Mustang Bio Inc logo

Mustang Bio Inc(MBIO)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$0.53
09/24/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for MBIO

09/24/2026: MBIO (1-star) is currently NOT-A-BUY. Pass it for now.

Mustang Bio Inc is a clinical-stage biotechnology company focused on developing CAR-T and gene therapies for cancer and genetic diseases. Its main strength lies in a specialized pipeline licensed from academic partners, though it lacks commercial products and consistent revenue. The primary growth opportunity rests on achieving positive clinical readouts that could lead to licensing deals or regulatory approvals. However, the company faces significant risks, including intense competition from larger, well-capitalized firms, and a constant need for external financing. This stock is suitable only for high-risk investors comfortable with binary outcomes, and investors should closely monitor upcoming clinical data readouts and the company's ongoing cash position.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high-risk, high-reward exposure to the biotech sector but lacks the consistent revenue growth typical of mature growth stocks.
Momentum investorWeak fitThe stock often experiences high volatility and lacks sustained, long-term upward price momentum necessary for this style.
Value investorWeak fitThe absence of earnings and positive cash flow makes standard value metrics inapplicable.
Dividend investorWeak fitMustang Bio does not pay a dividend and prioritizes capital preservation for R&D.
Low-risk investorWeak fitThe clinical-stage nature of the company involves high binary risk, making it unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical trial results can cause significant and rapid swings in the share price.
Valuation riskHighValuations are highly speculative due to the lack of commercial revenues.
Competition risk (Oncology/CAR-T)HighEstablished players possess significantly more resources to capture market share.
Business qualityMediumThe company relies on a pipeline of early-to-mid-stage assets with uncertain outcomes.
Dividend incomeLow / noneIncome generation is not part of the business model.
Execution riskHighSuccess depends entirely on the ability to conduct trials, meet regulatory standards, and secure funding.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Choppy
PRICE STABILITY

Choppy

The stock has experienced frequent reversals and pronounced short-term price swings.

Analysis of Past Performance

Type Stock
Historic Profit -18.31%
Avg. Invested days 6
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/24/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
MBIO receives a 3-star rating, supported by available scored pillars. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
MBIO has moderate overall fundamentals (3 stars), with moderate financial health, solid growth momentum, and moderate ownership. In FY2025 versus FY2024, strong earnings growth (+87.8%) is partially offset by soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%), soft profitability (net margin 0.0%).

Financial Health Rating

★★★★★
MBIO's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is MBIO's strongest growth driver at +87.8% FY2025 versus FY2024 (strong, 5 stars). By comparison, free-cash-flow growth (+53.9%, strong) is also strong, while revenue growth (+0.0%, slightly negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 9.9% and approximately 92.0% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 8.02% supports management-shareholder alignment.

Top 5 Institutional Investors

Kestra Advisory Services, LLC 2.60%
Geode Capital Management, LLC 1.22%
BlackRock Inc 1.12%
Citadel Advisors Llc 0.78%
CFO4Life Group, LLC 0.44%

Unit Economics (Per $1K Revenue)

★★★★★
MBIO generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong margins, cash conversion, and capital efficiency support the rating.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
MBIO has a liquid profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 3.88M USD
Price to earnings Ratio -
1Y Target Price 10
Price to earnings Ratio -
1Y Target Price 10
Volume (30-day avg) 23.2K shares
Beta 2.05
52 Weeks Range 0.47 - 1.85
Updated Date 09/24/2026
52 Weeks Range 0.47 - 1.85
Updated Date 09/24/2026
Dividends yield (FY) -
Basic EPS (TTM) -0.42

How Company Makes Money

Business areaWhat it includesRetail investor read
Cell and Gene Therapy R&DClinical trial development for oncology and genetic conditions.The company does not generate revenue from product sales and currently operates by burning cash to fund research.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value -13.24M
Price to Sales(TTM) 2205.73
Enterprise Value -13.24M
Price to Sales(TTM) 2205.73
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.14
Shares Outstanding 6.73M
Shares Floating 6.19M
Shares Outstanding 6.73M
Shares Floating 6.19M
Percent Insiders 8.02
Percent Institutions 9.93

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Mustang Bio Inc

Exchange NASDAQ
Headquarters Waltham, MA, United States
IPO Launch date 2017-08-22
President, CEO, Interim CFO & Director Dr. Manuel Litchman M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 4
Full time employees 4

Mustang Bio, Inc., a clinical-stage biopharmaceutical company, focuses on translating cell therapies into cures for difficult-to-treat cancers and autoimmune diseases in the United States. The company develops MB-106, a CD20-targeted chimeric antigen receptor (CAR) T cell therapy which is in Phase I clinical trail for non-hodgkin lymphoma, chronic lymphocytic leukemia, and autoimmune diseases; MB-109, a combination MB-101 and MB-108 as a potential treatment for IL13Ra2+ relapsed or refractory glioblastoma and high-grade astrocytoma; MB-101, an IL13Ra2 CAR T cell program completd Phase I for glioblastoma; and MB-108 which is in Phase I for the treatment of herpes simplex virus-1 oncolytic virus C134. It has a license agreement with city of hope national medical center and nationwide children's hospital. Mustang Bio, Inc. was incorporated in 2015 and is headquartered in Waltham, Massachusetts.