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QNCX
Upturn stock ratingUpturn stock rating

Quince Therapeutics, Inc. (QNCX)

Upturn stock ratingUpturn stock rating
$1.68
Last Close (24-hour delay)
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PASS
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  • SELL Advisory (Loss)​
  • Profit
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Upturn Advisory Summary

08/14/2025: QNCX (3-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Number of Analysts

rating

4 Analysts rated it

Very few follow this stock; limited insights, higher-risk early investing.

1 Year Target Price $7.5

1 Year Target Price $7.5

Analysts Price Target For last 52 week
$7.5 Target price
52w Low $0.54
Current$1.68
52w High $2.45

Analysis of Past Performance

Type Stock
Historic Profit 80.38%
Avg. Invested days 40
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 4.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/14/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 90.24M USD
Price to earnings Ratio -
1Y Target Price 7.5
Price to earnings Ratio -
1Y Target Price 7.5
Volume (30-day avg) 4
Beta 1.02
52 Weeks Range 0.54 - 2.45
Updated Date 08/15/2025
52 Weeks Range 0.54 - 2.45
Updated Date 08/15/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.1

Earnings Date

Report Date 2025-08-12
When -
Estimate -0.26
Actual -0.3251

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -19.33%
Return on Equity (TTM) -167.04%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 73019180
Price to Sales(TTM) -
Enterprise Value 73019180
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA 1.44
Shares Outstanding 53713800
Shares Floating 44768839
Shares Outstanding 53713800
Shares Floating 44768839
Percent Insiders 11.12
Percent Institutions 19.26

ai summary icon Upturn AI SWOT

Quince Therapeutics, Inc.

stock logo

Company Overview

overview logo History and Background

Quince Therapeutics, Inc. (formerly Cortexyme, Inc.) is a biopharmaceutical company focused on acquiring, developing, and commercializing innovative therapeutics to treat debilitating diseases. Founded to treat Alzheimer's disease, the company has shifted its focus towards rare diseases. Its current name change reflects the shift in corporate strategy and focus.

business area logo Core Business Areas

  • Rare Disease Therapeutics Development: Quince's primary focus is developing therapies for rare diseases. This includes clinical trials, regulatory submissions, and potential commercialization of these products.
  • Biopharmaceutical Research: Quince invests in research activities aimed at identifying and developing novel therapeutic candidates.
  • Acquisition and Licensing: Quince actively seeks to acquire or license promising drug candidates to expand its pipeline.

leadership logo Leadership and Structure

Quince Therapeutics is led by a management team with experience in biopharmaceutical development and commercialization. The organizational structure consists of various departments including research and development, clinical operations, regulatory affairs, and business development.

Top Products and Market Share

overview logo Key Offerings

  • Beryvamate: Beryvamate is a lead product candidate being developed for Niemann-Pick disease type C (NPC), a rare and progressive genetic disorder. Phase 2 study results are awaited for efficacy. Competitors are limited due to the rare nature of the condition. Zavesca (miglustat) is an approved drug, but not optimal, and is offered by Actelion Pharmaceuticals (owned by Johnson & Johnson (JNJ)).
  • Other Preclinical Programs: Quince has preclinical programs targeting other rare diseases. Details on market share are not applicable at this stage.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is characterized by high research and development costs, long development timelines, and strict regulatory oversight. Rare disease drug development offers potential for orphan drug designation, market exclusivity, and premium pricing.

Positioning

Quince Therapeutics is positioned as a rare disease focused biopharmaceutical company, differentiating itself through its focus on acquiring and developing therapies for underserved patient populations. Their advantage lies in potential orphan drug designation benefits.

Total Addressable Market (TAM)

The total addressable market (TAM) for rare disease therapeutics is substantial and growing. While the individual markets for each rare disease are small, collectively they represent a significant opportunity. Quince's positioning focuses on capturing a portion of this expanding market, aiming for therapies with high unmet needs.

Upturn SWOT Analysis

Strengths

  • Focus on rare diseases with high unmet needs
  • Experienced management team
  • Potential for orphan drug designation and market exclusivity
  • Pipeline of therapeutic candidates

Weaknesses

  • Dependence on successful clinical trial outcomes
  • High research and development costs
  • Limited revenue generation
  • Relatively small market capitalization

Opportunities

  • Acquisition or licensing of promising drug candidates
  • Advancement of pipeline programs through clinical development
  • Potential for partnerships or collaborations
  • Expansion into new therapeutic areas

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from larger pharmaceutical companies
  • Changes in reimbursement policies

Competitors and Market Share

competitor logo Key Competitors

  • JNJ
  • VRTX
  • AMGN

Competitive Landscape

Quince faces competition from larger, more established pharmaceutical companies with greater financial resources and more advanced product pipelines. Quince must differentiate itself through innovation and focus on underserved patient populations.

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been characterized by investment in research and development, rather than revenue generation.

Future Projections: Future growth is dependent on successful clinical trial outcomes and potential regulatory approvals. Analyst estimates vary widely, depending on the perceived probability of success for the company's pipeline programs.

Recent Initiatives: Recent initiatives include advancing Beryvamate through clinical trials, exploring potential acquisitions or licensing opportunities, and focusing on expanding the pipeline.

Summary

Quince Therapeutics is a development-stage biopharmaceutical company focused on rare diseases. Its potential rests on clinical trial successes and strategic acquisitions. The company's financial performance depends heavily on securing financing and achieving regulatory approvals. Investors should closely monitor clinical trial data and regulatory developments.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • SEC Filings (10-K, 10-Q), Company Website, Press Releases, Analyst Reports, Market Research Reports

Disclaimers:

This analysis is for informational purposes only and should not be considered financial advice. The information provided is based on publicly available data and may not be completely accurate or up-to-date. Investment decisions should be based on thorough research and consultation with a qualified financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Quince Therapeutics, Inc.

Exchange NASDAQ
Headquaters South San Francisco, CA, United States
IPO Launch date 2019-05-09
CEO, Chief Medical Officer & Director Dr. Dirk Thye M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 36
Full time employees 36

Quince Therapeutics, Inc., a biopharmaceutical company, focuses on acquiring, developing, and commercializing therapeutics for patients with debilitating and rare diseases. The company's lead asset candidature comprises EryDex for the treatment of rare pediatric neurodegenerative disease, including A-T, an inherited autosomal recessive neurodegenerative and immunodeficiency disorder caused by mutations in ATM gene. Its AIDE technology platform, a drug/device combination platform that uses an automated process to encapsulate a drug into a patient's own red blood cells, as well as consists of an automated equipment the RCL, a sterile single-use consumable treatment kit comprising kit medical devices, syringe kit, and process solutions. The company was formerly known as Cortexyme, Inc. and changed its name to Quince Therapeutics, Inc. in August 2022. The company was incorporated in 2012 and is headquartered in South San Francisco, California.