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PRLD
Upturn stock ratingUpturn stock rating

Prelude Therapeutics Inc (PRLD)

Upturn stock ratingUpturn stock rating
$0.81
Last Close (24-hour delay)
Profit since last BUY-12.22%
upturn advisory
SELL
SELL since 2 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
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Upturn Advisory Summary

06/30/2025: PRLD (1-star) is a SELL. SELL since 2 days. Profits (-12.22%). Updated daily EoD!

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

4 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $3.75

1 Year Target Price $3.75

Analysts Price Target For last 52 week
$3.75Target price
Low$0.61
Current$0.81
high$6.8

Analysis of Past Performance

Type Stock
Historic Profit -43.36%
Avg. Invested days 34
Today’s Advisory SELL
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/30/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 44.34M USD
Price to earnings Ratio -
1Y Target Price 3.75
Price to earnings Ratio -
1Y Target Price 3.75
Volume (30-day avg) 4
Beta 1.24
52 Weeks Range 0.61 - 6.80
Updated Date 06/30/2025
52 Weeks Range 0.61 - 6.80
Updated Date 06/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.68

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -1999.67%

Management Effectiveness

Return on Assets (TTM) -45.05%
Return on Equity (TTM) -81.44%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -34850760
Price to Sales(TTM) 6.33
Enterprise Value -34850760
Price to Sales(TTM) 6.33
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.54
Shares Outstanding 43610200
Shares Floating 18136236
Shares Outstanding 43610200
Shares Floating 18136236
Percent Insiders 11.37
Percent Institutions 69.69

Analyst Ratings

Rating 2
Target Price 3.75
Buy 2
Strong Buy 1
Buy 2
Strong Buy 1
Hold -
Sell 1
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Prelude Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

Prelude Therapeutics Inc. was founded in 2016. It is a clinical-stage biopharmaceutical company focused on discovering and developing small molecule therapeutics targeting critical signaling pathways implicated in cancer. The company went public in 2020.

business area logo Core Business Areas

  • Discovery and Development: Focuses on identifying and developing small molecule drugs targeting cancer-related pathways.
  • Clinical Trials: Conducts clinical trials to evaluate the safety and efficacy of its drug candidates.
  • Research and Development: Investing in R&D to develop next generation compounds.

leadership logo Leadership and Structure

Dr. Krishna Vaddi is the Chief Executive Officer. The company has a typical structure for a clinical-stage biopharmaceutical firm, with departments dedicated to research, development, clinical operations, and corporate functions.

Top Products and Market Share

overview logo Key Offerings

  • PRT2527: A CDK9 inhibitor in Phase 2 clinical development for various cancers. Market share is not yet established as the product is in clinical development. Competitors include companies developing CDK9 inhibitors such as Samus Therapeutics.
  • PRT3645: A selective SMARCA2 degrader in Phase 1 clinical development. Market share is not yet established as the product is in clinical development. No immediate competitors are listed for SMARCA2 degraders, but other oncology companies targeting similar pathways exist.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is highly competitive and research-intensive. It faces challenges from regulatory hurdles, clinical trial risks, and pricing pressures.

Positioning

Prelude Therapeutics is positioned as an innovative company focused on novel cancer therapies. Its competitive advantage lies in its specific target pathways and potential first-in-class or best-in-class drugs.

Total Addressable Market (TAM)

The total addressable market for cancer therapies is estimated to be billions of dollars annually. Prelude Therapeutics aims to capture a significant portion of this market with its targeted therapies. Specific TAM estimates for each drug candidate would depend on the cancer type and line of therapy.

Upturn SWOT Analysis

Strengths

  • Innovative drug development pipeline
  • Strong focus on specific cancer targets
  • Experienced leadership team

Weaknesses

  • Early-stage clinical development risks
  • Limited financial resources compared to larger pharmaceutical companies
  • Dependence on successful clinical trial outcomes

Opportunities

  • Potential for breakthrough therapies in unmet medical needs
  • Partnerships with larger pharmaceutical companies
  • Expansion of pipeline through acquisitions or collaborations

Threats

  • Clinical trial failures
  • Regulatory setbacks
  • Competition from other pharmaceutical companies

Competitors and Market Share

competitor logo Key Competitors

  • GILD
  • MRK
  • BMY

Competitive Landscape

Prelude Therapeutics faces competition from larger pharmaceutical companies with established oncology portfolios. Its success depends on demonstrating superior efficacy and safety with its novel drug candidates.

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been characterized by pipeline development, clinical trial initiation, and funding activities.

Future Projections: Future growth is dependent on the success of clinical trials and the potential for commercialization of its drug candidates. Analyst estimates should be consulted for specific revenue projections.

Recent Initiatives: Recent initiatives include progressing lead drug candidates through clinical trials and exploring potential partnerships.

Summary

Prelude Therapeutics is a clinical-stage biopharmaceutical firm with a promising pipeline of novel cancer therapies targeting specific signaling pathways. Its strength lies in its innovative approach and experienced team, but its success depends on overcoming clinical trial risks. Financial stability and potential partnerships will be crucial for long-term growth, but is currently in a competitive landscape with other established pharmaceutical companies.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company filings, analyst reports, press releases, and reputable financial news sources.

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. Investment decisions should be based on individual research and consultation with a qualified financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Prelude Therapeutics Inc

Exchange NASDAQ
Headquaters Wilmington, DE, United States
IPO Launch date 2020-09-25
Founder, CEO & Director Dr. Krishna Vaddi D.V.M., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 131
Full time employees 131

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT3789, a selective degrader of SMARCA2 protein for the treatment of advanced or metastatic solid tumors with loss of SMARCA4 due to truncating mutation and/or deletion; PRT7732, a selective and orally bioavailable SMARCA2 degraders to treat advanced or metastatic solid tumors; and PRT2527, a cyclin-dependent kinase 9 inhibitor for the treatment of advanced solid tumors. The company's CDK9 program is a regulator of cancer-promoting transcriptional programs, including MCL1, MYC, and MYB. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware.