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Predictive Oncology Inc (POAI)

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Upturn Advisory Summary
12/08/2025: POAI (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $3
1 Year Target Price $3
| 0 | Strong Buy |
| 0 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -3.82% | Avg. Invested days 27 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 14.46M USD | Price to earnings Ratio - | 1Y Target Price 3 |
Price to earnings Ratio - | 1Y Target Price 3 | ||
Volume (30-day avg) 1 | Beta 1.35 | 52 Weeks Range 3.88 - 33.75 | Updated Date 12/7/2025 |
52 Weeks Range 3.88 - 33.75 | Updated Date 12/7/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -141.32 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date 2025-11-14 | When - | Estimate - | Actual -107.25 |
Profitability
Profit Margin - | Operating Margin (TTM) -90654.07% |
Management Effectiveness
Return on Assets (TTM) -128.8% | Return on Equity (TTM) -746.03% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 16167330 | Price to Sales(TTM) 8.69 |
Enterprise Value 16167330 | Price to Sales(TTM) 8.69 | ||
Enterprise Value to Revenue 9.71 | Enterprise Value to EBITDA -0.51 | Shares Outstanding 3393516 | Shares Floating 1833008 |
Shares Outstanding 3393516 | Shares Floating 1833008 | ||
Percent Insiders 4.92 | Percent Institutions 0.15 |
Upturn AI SWOT
Predictive Oncology Inc

Company Overview
History and Background
Predictive Oncology Inc. (formerly Cancer Prevention Pharmaceuticals, Inc.) was founded in 2002. The company has undergone significant transformation, shifting its focus from drug development to leveraging artificial intelligence and machine learning for personalized cancer treatment. A key milestone was the rebranding to Predictive Oncology Inc., reflecting its new strategic direction. The company aims to revolutionize cancer care by providing data-driven insights to oncologists and patients.
Core Business Areas
- AI-Driven Precision Oncology Platform: The company's core offering is a proprietary AI platform designed to analyze complex genomic and clinical data from cancer patients. This platform aims to predict patient response to various therapies, identify optimal treatment pathways, and potentially uncover novel therapeutic targets. It integrates data from various sources, including genomic sequencing, imaging, and electronic health records.
- Data Analytics and Insights: Predictive Oncology provides data analytics services to healthcare providers, pharmaceutical companies, and research institutions. This includes analyzing large datasets to understand disease progression, treatment efficacy, and patient outcomes. The goal is to accelerate research and improve clinical decision-making.
Leadership and Structure
Information on the specific leadership team and detailed organizational structure is not readily available in public financial filings. Typically, companies in this sector have a CEO, a Chief Medical Officer, a Chief Technology Officer, and a CFO, along with a scientific advisory board.
Top Products and Market Share
Key Offerings
- Predictive Oncology AI Platform: A comprehensive AI-powered platform that analyzes patient data to predict treatment response and identify optimal therapies. This platform aims to guide oncologists in making personalized treatment decisions. Competitors include other AI oncology platforms and traditional genomic profiling companies. Specific market share data for this nascent area is not yet established, but the TAM is substantial. Revenue is generated through licensing and service agreements.
Market Dynamics
Industry Overview
The precision oncology market is rapidly growing, driven by advancements in genomics, AI, and a demand for personalized medicine. The industry faces challenges related to data integration, regulatory hurdles, and the need for clinical validation of AI-driven predictions. The focus is on improving patient outcomes and reducing healthcare costs.
Positioning
Predictive Oncology Inc. is positioning itself as a leader in AI-driven precision oncology. Its competitive advantage lies in its proprietary AI algorithms and its focus on integrating diverse data sources to provide actionable insights. However, as a relatively new entrant in this specific AI-focused niche, it faces established players in genomic profiling and broader AI healthcare solutions.
Total Addressable Market (TAM)
The global precision oncology market is projected to reach tens of billions of dollars in the coming years. Predictive Oncology Inc. is positioned to capture a portion of this TAM by offering its AI-driven platform to oncologists, research institutions, and pharmaceutical companies seeking to improve cancer treatment efficacy and drug discovery.
Upturn SWOT Analysis
Strengths
- Proprietary AI and machine learning algorithms for predictive analytics.
- Focus on personalized medicine and treatment optimization.
- Potential to integrate diverse patient data sources.
- Strong emphasis on scientific validation and research.
Weaknesses
- Relatively nascent company with limited commercial traction.
- Dependence on clinical validation and adoption by healthcare providers.
- Intense competition in the precision oncology and AI healthcare space.
- Potential for high research and development costs and long development cycles.
Opportunities
- Growing demand for personalized cancer treatments.
- Advancements in genomic sequencing and data analysis technologies.
- Potential partnerships with pharmaceutical companies for drug discovery and development.
- Expansion into new cancer types and therapeutic areas.
- Increasing adoption of AI in healthcare decision-making.
Threats
- Regulatory hurdles and evolving data privacy laws.
- Competition from established biotechnology and AI companies.
- Challenges in securing funding and investment.
- The complex and lengthy process of clinical trials and regulatory approval.
- Potential for misinterpretation or over-reliance on AI predictions.
Competitors and Market Share
Key Competitors
- Tempus
- Foundation Medicine (a part of Thermo Fisher Scientific)
- Guardant Health
- Caris Life Sciences
- Sophia Genetics
Competitive Landscape
Predictive Oncology Inc. faces a competitive landscape with established players offering genomic profiling and diagnostic services. Its advantage lies in its AI-centric approach to predicting treatment response, differentiating it from purely diagnostic companies. However, it needs to demonstrate superior predictive accuracy and clinical utility to gain market share.
Growth Trajectory and Initiatives
Historical Growth: Historically, the company has focused on building its technological foundation and intellectual property. Growth has been characterized by scientific advancements and strategic repositioning rather than significant revenue growth.
Future Projections: Future projections are highly dependent on successful clinical validation, market adoption of its AI platform, and securing strategic partnerships. Analyst estimates are speculative for early-stage companies, but the potential is tied to the precision oncology market growth.
Recent Initiatives: Recent initiatives likely include further development and validation of its AI platform, strategic collaborations with healthcare providers and research institutions, and efforts to secure commercial agreements.
Summary
Predictive Oncology Inc. is a development-stage company in the rapidly expanding precision oncology market, leveraging AI for personalized cancer treatment. Its strengths lie in its proprietary technology and focus on data-driven insights. However, it faces significant challenges including intense competition, the need for extensive clinical validation, and a history of financial losses. Success hinges on its ability to gain market adoption and demonstrate the efficacy of its AI platform.
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Sources and Disclaimers
Data Sources:
- Company SEC Filings (e.g., 10-K, 10-Q)
- Financial news outlets
- Industry research reports
- Company press releases
Disclaimers:
This analysis is based on publicly available information and is for informational purposes only. It does not constitute investment advice. Investors should conduct their own due diligence before making any investment decisions. Market share data and financial figures for early-stage companies can be estimates and subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Predictive Oncology Inc
Exchange NASDAQ | Headquaters Pittsburgh, PA, United States | ||
IPO Launch date 2018-01-29 | CEO & Chairman Mr. Raymond F. Vennare | ||
Sector Healthcare | Industry Health Information Services | Full time employees 23 | Website https://predictive-oncology.com |
Full time employees 23 | Website https://predictive-oncology.com | ||
Predictive Oncology Inc., a knowledge and science-driven company, applies artificial intelligence (AI) to support the discovery and development of cancer therapies. It operates through two segments, Pittsburgh and Eagan. The Pittsburgh segment provides services that include the application of AI using its proprietary biobank of 150,000+ tumor samples. This segment also creates proprietary 3D culture models used in drug development. Its Eagan segment produces the FDA-cleared STREAMWAY System and associated products for automated medical fluid waste management and patient-to-drain medical fluid disposal. Predictive Oncology Inc. has a strategic collaboration with Every Cure to identify and prioritize drugs for repurposing. The company was formerly known as Precision Therapeutics Inc. and changed its name to Predictive Oncology Inc. in June 2019. Predictive Oncology Inc. was incorporated in 2002 and is headquartered in Pittsburgh, Pennsylvania.

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