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Guardant Health Inc (GH)

Upturn stock ratingUpturn stock rating
$50.86
Last Close (24-hour delay)
Profit since last BUY1.54%
upturn advisory
Strong Buy
BUY since 13 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
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Upturn Advisory Summary

06/27/2025: GH (3-star) is a STRONG-BUY. BUY since 13 days. Profits (1.54%). Updated daily EoD!

Upturn Star Rating

ratingratingratingratingrating

Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Number of Analysts

rating

24 Analysts rated it

These Stocks/ETFs, based on Upturn Advisory, have historically outperformed the market, making them a top-tier choice for investors.

Year Target Price $59.43

Year Target Price $59.43

Analyst’s Price TargetsFor last 52 week
$59.43Target price
Low$20.14
Current$50.86
high$53.42

Analysis of Past Performance

Type Stock
Historic Profit 18.83%
Avg. Invested days 24
Today’s Advisory Strong Buy
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 2.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/27/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 6.30B USD
Price to earnings Ratio -
1Y Target Price 59.66
Price to earnings Ratio -
1Y Target Price 59.66
Volume (30-day avg) -
Beta 1.38
52 Weeks Range 20.14 - 53.42
Updated Date 06/29/2025
52 Weeks Range 20.14 - 53.42
Updated Date 06/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -3.39

Earnings Date

Report Date 2025-06-12
When After Market
Estimate -0.85
Actual -0.49

Profitability

Profit Margin -53.82%
Operating Margin (TTM) -54.33%

Management Effectiveness

Return on Assets (TTM) -18.64%
Return on Equity (TTM) -4584.47%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 6905040327
Price to Sales(TTM) 8.14
Enterprise Value 6905040327
Price to Sales(TTM) 8.14
Enterprise Value to Revenue 8.92
Enterprise Value to EBITDA -5.4
Shares Outstanding 123888000
Shares Floating 118676075
Shares Outstanding 123888000
Shares Floating 118676075
Percent Insiders 4.6
Percent Institutions 97.67

Analyst Ratings

Rating 4.5
Target Price 59.43
Buy 6
Strong Buy 15
Buy 6
Strong Buy 15
Hold 3
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Guardant Health Inc

stock logo

Company Overview

overview logo History and Background

Guardant Health was founded in 2012. The company focuses on developing non-invasive cancer tests to improve outcomes across all stages of the disease.

business area logo Core Business Areas

  • Precision Oncology Testing: Offers a range of liquid biopsy tests for advanced cancer patients, enabling oncologists to make informed treatment decisions based on genomic insights.
  • Early Cancer Detection: Develops blood-based tests for the early detection of cancer, aiming to improve survival rates through earlier diagnosis.
  • Biopharmaceutical Services: Partners with pharmaceutical companies to accelerate drug development by leveraging its liquid biopsy platform for clinical trials and biomarker discovery.

leadership logo Leadership and Structure

Helmy Eltoukhy serves as co-CEO, and AmirAli Talasaz as co-CEO. The organizational structure includes departments focused on research and development, commercial operations, and clinical affairs.

Top Products and Market Share

overview logo Key Offerings

  • Guardant360 CDx: A comprehensive genomic profiling test for advanced cancer patients, used to identify actionable mutations. Competitors: Foundation Medicine, Roche.
  • Guardant Reveal: A liquid biopsy test for detecting residual or recurrent disease in early-stage cancer. Competitors: Exact Sciences.
  • Guardant Shield: Blood test for early cancer screening. Competitors: Grail, Exact Sciences.

Market Dynamics

industry overview logo Industry Overview

The oncology diagnostics market is growing rapidly, driven by advancements in genomics and increasing demand for personalized medicine.

Positioning

Guardant Health is a leader in the liquid biopsy market, with a strong focus on innovation and clinical validation. They hold a competitive advantage through their comprehensive product portfolio and established relationships with oncologists.

Total Addressable Market (TAM)

The total addressable market for cancer diagnostics and screening is estimated to be substantial (greater than $50 billion). Guardant Health is targeting a significant portion of this TAM through its various tests and services.

Upturn SWOT Analysis

Strengths

  • Strong brand recognition
  • Comprehensive product portfolio
  • Established relationships with oncologists
  • Robust intellectual property

Weaknesses

  • High operating expenses due to research and development
  • Reliance on reimbursement approvals
  • Competition from larger diagnostic companies
  • Cash burn

Opportunities

  • Expansion into new geographic markets
  • Development of new liquid biopsy tests
  • Partnerships with pharmaceutical companies
  • Increase in adoption of early cancer screening

Threats

  • Regulatory changes
  • Reimbursement challenges
  • Competition from new entrants
  • Economic downturn

Competitors and Market Share

competitor logo Key Competitors

  • Foundation Medicine (RHHBY)
  • Exact Sciences (EXAS)
  • Illumina (ILMN)

Competitive Landscape

Guardant Health faces competition from larger diagnostic companies with established market positions. However, Guardant Health has a strong focus on innovation and a comprehensive product portfolio, giving it a competitive edge in the liquid biopsy market.

Major Acquisitions

CellSearch Liquid Biopsy Business from Menarini

  • Year: 2022
  • Acquisition Price (USD millions): 70
  • Strategic Rationale: Expanded access to a circulating tumor cell (CTC) platform

Growth Trajectory and Initiatives

Historical Growth: Guardant Health has experienced significant revenue growth in recent years, driven by increased adoption of its liquid biopsy tests. However, they have not yet turned profitable.

Future Projections: Analysts project continued revenue growth for Guardant Health, driven by increased adoption of its products and expansion into new markets. Profitability is anticipated in the coming years but is dependent on successful commercialization and reimbursement.

Recent Initiatives: Recent initiatives include expanding collaborations with pharmaceutical companies and advancing the development of new liquid biopsy tests for early cancer detection.

Summary

Guardant Health is a leading player in the rapidly growing liquid biopsy market, boasting a strong brand and comprehensive product portfolio. They have demonstrated strong revenue growth, however, high operating expenses and reliance on reimbursements have impacted profitability. To ensure the long-term success, Guardant Health must continue to develop new cancer tests and expand into new markets, while closely monitoring regulatory changes and managing cash burn. The recent acquisition will improve their future growth with additional market exposure.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company Website
  • Analyst Reports
  • SEC Filings
  • Industry Reports

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Market data is subject to change. Consult with a qualified financial advisor before making any investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Guardant Health Inc

Exchange NASDAQ
Headquaters Palo Alto, CA, United States
IPO Launch date 2018-10-04
Co-Founder, Co-CEO & Chairman Dr. Helmy Eltoukhy Ph.D.
Sector Healthcare
Industry Diagnostics & Research
Full time employees 1999
Full time employees 1999

Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company provides precision oncology testing services comprising Guardant360, a panel of genetic tests; Guardant360 LDT that measures 730+ genes and supports all guideline-recommended biomarkers; Guardant360 CDx Test, a liquid biopsy test; Guardant360 Response Test, a blood-only liquid biopsy; Guardant360 TissueNext Test, a tissue-based test with AI-powered PD-L1 detection; GuardantINFINITY Test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies; GuardantOMNI blood test for advanced stage cancer; and GuardantINFORM, an in-silico research platform for tumor evolution and treatment resistance across various biomarker-driven cancers. It also offers Shield Test; Guardant Reveal Test for adjuvant treatment and surveillance settings in early-stage cancer patients; and Smart Liquid Biopsy Platform. In addition, the company provides development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. The company was incorporated in 2011 and is headquartered in Palo Alto, California.