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ONC
Upturn stock rating

BeiGene, Ltd. (ONC)

Upturn stock rating
$316.15
Last Close (24-hour delay)
Profit since last BUY8.89%
upturn advisory
Consider higher Upturn Star rating
BUY since 64 days
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Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

10/15/2025: ONC (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

24 Analysts rated it

Well-followed company, solid analyst reports, reliable data for confident investing.

1 Year Target Price $381.09

1 Year Target Price $381.09

Analysts Price Target For last 52 week
$381.09 Target price
52w Low $170.99
Current$316.15
52w High $355.3

Analysis of Past Performance

Type Stock
Historic Profit -25.89%
Avg. Invested days 36
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/15/2025

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 36.69B USD
Price to earnings Ratio -
1Y Target Price 381.09
Price to earnings Ratio -
1Y Target Price 381.09
Volume (30-day avg) 24
Beta 0.31
52 Weeks Range 170.99 - 355.30
Updated Date 10/17/2025
52 Weeks Range 170.99 - 355.30
Updated Date 10/17/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.69

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -3.89%
Operating Margin (TTM) 6.68%

Management Effectiveness

Return on Assets (TTM) -1.06%
Return on Equity (TTM) -4.98%

Valuation

Trailing PE -
Forward PE 47.85
Enterprise Value 38727210732
Price to Sales(TTM) 8.04
Enterprise Value 38727210732
Price to Sales(TTM) 8.04
Enterprise Value to Revenue 8.49
Enterprise Value to EBITDA 433.9
Shares Outstanding 100988458
Shares Floating 873357144
Shares Outstanding 100988458
Shares Floating 873357144
Percent Insiders 17.29
Percent Institutions 32.52

ai summary icon Upturn AI SWOT

BeiGene, Ltd.

stock logo

Company Overview

overview logo History and Background

BeiGene, Ltd. was founded in 2010 by Xiaodong Wang and Peter Fang. It is a global, science-driven biotechnology company focused on developing innovative and affordable medicines to improve treatment outcomes and access for patients worldwide. The company has evolved from a China-focused operation to a global player with operations in multiple countries.

business area logo Core Business Areas

  • Research and Development: BeiGene focuses on discovering and developing innovative oncology medicines. Their research spans early discovery through late-stage clinical development.
  • Manufacturing: BeiGene has established manufacturing capabilities, including both small molecule and biologics production.
  • Commercialization: BeiGene commercializes its own developed products and in-licensed products in various markets.

leadership logo Leadership and Structure

BeiGene is led by a team of experienced executives in the pharmaceutical industry. Key leaders include the CEO, Chief Medical Officer, and heads of various departments like R&D, manufacturing, and commercial operations. The company operates with a global structure.

Top Products and Market Share

overview logo Key Offerings

  • Brukinsa (zanubrutinib): A BTK inhibitor approved for various hematological malignancies. Brukinsa has gained market share rapidly. Competitors include Imbruvica (ibrutinib) by AbbVie and Janssen and Calquence (acalabrutinib) by AstraZeneca. Revenue contribution significant but no readily available exact market share due to multiple indications.
  • Tislelizumab: An anti-PD-1 antibody approved in several countries. It is in late stage clinical trials. Competitors are Keytruda (Merck) and Opdivo (Bristol-Myers Squibb).

Market Dynamics

industry overview logo Industry Overview

The oncology therapeutics market is large and growing, driven by an aging population, increased incidence of cancer, and advancements in treatment options like targeted therapies and immunotherapies.

Positioning

BeiGene is positioned as a global oncology company focused on innovation. Its competitive advantages include a strong R&D pipeline, global manufacturing capabilities, and a growing commercial presence. Its focus on affordability also gives it an edge in certain markets.

Total Addressable Market (TAM)

The global oncology market is estimated to be hundreds of billions of dollars. BeiGene aims to capture a significant share of this TAM through its innovative pipeline and global expansion.

Upturn SWOT Analysis

Strengths

  • Strong R&D pipeline
  • Global manufacturing capabilities
  • Innovative oncology focus
  • Experienced management team
  • Focus on Affordability

Weaknesses

  • Relatively new commercial presence compared to established players
  • Dependence on pipeline success
  • High R&D spending

Opportunities

  • Expanding into new markets
  • Developing new therapies for unmet medical needs
  • Forming strategic partnerships
  • Expanding access to innovative medicines globally

Threats

  • Competition from established pharmaceutical companies
  • Regulatory hurdles
  • Pricing pressures
  • Clinical trial failures

Competitors and Market Share

competitor logo Key Competitors

  • ABBV
  • AZN
  • MRK
  • BMY

Competitive Landscape

BeiGene faces intense competition from established pharmaceutical companies. Its advantages include innovative products and a focus on affordability. Disadvantages include a smaller commercial presence and dependence on pipeline success.

Growth Trajectory and Initiatives

Historical Growth: BeiGene has experienced rapid revenue growth in recent years, driven by product sales and market expansion.

Future Projections: Analysts project continued revenue growth for BeiGene, driven by increased adoption of Brukinsa and potential approval and launch of other pipeline products.

Recent Initiatives: Recent initiatives include expanding manufacturing capacity, advancing clinical trials, and expanding commercial operations globally.

Summary

BeiGene is a growing global oncology company with innovative products and a strong pipeline. The company faces competition from established players, and its success depends on the continued development and commercialization of its pipeline. Investment in R&D continues, but will need to manage operating costs to get to a point of breaking even. Current market share is low, but growth opportunities are there if trials continue to perform.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company filings, analyst reports, industry publications.

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. Market share data is approximate and may vary depending on the source and specific indication.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About BeiGene, Ltd.

Exchange NASDAQ
Headquaters -
IPO Launch date 2016-02-03
Co-Founder, Executive Chairman & CEO Mr. John V. Oyler
Sector Healthcare
Industry Biotechnology
Full time employees 11000
Full time employees 11000

BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company's commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton's Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; and PARTRUVIX, a selective small molecule inhibitor of PARP1 and PARP2 enzymes that is being evaluated as a monotherapy and in combinations for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK-targeting chimeric degradation activation compound active against wild-type and mutant BTK; Ociperlimab (BGB-A1217), a TIGIT inhibitor; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. The company was formerly known as BeiGene, Ltd. and changed its name to BeOne Medicines AG in May 2025. BeOne Medicines AG was founded in 2010 and is based in Basel, Switzerland.