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Oncolytics Biotech Inc (ONCY)

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Upturn Advisory Summary
10/27/2025: ONCY (2-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $4.57
1 Year Target Price $4.57
| 1 | Strong Buy |
| 4 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 45.11% | Avg. Invested days 29 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 126.47M USD | Price to earnings Ratio - | 1Y Target Price 4.57 |
Price to earnings Ratio - | 1Y Target Price 4.57 | ||
Volume (30-day avg) 6 | Beta 1.24 | 52 Weeks Range 0.33 - 1.51 | Updated Date 10/27/2025 |
52 Weeks Range 0.33 - 1.51 | Updated Date 10/27/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.26 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -74.56% | Return on Equity (TTM) -249.28% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 133915044 | Price to Sales(TTM) - |
Enterprise Value 133915044 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -1.79 | Shares Outstanding 104521702 | Shares Floating 98776415 |
Shares Outstanding 104521702 | Shares Floating 98776415 | ||
Percent Insiders - | Percent Institutions 0.27 |
Upturn AI SWOT
Oncolytics Biotech Inc

Company Overview
History and Background
Oncolytics Biotech Inc. is a Canadian biopharmaceutical company founded in 1998. It focuses on the development of oncolytic viruses for the treatment of cancer. The company's primary focus is on its lead product, pelareorep, a proprietary isolate of the reovirus.
Core Business Areas
- Research and Development: Focused on the development of pelareorep and other oncolytic viruses for cancer treatment.
- Clinical Trials: Conducting clinical trials to evaluate the safety and efficacy of pelareorep in various cancer types.
- Partnerships and Collaborations: Collaborating with other pharmaceutical companies and research institutions to advance the development and commercialization of its products.
Leadership and Structure
The company is led by a management team with expertise in oncology and virology. The organizational structure includes departments for research, clinical development, and business development.
Top Products and Market Share
Key Offerings
- Pelareorep: Pelareorep is Oncolytics Biotech's lead product, an oncolytic reovirus being developed for cancer treatment. It is currently undergoing clinical trials for multiple cancer types. Market share data is difficult to quantify at this stage, given the drug is not yet approved. Competitors include companies developing other oncolytic virus therapies, like Amgen (T-VEC/IMLYGIC) and Replimune.
Market Dynamics
Industry Overview
The oncology market is a large and rapidly growing market, driven by the increasing incidence of cancer and advancements in cancer treatment. Oncolytic virus therapies are a relatively new class of cancer treatment that are showing promise in clinical trials.
Positioning
Oncolytics Biotech is positioned as a leader in the development of oncolytic reovirus therapies. Its competitive advantage lies in its proprietary pelareorep isolate and its ongoing clinical trials.
Total Addressable Market (TAM)
The total addressable market for cancer therapies is estimated to be in the hundreds of billions of dollars. Oncolytics Biotech is positioned to capture a portion of this market with its oncolytic virus therapies, depending on clinical trial outcomes and regulatory approvals.
Upturn SWOT Analysis
Strengths
- Proprietary pelareorep isolate
- Ongoing clinical trials
- Experienced management team
- Strong intellectual property portfolio
Weaknesses
- Limited financial resources
- Reliance on clinical trial success
- Lack of approved products
- High regulatory hurdles
Opportunities
- Successful clinical trial results
- Regulatory approval of pelareorep
- Partnerships with larger pharmaceutical companies
- Expansion into new cancer types
Threats
- Clinical trial failures
- Regulatory setbacks
- Competition from other cancer therapies
- Economic downturn
Competitors and Market Share
Key Competitors
- AMGN
- REPL
- VIRI
Competitive Landscape
Oncolytics faces competition from larger pharmaceutical companies with more resources and established products. Its competitive advantage lies in its unique reovirus technology and its focus on specific cancer types.
Growth Trajectory and Initiatives
Historical Growth: Growth has been primarily driven by clinical development milestones and funding rounds.
Future Projections: Future growth is dependent on the successful completion of clinical trials and regulatory approval of pelareorep. Analyst estimates are subject to significant uncertainty.
Recent Initiatives: Recent initiatives include the initiation of new clinical trials, partnerships with research institutions, and presentations at scientific conferences.
Summary
Oncolytics Biotech is a clinical-stage biopharmaceutical company focused on developing oncolytic virus therapies. The company's success is highly dependent on the outcome of its ongoing clinical trials. While possessing a promising technology, it needs to successfully navigate regulatory hurdles and compete with larger companies. Its strong intellectual property portfolio and experienced management team are strengths, but its limited financial resources and lack of approved products are weaknesses that need to be addressed.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports
- ClinicalTrials.gov
Disclaimers:
This analysis is for informational purposes only and should not be considered financial advice. Investment decisions should be based on individual risk tolerance and thorough due diligence. Market share data and competitor analysis are estimates and may not be precise.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Oncolytics Biotech Inc
Exchange NASDAQ | Headquaters Calgary, AB, Canada | ||
IPO Launch date 1999-11-08 | CEO & Director Mr. Jared Kelly J.D., L.L.M. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 28 | Website https://oncolyticsbiotech.com |
Full time employees 28 | Website https://oncolyticsbiotech.com | ||
Oncolytics Biotech Inc., a clinical-stage biopharmaceutical company, engages in the research, development, and commercialization of oncology treatments. The company develops pelareorep, an intravenously delivered immunotherapeutic agent for the treatment of hormone receptor-positive / human epidermal growth factor 2-negative advanced and metastatic breast cancer, metastatic pancreatic ductal adenocarcinoma, and anal cancer. It has an agreement with Roche Holding AG to supply its immune checkpoint inhibitors, atezolizumab, for use in its ongoing sponsored studies. Oncolytics Biotech Inc. was incorporated in 1998 and is headquartered in Calgary, Canada.

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