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Lexicon Pharmaceuticals Inc (LXRX)

Upturn stock ratingUpturn stock rating
$1.1
Last Close (24-hour delay)
Profit since last BUY-9.09%
upturn advisory
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BUY since 10 days
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Upturn Advisory Summary

08/29/2025: LXRX (2-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Number of Analysts

rating

5 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $2.75

1 Year Target Price $2.75

Analysts Price Target For last 52 week
$2.75 Target price
52w Low $0.28
Current$1.1
52w High $2.17

Analysis of Past Performance

Type Stock
Historic Profit 23.76%
Avg. Invested days 31
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 3.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/29/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 417.91M USD
Price to earnings Ratio -
1Y Target Price 2.75
Price to earnings Ratio -
1Y Target Price 2.75
Volume (30-day avg) 5
Beta 1.18
52 Weeks Range 0.28 - 2.17
Updated Date 08/30/2025
52 Weeks Range 0.28 - 2.17
Updated Date 08/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.32

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Earnings Date

Report Date 2025-08-06
When -
Estimate -0.09
Actual 0.01

Profitability

Profit Margin -206.43%
Operating Margin (TTM) 12.94%

Management Effectiveness

Return on Assets (TTM) -22.14%
Return on Equity (TTM) -65.3%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 317747746
Price to Sales(TTM) 7.15
Enterprise Value 317747746
Price to Sales(TTM) 7.15
Enterprise Value to Revenue 5.44
Enterprise Value to EBITDA -2.58
Shares Outstanding 363399008
Shares Floating 183890725
Shares Outstanding 363399008
Shares Floating 183890725
Percent Insiders 1.17
Percent Institutions 72.07

ai summary icon Upturn AI SWOT

Lexicon Pharmaceuticals Inc

stock logo

Company Overview

overview logo History and Background

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company founded in 1995, focused on discovering and developing treatments for human diseases. It utilizes its gene knockout technology to identify and validate drug targets.

business area logo Core Business Areas

  • Drug Discovery and Development: Lexicon focuses on discovering and developing small molecule drugs, primarily in the areas of diabetes, oncology, and neuropathic pain. They leverage their proprietary gene knockout technology to identify novel drug targets and accelerate the drug development process.
  • Commercialization: Lexicon has a commercialized product, XERISPA (ibrexafungerp tablets), for the treatment of vulvovaginal candidiasis (VVC). They are actively involved in its marketing and sales.

leadership logo Leadership and Structure

The leadership team is comprised of experienced pharmaceutical executives and scientists. The organizational structure includes research and development, clinical operations, commercial operations, and administrative functions.

Top Products and Market Share

overview logo Key Offerings

  • XERISPA (ibrexafungerp): XERISPA is an oral antifungal medication approved for the treatment of vulvovaginal candidiasis (VVC). Launch started in June 2023. Revenue is still being generated and the market share is still low relative to other treatments. Competitors include fluconazole (Diflucan), and topical treatments.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is characterized by high R&D costs, long development timelines, and stringent regulatory requirements. The market for antifungal medications is growing, driven by increasing prevalence of fungal infections.

Positioning

Lexicon is positioned as an innovative biopharmaceutical company with a unique drug discovery platform. Its competitive advantage lies in its gene knockout technology and its ability to identify novel drug targets.

Total Addressable Market (TAM)

The TAM for antifungal therapies is estimated to be billions of dollars globally. Lexicon aims to capture a significant share of this market with XERISPA and future products.

Upturn SWOT Analysis

Strengths

  • Proprietary gene knockout technology
  • Experienced management team
  • Commercialized product (XERISPA)
  • Focus on novel drug targets

Weaknesses

  • Limited financial resources compared to larger pharmaceutical companies
  • Dependence on XERISPA for revenue
  • History of net losses
  • Susceptible to competitive responses.

Opportunities

  • Expanding XERISPA's market reach
  • Developing new products based on gene knockout technology
  • Partnering with larger pharmaceutical companies
  • Expanding into new therapeutic areas

Threats

  • Competition from established pharmaceutical companies
  • Regulatory hurdles
  • Patent expirations
  • Unsuccessful clinical trials

Competitors and Market Share

competitor logo Key Competitors

  • PFE
  • MRK
  • GILD

Competitive Landscape

Lexicon faces significant competition from larger pharmaceutical companies with greater resources. Lexicon's competitive advantage lies in their innovation and potentially superior products.

Growth Trajectory and Initiatives

Historical Growth: Please refer to Lexicon Pharmaceutical's SEC filings for historical growth data. I do not have real time access to that information.

Future Projections: Future growth projections depend on XERISPA sales and development of new products, which are subject to clinical and regulatory risk. Analyst estimates vary.

Recent Initiatives: Recent initiatives include commercializing XERISPA, advancing other pipeline products, and exploring partnerships.

Summary

Lexicon Pharmaceuticals is a developing biopharmaceutical company with a promising drug discovery platform and a recently launched product. While XERISPA presents a growth opportunity, the company's limited resources and competition pose challenges. Successful pipeline development and commercialization are crucial for long-term success. Financial performance data and continued focus on strategic partnerships is important. Overcoming regulatory and clinical trial hurdles remain high priority.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Lexicon Pharmaceuticals Investor Relations
  • SEC Filings
  • Third-party Pharmaceutical Market Reports
  • Public financial analysis websites

Disclaimers:

The information provided is for informational purposes only and should not be construed as financial advice. Investment decisions should be based on thorough research and consultation with a qualified financial advisor. Market share data is approximate and may vary.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Lexicon Pharmaceuticals Inc

Exchange NASDAQ
Headquaters The Woodlands, TX, United States
IPO Launch date 2000-04-07
CEO & Director Dr. Michael S. Exton Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 103
Full time employees 103

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company offers Sotagliflozin, an orally-delivered small molecule drug to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visits in adults with heart failure or type 2 diabetes mellitus, chronic kidney disease or CKD, and other cardiovascular risk factors. Its orally-delivered small molecule drug candidates under development include sotagliflozin for the treatment of hypertrophic cardiomyopathy or HCM and type 1 diabetes that is in Phase 3 clinical trial; LX9211, which has completed Phase II clinical trials for the treatment of neuropathic pain; and LX9851 for the treatment of obesity and associated cardiometabolic disorders, as well as for weight management. Lexicon Pharmaceuticals, Inc. has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.