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MannKind Corp (MNKD)

Upturn stock ratingUpturn stock rating
$5.37
Last Close (24-hour delay)
Profit since last BUY18.81%
upturn advisory
Strong Buy
BUY since 14 days
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  • SELL Advisory (Loss)​
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Upturn Stock infoUpturn Stock info Stock price based on last close
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Upturn Advisory Summary

09/16/2025: MNKD (3-star) is a STRONG-BUY. BUY since 14 days. Simulated Profits (18.81%). Updated daily EoD!

Upturn Star Rating

rating

Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Number of Analysts

rating

7 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $10.57

1 Year Target Price $10.57

Analysts Price Target For last 52 week
$10.57 Target price
52w Low $3.38
Current$5.37
52w High $7.63

Analysis of Past Performance

Type Stock
Historic Profit 50.4%
Avg. Invested days 33
Today’s Advisory Strong Buy
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 5.0
Stock Returns Performance Upturn Returns Performance 3.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/16/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.71B USD
Price to earnings Ratio 48.91
1Y Target Price 10.57
Price to earnings Ratio 48.91
1Y Target Price 10.57
Volume (30-day avg) 7
Beta 1.02
52 Weeks Range 3.38 - 7.63
Updated Date 09/15/2025
52 Weeks Range 3.38 - 7.63
Updated Date 09/15/2025
Dividends yield (FY) -
Basic EPS (TTM) 0.11

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin 10.87%
Operating Margin (TTM) 13.93%

Management Effectiveness

Return on Assets (TTM) 10.63%
Return on Equity (TTM) -

Valuation

Trailing PE 48.91
Forward PE 34.84
Enterprise Value 1576870825
Price to Sales(TTM) 5.66
Enterprise Value 1576870825
Price to Sales(TTM) 5.66
Enterprise Value to Revenue 5.23
Enterprise Value to EBITDA 19.93
Shares Outstanding 306828000
Shares Floating 300980187
Shares Outstanding 306828000
Shares Floating 300980187
Percent Insiders 1.66
Percent Institutions 55.86

ai summary icon Upturn AI SWOT

MannKind Corp

stock logo

Company Overview

overview logo History and Background

MannKind Corp was founded in 1991. Its early focus was on inhaled insulin technology. A significant milestone was the FDA approval of Afrezza in 2014 (originally 2006 but later withdrawn and resubmitted). The company has evolved to focus on inhaled therapeutics.

business area logo Core Business Areas

  • Inhaled Therapeutics: MannKind focuses on developing and commercializing inhaled therapeutic products, primarily using its Technosphere platform.
  • Afrezza (Inhaled Insulin): Afrezza is MannKind's main product, an inhaled rapid-acting insulin for managing blood sugar levels in adults with diabetes mellitus.
  • Tyvaso DPI (Inhaled Treprostinil): Collaboration with United Therapeutics for Tyvaso DPI, an inhaled prostacyclin analogue for pulmonary hypertension.

leadership logo Leadership and Structure

Michael Castagna is the CEO. The company has a typical corporate structure with a board of directors and executive management team overseeing various departments like R&D, commercial operations, and finance.

Top Products and Market Share

overview logo Key Offerings

  • Afrezza: Afrezza is an inhaled rapid-acting insulin used to control high blood sugar in adults with diabetes. Market share is small relative to injected insulin. Competitors include Novo Nordisk (NovoLog, Fiasp), Eli Lilly (Humalog, Lyumjev), and Sanofi (Apidra).
  • Tyvaso DPI: Tyvaso DPI, partnered with United Therapeutics, is an inhaled prostacyclin analogue for pulmonary hypertension. Competitors include liquid Tyvaso from United Therapeutics itself and other therapies for pulmonary hypertension.

Market Dynamics

industry overview logo Industry Overview

The pharmaceutical industry is highly competitive and regulated. The diabetes and pulmonary hypertension segments are substantial markets with ongoing innovation and demand for new therapies.

Positioning

MannKind is positioned as a specialty pharmaceutical company focused on inhaled therapies. Its competitive advantage lies in its Technosphere platform, which allows for rapid absorption and precise dosing of inhaled drugs.

Total Addressable Market (TAM)

The global diabetes market is estimated at hundreds of billions of dollars. The pulmonary hypertension market is also significant, in the tens of billions. MannKind is targeting niche segments within these larger markets. The Technosphere platform could be expanded into other therapeutic areas.

Upturn SWOT Analysis

Strengths

  • Technosphere platform for rapid drug delivery
  • Afrezza's rapid-acting insulin profile
  • Partnership with United Therapeutics for Tyvaso DPI
  • Specialized focus on inhaled therapeutics

Weaknesses

  • Limited financial resources compared to larger pharmaceutical companies
  • Afrezza's slower market adoption
  • Reliance on partnerships for commercialization of some products
  • History of losses

Opportunities

  • Expansion of Technosphere platform to other therapeutic areas
  • Increased market penetration of Afrezza with improved patient education
  • Development of new inhaled therapies
  • Potential for strategic partnerships and acquisitions

Threats

  • Competition from established pharmaceutical companies
  • Regulatory challenges and clinical trial risks
  • Patent expirations
  • Economic downturns affecting healthcare spending

Competitors and Market Share

competitor logo Key Competitors

  • NVO
  • LLY
  • SNY

Competitive Landscape

MannKind faces intense competition from established diabetes and pulmonary hypertension drug manufacturers. Its competitive advantage lies in its novel inhaled drug delivery technology, but it needs to overcome challenges related to market adoption and brand awareness.

Growth Trajectory and Initiatives

Historical Growth: MannKind's growth has been uneven due to product launches, partnerships, and regulatory challenges. Revenue growth has varied, dependent on product adoption and market conditions.

Future Projections: Analyst estimates suggest continued growth driven by Afrezza and Tyvaso DPI, but these estimates are subject to change.

Recent Initiatives: Recent strategic initiatives include expanding the Afrezza sales force, partnering with United Therapeutics, and exploring new indications for the Technosphere platform.

Summary

MannKind Corp is a specialty pharmaceutical company focused on inhaled therapies, primarily Afrezza and Tyvaso DPI. The company has a novel drug delivery technology but faces significant competition. Partnerships are crucial for its success. Future growth depends on increasing market penetration and expanding its pipeline.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company Filings (SEC)
  • Analyst Reports
  • Press Releases
  • Financial News Outlets

Disclaimers:

This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be based on individual research and consultation with a qualified financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About MannKind Corp

Exchange NASDAQ
Headquaters Danbury, CT, United States
IPO Launch date 2004-07-28
CEO & Director Dr. Michael E. Castagna Pharm.D.
Sector Healthcare
Industry Biotechnology
Full time employees 403
Full time employees 403

MannKind Corporation, a biopharmaceutical company, focuses on the development and commercialization of therapeutic products and services for endocrine and orphan lung diseases in the United States. It offers Afrezza Inhalation Powder, an inhaled insulin used to improve glycemic control in adults with diabetes; the V-Go wearable insulin delivery device, which provides continuous subcutaneous infusion of insulin in adults; and Tyvaso DPI for the treatment of pulmonary arterial hypertension and pulmonary hypertension. The company's product pipeline includes MNKD-101, a nebulized formulation of clofazimine, which is in Phase 3 study, for the treatment of severe chronic and recurrent pulmonary infections, including nontuberculous mycobacterial lung disease; MNKD-201, a dry-powder formulation of nintedanib, which is in phase 1 clinical study, for the treatment of idiopathic pulmonary fibrosis (IPF); MNKD-301, which is in preclinical stage, for cystic fibrosis; and Pediatric Afrezza, which is in phase 3 clinical trial for the treatment of diabetes mellitus. It has collaboration and license agreement with United Therapeutics Corporation for development, regulatory, and commercial activities of Tyvaso DPI; and collaboration agreement with Thirona to evaluate the therapeutic for the treatment of pulmonary fibrosis. Further, the company has supply and distribution agreement with Biomm S.A. for the commercialization of Afrezza in Brazil; license and distribution agreement with Cipla Ltd. for the marketing and distribution of Afrezza in India; and co-promotion agreement with Amphastar for marketing of Baqsimi (glucagon) nasal powder. MannKind Corporation was incorporated in 1991 and is headquartered in Danbury, Connecticut.