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QuantumSi Inc (QSI)

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Upturn Advisory Summary
01/07/2026: QSI (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $2.68
1 Year Target Price $2.68
| 1 | Strong Buy |
| 1 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -66.79% | Avg. Invested days 24 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 275.83M USD | Price to earnings Ratio - | 1Y Target Price 2.68 |
Price to earnings Ratio - | 1Y Target Price 2.68 | ||
Volume (30-day avg) 3 | Beta 3.03 | 52 Weeks Range 0.95 - 3.10 | Updated Date 01/7/2026 |
52 Weeks Range 0.95 - 3.10 | Updated Date 01/7/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.67 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -4419.57% |
Management Effectiveness
Return on Assets (TTM) -26.84% | Return on Equity (TTM) -52.44% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 53515322 | Price to Sales(TTM) 86.82 |
Enterprise Value 53515322 | Price to Sales(TTM) 86.82 | ||
Enterprise Value to Revenue 16.84 | Enterprise Value to EBITDA 0.63 | Shares Outstanding 195552165 | Shares Floating 177852240 |
Shares Outstanding 195552165 | Shares Floating 177852240 | ||
Percent Insiders 11.62 | Percent Institutions 30.86 |
Upturn AI SWOT
QuantumSi Inc

Company Overview
History and Background
QuantumSi Inc. was founded in 2014 by David Fan. The company is focused on developing a next-generation, high-throughput, single-molecule sequencing platform for the life sciences industry. A significant milestone was its public debut via a SPAC merger in February 2022, becoming a publicly traded entity under the ticker symbol QSI. The company has been dedicated to advancing its technology for widespread adoption in research and clinical applications.
Core Business Areas
- Sequencing Technology Development: QuantumSi is primarily engaged in the research, development, and commercialization of its proprietary single-molecule sequencing technology, designed to offer high accuracy and throughput at a lower cost compared to existing methods.
- Instrument and Reagent Sales: The company aims to generate revenue from the sale of its sequencing instruments and associated reagents, consumables, and software.
Leadership and Structure
QuantumSi Inc. is led by a management team with expertise in life sciences, engineering, and business. Key figures include David Fan (Founder and CEO) and others in scientific and operational roles. The company is structured to support its R&D efforts, manufacturing, and go-to-market strategies.
Top Products and Market Share
Key Offerings
- TalentSeq Platform: QuantumSi's flagship offering is the TalentSeq platform, a novel single-molecule sequencing system. It is designed to provide high accuracy, long reads, and cost-effectiveness. The market for sequencing technologies is highly competitive, with major players like Illumina (ILMN) and Thermo Fisher Scientific (TMO). QuantumSi aims to capture market share by offering a differentiated technological approach. Specific market share data for the TalentSeq platform is not yet widely established due to its nascent stage.
Market Dynamics
Industry Overview
The DNA sequencing market is a rapidly growing segment within the biotechnology and life sciences industries. Driven by advancements in genomics, personalized medicine, and diagnostics, the demand for faster, more accurate, and cost-effective sequencing solutions is increasing. Key trends include the expansion of next-generation sequencing (NGS) applications in research, clinical diagnostics, and drug discovery.
Positioning
QuantumSi is positioning itself as an innovator in the sequencing space with its unique single-molecule approach, aiming to disrupt the market by offering a potentially superior combination of accuracy, throughput, and cost. Its competitive advantage lies in its proprietary technology designed for high performance.
Total Addressable Market (TAM)
The global DNA sequencing market is substantial and projected to continue growing significantly. Estimates for the TAM vary, but are in the tens of billions of dollars, encompassing research, clinical diagnostics, and pharmaceutical applications. QuantumSi is targeting a significant portion of this market, particularly where its technology offers distinct benefits.
Upturn SWOT Analysis
Strengths
- Proprietary single-molecule sequencing technology with potential for high accuracy and throughput.
- Experienced leadership team with expertise in the life sciences and biotechnology sectors.
- Novel approach to sequencing that could offer a competitive edge.
- Focus on a high-growth market (genomics and sequencing).
Weaknesses
- Relatively new to the market, with limited commercialization history and established customer base.
- Dependence on continued technological innovation and successful product adoption.
- Significant capital requirements for R&D, manufacturing, and market penetration.
- Unproven long-term reliability and scalability in diverse real-world applications.
Opportunities
- Growing demand for advanced genomic sequencing in personalized medicine and diagnostics.
- Potential for partnerships and collaborations with research institutions and pharmaceutical companies.
- Expansion into new application areas such as infectious disease surveillance and agricultural genomics.
- Technological advancements could lead to cost reductions and increased accessibility.
Threats
- Intense competition from established players with significant market share and resources.
- Rapid pace of technological change in the sequencing industry, requiring continuous innovation.
- Regulatory hurdles and the need for validation for clinical applications.
- Potential for alternative sequencing technologies to emerge and displace current methods.
- Economic downturns or funding challenges impacting R&D and commercialization.
Competitors and Market Share
Key Competitors
- Illumina Inc. (ILMN)
- Thermo Fisher Scientific Inc. (TMO)
- Pacific Biosciences of California Inc. (PACB)
- Oxford Nanopore Technologies plc (ONT)
Competitive Landscape
QuantumSi faces formidable competition from established giants like Illumina, which dominates the NGS market with its established technology and extensive customer base. Thermo Fisher Scientific is also a major player with a broad portfolio. QuantumSi's advantage lies in its novel single-molecule approach, which aims to offer superior performance characteristics and potentially lower costs, but it must overcome the incumbents' market penetration and brand recognition.
Growth Trajectory and Initiatives
Historical Growth: Historically, QuantumSi's growth has been characterized by intensive R&D investment and technological development, rather than significant revenue or profit growth. The period following its SPAC merger marks its transition into a publicly traded entity with a focus on commercialization.
Future Projections: Future projections are contingent on the successful launch and market adoption of its TalentSeq platform. Analyst estimates, if available, would typically focus on projected revenue growth as the company scales its operations and sales. Key indicators will be the rate of instrument placements and reagent consumption.
Recent Initiatives: Recent initiatives likely involve scaling up manufacturing capabilities, building out its sales and marketing teams, and engaging with early adopters and potential customers to validate its technology and market fit. Strategic partnerships and ongoing product development are also key.
Summary
QuantumSi Inc. is an innovative early-stage company in the high-growth genomics sequencing market. Its proprietary single-molecule technology offers potential advantages in accuracy and cost. However, it faces intense competition from established players and requires substantial capital for R&D and commercialization. Key to its success will be market adoption of its TalentSeq platform and effective management of its cash burn while navigating a rapidly evolving technological landscape.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company official filings (e.g., SEC filings)
- Financial news and analysis websites
- Industry reports on the genomics and sequencing market
Disclaimers:
This analysis is based on publicly available information and is for informational purposes only. It does not constitute financial advice. Investors should conduct their own due diligence before making any investment decisions. Market share data is estimated and subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About QuantumSi Inc
Exchange NASDAQ | Headquaters Branford, CT, United States | ||
IPO Launch date 2021-06-10 | President, CEO & Director Mr. Jeffrey Alan Hawkins | ||
Sector Healthcare | Industry Medical Devices | Full time employees 149 | Website https://www.quantum-si.com |
Full time employees 149 | Website https://www.quantum-si.com | ||
Quantum-Si incorporated, a life sciences company, engages in the development of single-molecule detection platform to enable Next Generation Protein Sequencing (NGPS). The company offers Platinum NGPS instrument that provides single molecule amino acid level resolution with a streamlined workflow, including automated data analysis that accessible to researchers in all laboratory types; Platinum Pro NGPS instrument, a single molecule amino acid resolution, which provides an enhanced user interface, cloud or on instrument data analysis and an available pro mode; Library preparation kits to prepare protein sample for sequencing; Barcoding Kits to optimize the workflow and performance of technology; and Sequencing Kits contains the reagents and consumables used to perform NGPS on the Platinum or Platinum Pro instrument. It also provides Platinum Analysis Software, a cloud-based solution that automates data analysis workflows and provides a user-friendly interface and visualization of the sequencing results. Its products are used in antibody characterization, biomarker identification, protein identification, protein variants, protein barcoding, and post translational modification analysis applications. Quantum-Si incorporated was founded in 2013 is headquartered in Branford, Connecticut.

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