Upturn unsubscribed user
$1.14/ day, billed weekly
Cancel anytime
(Ad-Free, Unlimited access)​
NO CREDIT CARD REQUIRED
INVA logo INVA
Upturn stock ratingUpturn stock rating
INVA logo

Innoviva Inc (INVA)

Upturn stock ratingUpturn stock rating
$20.88
Last Close (24-hour delay)
Profit since last BUY1.75%
upturn advisory
Consider higher Upturn Star rating
BUY since 10 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

09/02/2025: INVA (2-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Number of Analysts

rating

1 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $41

1 Year Target Price $41

Analysts Price Target For last 52 week
$41 Target price
52w Low $16.67
Current$20.88
52w High $22

Analysis of Past Performance

Type Stock
Historic Profit 27.19%
Avg. Invested days 46
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 3.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/02/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.29B USD
Price to earnings Ratio 35.84
1Y Target Price 41
Price to earnings Ratio 35.84
1Y Target Price 41
Volume (30-day avg) 1
Beta 0.39
52 Weeks Range 16.67 - 22.00
Updated Date 09/1/2025
52 Weeks Range 16.67 - 22.00
Updated Date 09/1/2025
Dividends yield (FY) -
Basic EPS (TTM) 0.57

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date 2025-08-06
When After Market
Estimate 0.5
Actual 0.77

Profitability

Profit Margin 10.44%
Operating Margin (TTM) 48.61%

Management Effectiveness

Return on Assets (TTM) 8.83%
Return on Equity (TTM) 5.6%

Valuation

Trailing PE 35.84
Forward PE 15.24
Enterprise Value 1240694316
Price to Sales(TTM) 3.48
Enterprise Value 1240694316
Price to Sales(TTM) 3.48
Enterprise Value to Revenue 3.35
Enterprise Value to EBITDA 11.12
Shares Outstanding 63021000
Shares Floating 57648473
Shares Outstanding 63021000
Shares Floating 57648473
Percent Insiders 0.98
Percent Institutions 128.45

ai summary icon Upturn AI SWOT

Innoviva Inc

stock logo

Company Overview

overview logo History and Background

Innoviva Inc. was founded in 1996 as Theravance, Inc. and later separated its drug discovery operations from its commercialized respiratory assets. It rebranded as Innoviva in 2014. The company focuses on royalty management and strategic investments in respiratory medicines.

business area logo Core Business Areas

  • Royalty Management: Innoviva receives royalties from GlaxoSmithKline (GSK) related to sales of respiratory medicines developed through a collaboration with Theravance Biopharma. This constitutes their primary revenue stream.
  • Strategic Investments: Innoviva invests in and acquires companies within the biopharmaceutical sector, aiming to generate additional revenue streams and enhance shareholder value.

leadership logo Leadership and Structure

Innoviva operates under a board of directors. Key leadership roles include the Chief Executive Officer and Chief Financial Officer. The structure is relatively lean, focusing on managing royalty revenues and strategic investments.

Top Products and Market Share

overview logo Key Offerings

  • TRELEGY ELLIPTA (GSK Royalty): TRELEGY ELLIPTA is a once-daily triple combination inhaler (ICS/LABA/LAMA) for COPD and asthma. Innoviva receives royalties on global sales generated by GSK. Competitors include AstraZeneca's Symbicort and Breztri Aerosphere.
  • ANORO ELLIPTA (GSK Royalty): ANORO ELLIPTA is a once-daily LAMA/LABA inhaler for COPD. Innoviva receives royalties on global sales generated by GSK. Competitors include Boehringer Ingelheim's Stiolto Respimat.
  • RELVAR/BREO ELLIPTA (GSK Royalty): RELVAR/BREO ELLIPTA is a once-daily ICS/LABA inhaler for asthma and COPD. Innoviva receives royalties on global sales generated by GSK. Competitors include AstraZeneca's Symbicort.

Market Dynamics

industry overview logo Industry Overview

The respiratory drug market is characterized by high demand driven by increasing prevalence of asthma and COPD. Major players compete through innovative drug delivery systems and combination therapies.

Positioning

Innoviva is primarily a royalty-collecting entity. Its competitive advantage lies in its existing collaboration agreements with GSK and its ability to generate significant cash flow from these partnerships.

Total Addressable Market (TAM)

The global respiratory disease market is estimated to reach hundreds of billions USD. Innoviva, through its royalty streams tied to GSK's products, is well-positioned to capture a portion of this TAM. Exact figures on TAM and Innoviva positioning within TAM are complex due to the structure of the Royalty agreements.

Upturn SWOT Analysis

Strengths

  • Consistent royalty revenue stream from GSK
  • High profit margins due to royalty-based business model
  • Strong cash flow generation
  • Experienced management team

Weaknesses

  • Dependence on GSK's success and product performance
  • Limited control over marketing and sales of partnered products
  • Vulnerability to patent expirations
  • Requires continuous investment and acquisitions to generate revenue

Opportunities

  • Expanding respiratory drug market
  • Potential for new collaborations and partnerships
  • Strategic acquisitions of complementary businesses
  • Geographic expansion of partnered products

Threats

  • Generic competition
  • Regulatory changes impacting pricing and market access
  • Adverse clinical trial results for partnered products
  • Changes in GSK's strategic priorities

Competitors and Market Share

competitor logo Key Competitors

  • AZN
  • LLY
  • MRK

Competitive Landscape

Innoviva's advantage lies in its royalty-based model, providing a steady revenue stream. However, it lacks direct control over product marketing and is dependent on GSK's success. Competitors like AstraZeneca (AZN), Lilly (LLY) and Merck (MRK) have broader product portfolios and direct control over commercialization activities.

Major Acquisitions

Entasis Therapeutics

  • Year: 2022
  • Acquisition Price (USD millions): 113
  • Strategic Rationale: Acquisition of Entasis Therapeutics aimed to expand Innoviva's portfolio with a clinical-stage antibiotic program and diversify its revenue streams beyond respiratory products.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is closely tied to the performance of GSK's respiratory products and strategic decisions made by Innoviva regarding investments and acquisitions.

Future Projections: Future projections depend on analyst estimates and company guidance. Key factors include the growth of the respiratory drug market and the success of GSK's partnered products.

Recent Initiatives: Recent initiatives may include strategic acquisitions, investments in new technologies, or efforts to diversify revenue streams.

Summary

Innoviva is a royalty management company heavily reliant on GSK's respiratory drug sales. Its financial strength lies in consistent royalty revenue and high profit margins. However, its dependence on a single partnership and vulnerability to generic competition pose risks. Strategic acquisitions are crucial for diversification, requiring careful management to ensure long-term growth. The company needs to mitigate GSK partnership risks to boost it fundamental rating.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Innoviva Inc. Investor Relations
  • SEC Filings
  • Analyst Reports
  • GSK Reports

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Market share data is approximate and may vary based on the source and definition used. Financial metrics and projections are subject to change. Please consult with a qualified financial advisor before making any investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Innoviva Inc

Exchange NASDAQ
Headquaters Burlingame, CA, United States
IPO Launch date 2004-10-05
CEO & Director Mr. Pavel Raifeld C.F.A.
Sector Healthcare
Industry Biotechnology
Full time employees 127
Full time employees 127

Innoviva, Inc. engages in the development and commercialization of pharmaceutical products in the United States and internationally. The company's products include RELVAR/BREO ELLIPTA, a once-daily combination medicine consisting of a LABA, vilanterol (VI), an inhaled corticosteroid (ICS), and fluticasone furoate; ANORO ELLIPTA, a once-daily medicine combining a long-acting muscarinic antagonist (LAMA) and umeclidinium bromide (UMEC) with a LABA, VI; GIAPREZA (angiotensin II), a vasoconstrictor to increase blood pressure in adults with septic or other distributive shock; XERAVA (eravacycline), a tetracycline class antibacterial for the treatment of complicated intra-abdominal infections in adults; XACDURO, a beta lactamase inhibitor for the treatment of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia; and ZEVTERA, a cephalosporin antibacterial for the treatment of adult patients with staphylococcus aureus bloodstream infections, adult patients with acute bacterial skin and skin structure infections, and adult and pediatric patients with community-acquired bacterial pneumonia. Its development pipeline includes Zoliflodacin, a late-stage product candidate, a potential single oral dose cure for the treatment of uncomplicated gonorrhea. Innoviva, Inc. has a strategic partnership with Sarissa Capital Management LP. It has long-acting beta2 agonist (LABA) collaboration agreement with Glaxo Group Limited to develop and commercialize once-daily products for the treatment of chronic obstructive pulmonary disease and asthma. The company was formerly known as Theravance, Inc. and changed its name to Innoviva, Inc. in January 2016. Innoviva, Inc. was incorporated in 1996 and is headquartered in Burlingame, California.