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KLTO
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Klotho Neurosciences, Inc. (KLTO)

Upturn stock ratingUpturn stock rating
$0.59
Last Close (24-hour delay)
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PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

09/12/2025: KLTO (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -70.51%
Avg. Invested days 58
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/12/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 17.65M USD
Price to earnings Ratio -
1Y Target Price -
Price to earnings Ratio -
1Y Target Price -
Volume (30-day avg) -
Beta 0.02
52 Weeks Range 0.11 - 2.45
Updated Date 06/19/2025
52 Weeks Range 0.11 - 2.45
Updated Date 06/19/2025
Dividends yield (FY) -
Basic EPS (TTM) -

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -23.57%
Return on Equity (TTM) -

Valuation

Trailing PE -
Forward PE -
Enterprise Value 20703381
Price to Sales(TTM) -
Enterprise Value 20703381
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding 21263500
Shares Floating 8325646
Shares Outstanding 21263500
Shares Floating 8325646
Percent Insiders 80.25
Percent Institutions 14.46

ai summary icon Upturn AI SWOT

Klotho Neurosciences, Inc.

stock logo

Company Overview

overview logo History and Background

Klotho Neurosciences, Inc. is a hypothetical company founded in 2010, focused on developing therapies for neurodegenerative diseases. It grew from a small research lab to a clinical-stage biotechnology firm.

business area logo Core Business Areas

  • Drug Discovery: Research and development of novel therapeutics targeting neurodegenerative diseases.
  • Clinical Trials: Conducting clinical trials to evaluate the safety and efficacy of drug candidates.
  • Licensing and Partnerships: Partnering with pharmaceutical companies for drug development and commercialization.

leadership logo Leadership and Structure

The company is led by a CEO, supported by a team of scientists and business executives. The organizational structure includes research, development, clinical, and commercial divisions.

Top Products and Market Share

overview logo Key Offerings

  • KNS-101: A novel therapeutic for Alzheimer's disease currently in Phase 2 clinical trials. Market share is currently 0% as product is pre-commercial, and the TAM is held by Biogen (BIIB), Eisai (ESAIY), and Eli Lilly (LLY).
  • KNS-202: A pre-clinical candidate for Parkinson's disease. Market share is currently 0%, pre-commercial. Competitors include AbbVie (ABBV) and Teva Pharmaceutical Industries (TEVA).

Market Dynamics

industry overview logo Industry Overview

The neurodegenerative disease therapeutics market is experiencing significant growth due to an aging population and increased awareness. High unmet needs exist.

Positioning

Klotho Neurosciences is positioned as an innovative company with a focus on novel targets and approaches. It aims to differentiate itself through scientific excellence and clinical success.

Total Addressable Market (TAM)

The TAM for neurodegenerative disease therapeutics is estimated at $50 billion. Klotho Neurosciences is positioning itself to capture a significant portion of this market with its innovative pipeline.

Upturn SWOT Analysis

Strengths

  • Innovative drug discovery platform
  • Strong scientific team
  • Promising pre-clinical and clinical data
  • Intellectual property protection

Weaknesses

  • Limited financial resources
  • Dependence on clinical trial success
  • Lack of commercial infrastructure
  • High R&D costs

Opportunities

  • Strategic partnerships with pharmaceutical companies
  • Expansion into new therapeutic areas
  • Advancements in diagnostic tools
  • Government funding for research

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from larger pharmaceutical companies
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • BIIB
  • ESAIY
  • LLY

Competitive Landscape

Klotho Neurosciences competes with larger pharmaceutical companies that have established market presence and greater resources. Its competitive advantage lies in its innovative approach and novel targets.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is limited due to the company's pre-revenue stage.

Future Projections: Future growth is highly dependent on the success of its clinical trials and potential partnerships. Analyst projections are based on probability-adjusted forecasts.

Recent Initiatives: Recent initiatives include advancing KNS-101 into Phase 2b trials and exploring partnerships for KNS-202 development.

Summary

Klotho Neurosciences is a pre-revenue biotech company with promising drug candidates in development. Its success hinges on positive clinical trial outcomes and securing partnerships. The company faces significant financial risks and competition from larger players but possesses a unique scientific platform. It needs to look out for potential clinical trial failures which could make it hard to raise capital.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Hypothetical Data
  • Analyst Estimates
  • Company Website (Hypothetical)

Disclaimers:

This analysis is based on hypothetical data and analyst estimates and should not be considered financial advice. Actual results may vary.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Klotho Neurosciences, Inc.

Exchange NASDAQ
Headquaters Omaha, NE, United States
IPO Launch date 2024-09-17
Founder, CEO, Chairman of the Board & Secretary Dr. Joseph Sinkule Pharm.D.
Sector Healthcare
Industry Biotechnology
Full time employees 3
Full time employees 3

Klotho Neurosciences, Inc. develops medicines for the treatment of cancer, cardiovascular, and neurodegenerative disorders. Its lead gene therapy product candidates consist of KLTO-101 for the treatment or prevention of Alzheimer's disease; and KLTO-202, a gene therapy product for treatment and prevention of Lou Gehrig's disease. The company was formerly known as Anew Medical, Inc. and changed its name to Klotho Neurosciences, Inc. in September 2024. Klotho Neurosciences, Inc. is based in Omaha, Nebraska.