- Chart
- Upturn Summary
- Highlights
- Revenue
- Valuation
- About
QuantumSi Inc (QSI)

- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- Pass (Skip investing)
Stock price based on last close (see disclosures)
- ALL
- 1Y
- 1M
- 1W
Upturn Advisory Summary
12/05/2025: QSI (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $2.85
1 Year Target Price $2.85
| 1 | Strong Buy |
| 1 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -66.79% | Avg. Invested days 24 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 310.31M USD | Price to earnings Ratio - | 1Y Target Price 2.85 |
Price to earnings Ratio - | 1Y Target Price 2.85 | ||
Volume (30-day avg) 3 | Beta 2.99 | 52 Weeks Range 0.95 - 5.77 | Updated Date 12/7/2025 |
52 Weeks Range 0.95 - 5.77 | Updated Date 12/7/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.67 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -4419.57% |
Management Effectiveness
Return on Assets (TTM) -26.84% | Return on Equity (TTM) -52.44% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 89071117 | Price to Sales(TTM) 97.67 |
Enterprise Value 89071117 | Price to Sales(TTM) 97.67 | ||
Enterprise Value to Revenue 28.04 | Enterprise Value to EBITDA 0.63 | Shares Outstanding 195552165 | Shares Floating 177964295 |
Shares Outstanding 195552165 | Shares Floating 177964295 | ||
Percent Insiders 11.62 | Percent Institutions 30.85 |
Upturn AI SWOT
QuantumSi Inc

Company Overview
History and Background
QuantumSi Inc. was founded in 2017 by researchers from the University of Florida, aiming to revolutionize protein analysis. The company's core innovation is its 'LiquidArray' platform, a single-molecule, highly sensitive protein detection system. Significant milestones include the development of its first assay, the securing of venture capital funding, and its subsequent public offering (IPO) via a SPAC merger in February 2022 under the ticker symbol QSI. The company has evolved from a research-focused entity to a commercializing enterprise focused on various life science applications.
Core Business Areas
- Protein Analysis Platform Development: QuantumSi is developing and commercializing its proprietary LiquidArray platform, a technology designed for ultra-sensitive, single-molecule detection and quantification of proteins. This platform aims to enable new levels of discovery and diagnostic capabilities in various life science applications.
- Assay Development and Applications: The company is focused on developing specific assays for various applications, including drug discovery, precision medicine, and diagnostics. These assays leverage the sensitivity of the LiquidArray platform to detect and quantify target proteins with high accuracy.
Leadership and Structure
QuantumSi Inc. is led by a management team with experience in biotechnology and commercialization. Key leadership roles typically include a CEO, CTO, and heads of R&D, sales, and operations. The company operates on a functional organizational structure, with departments dedicated to research, development, manufacturing, sales, and marketing.
Top Products and Market Share
Key Offerings
- Competitors: Thermo Fisher Scientific, Bio-Rad Laboratories, Agilent Technologies, Roche Diagnostics, and various specialized proteomics companies.
- Description: The core technological platform that enables single-molecule protein detection. It utilizes a microfluidic chip and advanced optical detection to identify and quantify proteins at extremely low concentrations. Competitors in the broader protein analysis market include companies offering ELISA, mass spectrometry, and other immunoassay platforms.
- Market Share Data: Not publicly disclosed for this specific platform in its nascent commercial stage.
- Product Name 1: LiquidArray Platform
- Competitors: Depends on the specific assay target; broad competitors include companies developing ELISA kits, Western blot reagents, and other protein detection tools.
- Description: Specific assay kits and protocols designed for particular applications, such as identifying biomarkers for drug discovery or monitoring therapeutic response. The market share for these specific early-stage assays is not yet established as the platform is in its early commercialization phase. Competitors are diverse, depending on the specific biological target.
- Market Share Data: Not publicly disclosed.
- Product Name 2: Early Stage Assays (e.g., for Drug Discovery)
Market Dynamics
Industry Overview
The life sciences and biotechnology industry, particularly in protein analysis and diagnostics, is characterized by rapid innovation, increasing demand for sensitive and accurate detection methods, and significant investment in research and development. The precision medicine and personalized healthcare trends are driving the need for advanced tools to understand biological pathways and disease mechanisms at a molecular level.
Positioning
QuantumSi is positioning itself as a disruptor in the protein analysis market with its unique single-molecule detection technology. Its competitive advantage lies in its potential for unprecedented sensitivity and quantification capabilities, which could enable novel applications and insights not achievable with existing technologies. However, as a relatively new entrant with a novel technology, it faces the challenge of market adoption and proving its performance and cost-effectiveness compared to established methods.
Total Addressable Market (TAM)
The TAM for protein analysis tools and related services is substantial, encompassing research, diagnostics, and drug discovery markets. Estimates vary widely, but the global protein analysis market is projected to grow significantly, potentially reaching tens of billions of dollars in the coming years. QuantumSi is positioned to capture a segment of this market by offering a superior detection technology for specific applications where extreme sensitivity is paramount.
Upturn SWOT Analysis
Strengths
- Proprietary single-molecule detection technology (LiquidArray platform)
- Potential for unprecedented sensitivity and quantification
- Experienced scientific and management team
- Focus on high-growth areas like precision medicine and drug discovery
Weaknesses
- Early stage of commercialization with limited revenue history
- Need for extensive validation and adoption by the scientific community
- High cost of technology development and manufacturing
- Reliance on external funding to support R&D and commercialization
Opportunities
- Growing demand for advanced protein analysis in research and diagnostics
- Partnerships with pharmaceutical companies and research institutions
- Expansion into new application areas (e.g., infectious disease diagnostics)
- Leveraging AI and machine learning for data analysis from the platform
Threats
- Competition from established protein analysis technologies
- Challenges in achieving widespread market adoption and reimbursement
- Regulatory hurdles for diagnostic applications
- Technological obsolescence if new innovations emerge
Competitors and Market Share
Key Competitors
- Thermo Fisher Scientific (TMO)
- Bio-Rad Laboratories (BIO)
- Agilent Technologies (A)
- Roche Holding AG (RHHBY)
Competitive Landscape
QuantumSi Inc. faces a competitive landscape dominated by large, established players with a wide range of existing protein analysis tools and a strong customer base. Its advantage lies in its novel technology, aiming to offer a step-change in sensitivity and quantification. Disadvantages include its lack of established market presence, brand recognition, and the need to overcome the inertia of adoption for a new technology. The company's success will depend on demonstrating clear advantages in specific applications and building trust within the scientific and clinical communities.
Growth Trajectory and Initiatives
Historical Growth: Historically, QuantumSi has experienced growth in its technological development and team expansion, transitioning from a research concept to a pre-commercialization entity. Financial growth in terms of revenue is yet to be established.
Future Projections: Future projections are based on the company's ability to successfully commercialize its LiquidArray platform and achieve widespread adoption. Analyst estimates, if available, would focus on revenue ramp-up and market penetration assumptions. These projections are inherently speculative for early-stage companies.
Recent Initiatives: Recent initiatives likely focus on scaling up manufacturing capabilities, building out its commercial and sales teams, securing strategic partnerships, and conducting clinical validations or real-world application studies to demonstrate the platform's value.
Summary
QuantumSi Inc. is an early-stage biotechnology company with a novel single-molecule protein detection platform (LiquidArray). Its strengths lie in its innovative technology and potential for high sensitivity, targeting growing markets in precision medicine and drug discovery. However, it faces significant challenges in market adoption, competition from established players, and the need for substantial funding to achieve commercial success. The company must effectively demonstrate its technology's superiority and build a strong commercial presence to overcome these hurdles and realize its growth potential.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company investor relations websites
- SEC filings (10-K, 10-Q)
- Financial news and analysis platforms
- Market research reports (general industry data)
Disclaimers:
This analysis is based on publicly available information and general market understanding. It is not intended as financial advice. Investors should conduct their own due diligence before making any investment decisions. Market share data and financial projections are estimates and subject to change. Company-specific financial data requires consulting the latest official filings.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About QuantumSi Inc
Exchange NASDAQ | Headquaters Branford, CT, United States | ||
IPO Launch date 2021-06-10 | President, CEO & Director Mr. Jeffrey Alan Hawkins | ||
Sector Healthcare | Industry Medical Devices | Full time employees 149 | Website https://www.quantum-si.com |
Full time employees 149 | Website https://www.quantum-si.com | ||
Quantum-Si incorporated, a life sciences company, engages in the development of single-molecule detection platform to enable Next Generation Protein Sequencing (NGPS). The company offers Platinum NGPS instrument that provides single molecule amino acid level resolution with a streamlined workflow, including automated data analysis that accessible to researchers in all laboratory types; Platinum Pro NGPS instrument, a single molecule amino acid resolution, which provides an enhanced user interface, cloud or on instrument data analysis and an available pro mode; Library preparation kits to prepare protein sample for sequencing; Barcoding Kits to optimize the workflow and performance of technology; and Sequencing Kits contains the reagents and consumables used to perform NGPS on the Platinum or Platinum Pro instrument. It also provides Platinum Analysis Software, a cloud-based solution that automates data analysis workflows and provides a user-friendly interface and visualization of the sequencing results. Its products are used in antibody characterization, biomarker identification, protein identification, protein variants, protein barcoding, and post translational modification analysis applications. Quantum-Si incorporated was founded in 2013 is headquartered in Branford, Connecticut.

Note: This website is maintained by Upturn Corporation, which is an investment adviser registered with the U.S. Securities and Exchange Commission. Such registration does not imply a certain level of skill or training. Investing in securities has risks. Past performance is no guarantee of future returns. No assurance is provided as to any particular investment return, and you may lose money using our services. You are strongly advised to consult appropriate counsel before making any investments in companies you learn about through our services. You should obtain appropriate legal, tax, investment, accounting, and other advice that takes into account your investment portfolio and overall financial situation. You are solely responsible for conducting due diligence on a potential investment. We do not affect trades for you. You will select your own broker through which to transact. Investments are not FDIC insured, they are not guaranteed, and they may lose value. Please see the Privacy Policy, Terms of Use, and Disclosure for more information.
Home 

