers. It also offers Shield Test; Guardant Reveal Test for adjuvant treatment and surveillance settings in early-stage cancer patients; and Smart Liquid Biopsy Platform. In addition, the company provides development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. The company was incorporated in 2011 and is headquartered in Palo Alto, California.