Minerva Neurosciences Inc logo

Minerva Neurosciences Inc(NERV)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$3.4
09/25/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for NERV

09/25/2026: NERV (1-star) is currently NOT-A-BUY. Pass it for now.

Minerva Neurosciences is a clinical-stage biotechnology company focused on developing proprietary therapies for central nervous system disorders, primarily schizophrenia. The company's main strength lies in its specialized pipeline, particularly its investigative candidate Roluperidone. While the potential for a novel treatment for negative symptoms represents a significant growth opportunity, the firm faces immense execution and regulatory risks, highlighted by recent FDA setbacks. With no current commercial revenue and high development costs, the stock is a speculative, high-risk investment better suited for those comfortable with biotechnology volatility. Investors should closely monitor regulatory communications and the company's capital preservation efforts as it navigates a challenging path toward potential approval.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorWeak fitThe company lacks revenue growth, making it a speculative clinical-stage play rather than a traditional growth stock.
Momentum investorWeak fitMomentum is conditional on positive news flow and price upturns, which are currently absent.
Value investorWeak fitTraditional value metrics cannot be applied to a company without earnings or product revenue.
Dividend investorWeak fitMinerva does not pay a dividend and is unlikely to do so in the near future.
Low-risk investorWeak fitClinical-stage biotechnology carries high inherent investment risk and volatility.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighThe stock is highly sensitive to clinical trial outcomes and regulatory news.
Valuation riskHighValuation is speculative and based entirely on future development success.
Competition risk (Pharma/CNS)HighLarge incumbents with massive R&D budgets dominate the CNS market.
Business qualityLowThe company lacks a proven commercial product or stable revenue stream.
Dividend incomeLow / noneNo income potential exists for investors.
Execution riskHighSuccess depends on complex clinical and regulatory milestones.

Price Behavior

Downtrend
PRICE PATH

Downtrend

The stock has experienced a sustained decline in price over recent periods.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -11.8%
Avg. Invested days 32
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/25/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
NERV receives a 2-star rating, supported by available scored pillars. The rating is constrained by weak unit economics, and weak price momentum.

Company Fundamentals

★★★★★
NERV has moderate overall fundamentals (3 stars), with moderate financial health, soft growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-20492.7%), soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%).

Financial Health Rating

★★★★★
NERV's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
NERV's growth profile is soft, with the least-weak measure being revenue growth at +0.0% FY2025 versus FY2024. By comparison, while earnings growth (-20492.7%, negative) and free-cash-flow growth (-69007.6%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 93.3% and approximately 71.8% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 3.26% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

Federated Hermes Inc 9.78%
Vivo Capital, LLC 9.05%
HHG PLC 8.99%
Balyasny Asset Management LLC 8.92%
Logos Global Management LP 6.89%

Unit Economics (Per $1K Revenue)

★★★★★
NERV generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong margins, cash conversion, and capital efficiency support the rating.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
NERV has a liquid, relatively low-volatility profile. Weak momentum is the primary drawback.

Style Classification

Quality Focused

Value-OrientedLow VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 162.34M USD
Price to earnings Ratio -
1Y Target Price 10.33
Price to earnings Ratio -
1Y Target Price 10.33
Volume (30-day avg) 238.8K shares
Beta -0.1
52 Weeks Range 2.06 - 8.80
Updated Date 09/27/2026
52 Weeks Range 2.06 - 8.80
Updated Date 09/27/2026
Dividends yield (FY) -
Basic EPS (TTM) -36.12

How Company Makes Money

Business areaWhat it includesRetail investor read
CNS TherapeuticsClinical-stage development of drugs like Roluperidone.The company is not currently profitable and relies on research to create future products.
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Valuation

Trailing PE -
Forward PE 11.21
Enterprise Value 91.37M
Price to Sales(TTM) 1.87
Enterprise Value 91.37M
Price to Sales(TTM) 1.87
Enterprise Value to Revenue 0.03
Enterprise Value to EBITDA 0.07
Shares Outstanding 47.75M
Shares Floating 34.30M
Shares Outstanding 47.75M
Shares Floating 34.30M
Percent Insiders 3.26
Percent Institutions 93.31

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Minerva Neurosciences Inc

Exchange NASDAQ
Headquarters Burlington, MA, United States
IPO Launch date 2014-07-01
Executive Chairman, CEO & Member of Scientific Advisory Board Dr. Remy Luthringer Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 7
Full time employees 7

Minerva Neurosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of product candidates for the treatment of central nervous system diseases. Its lead product candidate is roluperidone, which is in Phase 3 confirmatory trial for the treatment of negative symptoms in patients with schizophrenia. Minerva Neurosciences, Inc. was incorporated in 2007 and is based in Burlington, Massachusetts.